Low Cost Eye Tracking: The Current Panorama.

Despite the availability of accurate, commercial gaze tracker devices working with infrared (IR) technology, visible light gaze tracking constitutes an interesting alternative by allowing scalability and removing hardware requirements. Over the last years, this field has seen examples of research showing performance comparable to the IR alternatives. In this work, we survey the previous work on remote, visible light gaze trackers and analyze the explored techniques from various perspectives such as calibration strategies, head pose invariance, and gaze estimation techniques. We also provide information on related aspects of research such as public datasets to test against, open source projects to build upon, and gaze tracking services to directly use in applications. With all this information, we aim to provide the contemporary and future researchers with a map detailing previously explored ideas and the required tools.

WM-DOVA maps for accurate polyp highlighting in colonoscopy: Validation vs. saliency maps from physicians.

We introduce in this paper a novel polyp localization method for colonoscopy videos. Our method is based on a model of appearance for polyps which defines polyp boundaries in terms of valley information. We propose the integration of valley information in a robust way fostering complete, concave and continuous boundaries typically associated to polyps. This integration is done by using a window of radial sectors which accumulate valley information to create WM-DOVA (Window Median Depth of Valleys Accumulation) energy maps related with the likelihood of polyp presence. We perform a double validation of our maps, which include the introduction of two new databases, including the first, up to our knowledge, fully annotated database with clinical metadata associated. First we assess that the highest value corresponds with the location of the polyp in the image. Second, we show that WM-DOVA energy maps can be comparable with saliency maps obtained from physicians' fixations obtained via an eye-tracker. Finally, we prove that our method outperforms state-of-the-art computational saliency results. Our method shows good performance, particularly for small polyps which are reported to be the main sources of polyp miss-rate, which indicates the potential applicability of our method in clinical practice.

Impact of image preprocessing methods on polyp localization in colonoscopy frames.

In this paper we present our image preprocessing methods as a key part of our automatic polyp localization scheme. These methods are used to assess the impact of different endoluminal scene elements when characterizing polyps. More precisely we tackle the influence of specular highlights, blood vessels and black mask surrounding the scene. Experimental results prove that the appropriate handling of these elements leads to a great improvement in polyp localization results.

Categorization and segmentation of intestinal content frames for wireless capsule endoscopy.

Wireless capsule endoscopy (WCE) is a device that allows the direct visualization of gastrointestinal tract with minimal discomfort for the patient, but at the price of a large amount of time for screening. In order to reduce this time, several works have proposed to automatically remove all the frames showing intestinal content. These methods label frames as {intestinal content- clear} without discriminating between types of content (with different physiological meaning) or the portion of image covered. In addition, since the presence of intestinal content has been identified as an indicator of intestinal motility, its accurate quantification can show a potential clinical relevance. In this paper, we present a method for the robust detection and segmentation of intestinal content in WCE images, together with its further discrimination between turbid liquid and bubbles. Our proposal is based on a twofold system. First, frames presenting intestinal content are detected by a support vector machine classifier using color and textural information. Second, intestinal content frames are segmented into {turbid, bubbles, and clear} regions. We show a detailed validation using a large dataset. Our system outperforms previous methods and, for the first time, discriminates between turbid from bubbles media.

Intestinal motility assessment with video capsule endoscopy: automatic annotation of phasic intestinal contractions.

Intestinal motility assessment with video capsule endoscopy arises as a novel and challenging clinical fieldwork. This technique is based on the analysis of the patterns of intestinal contractions shown in a video provided by an ingestible capsule with a wireless micro-camera. The manual labeling of all the motility events requires large amount of time for offline screening in search of findings with low prevalence, which turns this procedure currently unpractical. In this paper, we propose a machine learning system to automatically detect the phasic intestinal contractions in video capsule endoscopy, driving a useful but not feasible clinical routine into a feasible clinical procedure. Our proposal is based on a sequential design which involves the analysis of textural, color, and blob features together with SVM classifiers. Our approach tackles the reduction of the imbalance rate of data and allows the inclusion of domain knowledge as new stages in the cascade. We present a detailed analysis, both in a quantitative and a qualitative way, by providing several measures of performance and the assessment study of interobserver variability. Our system performs at 70% of sensitivity for individual detection, whilst obtaining equivalent patterns to those of the experts for density of contractions.

Anisotropic feature extraction from endoluminal images for detection of intestinal contractions.

Wireless endoscopy is a very recent and at the same time unique technique allowing to visualize and study the occurrence of contractions and to analyze the intestine motility. Feature extraction is essential for getting efficient patterns to detect contractions in wireless video endoscopy of small intestine. We propose a novel method based on anisotropic image filtering and efficient statistical classification of contraction features. In particular, we apply the image gradient tensor for mining informative skeletons from the original image and a sequence of descriptors for capturing the characteristic pattern of contractions. Features extracted from the endoluminal images were evaluated in terms of their discriminatory ability in correct classifying images as either belonging to contractions or not. Classification was performed by means of a support vector machine classifier with a radial basis function kernel. Our classification rates gave sensitivity of the order of 90.84% and specificity of the order of 94.43% respectively. These preliminary results highlight the high efficiency of the selected descriptors and support the feasibility of the proposed method in assisting the automatic detection and analysis of contractions.

Predictive (un)distortion model and 3-D reconstruction by biplane snakes.

This paper is concerned with the three-dimensional (3-D) reconstruction of coronary vessel centerlines and with how distortion of X-ray angiographic images affects it. Angiographies suffer from pincushion and other geometrical distortions, caused by the peripheral concavity of the image intensifier (II) and the nonlinearity of electronic acquisition devices. In routine clinical practice, where a field-of-view (FOV) of 17-23 cm is commonly used for the acquisition of coronary vessels, this distortion introduces a positional error of up to 7 pixels for an image matrix size of 512 x 512 and an FOV of 17 cm. This error increases with the size of the FOV. Geometrical distortions have a significant effect on the validity of the 3-D reconstruction of vessels from these images. We show how this effect can be reduced by integrating a predictive model of (un)distortion into the biplane snakes formulation for 3-D reconstruction. First, we prove that the distortion can be accurately modeled using a polynomial for each view. Also, we show that the estimated polynomial is independent of focal length, but not of changes in anatomical angles, as the II is influenced by the earth's magnetic field. Thus, we decompose the polynomial into two components: the steady and the orientation-dependent component. We determine the optimal polynomial degree for each component, which is empirically determined to be five for the steady component and three for the orientation-dependent component. This fact simplifies the prediction of the orientation-dependent polynomial, since the number of polynomial coefficients to be predicted is lower. The integration of this model into the biplane snakes formulation enables us to avoid image unwarping, which deteriorates image quality and therefore complicates vessel centerline feature extraction. Moreover, we improve the biplane snake behavior when dealing with wavy vessels, by means of using generalized gradient vector flow. Our experiments show that the proposed methods in this paper decrease up to 88% the reconstruction error obtained when geometrical distortion effects are ignored. Tests on imaged phantoms and real cardiac images are presented as well.