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3.
An Pediatr (Barc) ; 73(6): 357-60, 2010 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-20833119

RESUMO

UNLABELLED: Multifocal epithelial hyperplasia (MEH), or Heck disease, is a disease of the oral mucosa rarely seen in Spain. It is caused by the human papillomavirus (HPV), and is mainly associated with types 13 and 32. It appears in childhood (3-18 years) and a higher prevalence is reported in women and certain ethnic groups (American Indians and Eskimos). It consists of a benign, asymptomatic epithelial proliferation in the form of multiple papules of 3-10mm with a normal oral mucosa colour. The case involves an Ecuadorian male of 14 years, with papulous lesions in the oral mucosa with onset at 4 years of age. His 32 year-old mother had identical lesions. CONCLUSION: We present two members of an ecuadorian family with MEH. Although it is a rare disease in Spain, we must take this disease into account, given the increase in the immigrant population in Spain.


Assuntos
Hiperplasia Epitelial Focal/patologia , Adolescente , Adulto , Saúde da Família , Feminino , Humanos , Masculino
4.
Allergol. immunopatol ; 34(6): 280-281, nov. 2006.
Artigo em En | IBECS | ID: ibc-051681

RESUMO

Fixed drug eruptions due to ibuprofen have rarely been described. Two days after treatment with ibuprofen, a 61-year-old woman developed erythema and pain affecting the tongue and oral mucosa. Two months later, the patient started ibuprofen and erythromycin for a catarrhal episode with reappearance of the same lesions in the oral mucosa 24 hours later. Furthermore, two new erythematosus-violaceous maculae developed. Topical challenge through an occluded patch test with ibuprofen 5 % on the residual cutaneous lesion was positive. We present an unusual case of fixed drug eruption due to ibuprofen


Rara vez se ha descrito algún caso de erupción fija medicamentosa debida al ibuprofeno. Una paciente de 61 años de edad, presentó eritema y dolor que afectaban a la lengua y la mucosa oral, dos días después de haber tomado ibuprofeno. Dos meses después, por un episodio catarral, volvió a tomar ibuprofeno además de eritromicina. Veinticuatro horas después reaparecieron las lesiones de la mucosa oral y además dos maculas eritemato-vesiculosas. La provocación tópica con prueba del parche con ibuprofeno al 5% sobre la lesión cutánea residual, resultó positiva, confirmando la causalidad de ese medicamento en la reacción atópica


Assuntos
Feminino , Pessoa de Meia-Idade , Humanos , Ibuprofeno/efeitos adversos , Ibuprofeno/uso terapêutico , Hipersensibilidade/complicações , Hipersensibilidade/diagnóstico , Mucosa Bucal/patologia , Língua/patologia , Hipersensibilidade a Drogas/complicações , Hipersensibilidade a Drogas/diagnóstico , Testes do Emplastro/métodos , Eritromicina/uso terapêutico , Dor/diagnóstico , Dor/etiologia , Dor/terapia , Hipersensibilidade a Drogas/terapia , Testes do Emplastro/tendências , Testes do Emplastro
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