RESUMO
Cryptophthalmos is a rare ocular cup malformation, which is classified among autosomal dominant inherited diseases, but often it occurs sporadically. The pathology is characterized by the absence of eyelids or palpebral fissure or their hypoplasia, as well as by abnormal development of the eye, especially of its anterior segment. The article describes a case of total cryptophthalmos without any associated malformations, with macrophthalmos on the right eye and abortive cryptophthalmos on the left in a one-year old girl. A pathomorphological investigation of the enucleated right eyeball was carried out.
Assuntos
Microftalmia , Pálpebras , Feminino , Humanos , Lactente , ÓrbitaRESUMO
The ultrastructure of macrophages detected in rats after subcutaneous implantation of the dispersed allogenic Alloplant biomaterial was studied. It was found that with the Alloplant biomaterial implantation the conditions were created promoting the concentration and complete maturation of different macrophage subpopulations. Their functional activity and interaction with other cellular populations result in complete regeneration of the connective tissue. The data obtained confirm the concept of main regulatory role of macrophages in the intercellular interactions during tissue repair and support the hypothesis of bicomponent mechanism of collagen fiber formation in the place of the Alloplant biomaterial implantation.