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Carbohydr Polym ; 94(1): 199-208, 2013 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-23544529

RESUMO

This work aimed to develop nanocomposite films of methyl cellulose (MC) incorporated with pediocin and zinc oxide nanoparticles (nanoZnO) using the central composite design and response surface methodology. This study evaluated film physical-mechanical properties, including crystallography by X-ray diffraction, mechanical resistance, swelling and color properties, microscopy characterization, thermal stability, as well as antimicrobial activity against Staphylococcus aureus and Listeria monocytogenes. NanoZnO and pediocin affected the crystallinity of MC. Load at break and tensile strength at break did not differ among films. NanoZnO and pediocin significantly affected the elongation at break. Pediocin produced yellowish films, but nano ZnO balanced this effect, resulting in a whitish coloration. Nano ZnO exhibited good intercalation in MC and the addition of pediocin in high concentrations resulted crater-like pits in the film surfaces. Swelling of films diminished significantly compared to control. Higher concentrations of Nano ZnO resulted in enhanced thermal stability. Nanocomposite films presented antimicrobial activity against tested microorganisms.


Assuntos
Antibacterianos/química , Bacteriocinas/química , Nanocompostos/química , Nanopartículas/química , Óxido de Zinco/química , Algoritmos , Antibacterianos/farmacologia , Bacteriocinas/farmacologia , Testes de Sensibilidade a Antimicrobianos por Disco-Difusão , Embalagem de Alimentos , Modelos Lineares , Listeria monocytogenes/efeitos dos fármacos , Metilcelulose/química , Tamanho da Partícula , Staphylococcus aureus/efeitos dos fármacos , Propriedades de Superfície , Resistência à Tração , Termogravimetria , Difração de Raios X , Óxido de Zinco/farmacologia
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