[Key mechanisms of damage and adaptation in the body under the multi-factoral effect of ecotoxicants]. / Kliuchevye mekhanizmy povrezhdeniia i adaptatsii v organizme pri mnogofaktorom vliianii ékotoksikantov.

Toxicants, that are present in chemical productions, influence functioning of protective mechanisms of the workers. The examined people have an increased content of the average molecular mass oligopeptides, changed ionic molecular composition of blood. Antioxidant protection with catalase participation is high. The accelerated replacement of membrane components displays an adaptation of organism to the chemical stress conditions.

Influence of Ukrain on patients with surgically treated breast cancer. Part IV. Electromicroscopic and cytochemical evaluation.

The present studies were undertaken to evaluate by light and by electron microscopy the influence of Ukrain on the morphology of breast cancer. The studies were carried out on material obtained from ten patients with breast cancer, treated preoperatively with Ukrain. Control material for the studies was obtained from patients of similar age and advancement of the disease, who did not receive Ukrain. The data obtained in the present studies indicate that Ukrain is responsible for severe changes in morphology of tumour cells. Histological examination by both light and electron microscopy revealed cells characteristic of those undergoing apoptosis. The stromal changes of the tumour were characterized by intensive proliferation of the connective tissue accompanied by an immune reaction expressed by mononuclear infiltrates.