Effects of maternal left lateral position and rest on amniotic fluid index: a prospective clinical study.

OBJECTIVE: To compare the effect of both maternal rest and activity on the amniotic fluid index (AFI). STUDY DESIGN: Power analysis indicated that in order to achieve 20 mm of increase in AFI with 90% of power at one side alpha of 0.01, we needed at least 51 women in each group. The study group was comprised of pregnant women (n = 152) with a normal AFI and a singleton pregnancy at 26-40 weeks' gestation. Their AFI was determined by averaging the 2 repetitive measurements of the 4 amniotic fluid quadrants. The "rest" group (n = 77) was instructed to lie and rest in the left lateral position, and the "mild activity" group (n = 75) was instructed to sit and walk. RESULTS: AFI increased significantly, from 151.25 +/- 37.40 mm to 173.79 +/- 39.76 mm, in the "rest" group (p = 0.00). However, the change from 153.69 +/- 37.94 to 152.34 +/- 36.62 mm was not significant in the "mild activity" group (p = 0.167). CONCLUSION: Maternal rest in the left lateral position increases the AFI.

The first case of Horn Kolb Syndrome in Turkey, diagnosed prenatally at the 23(rd) week of a pregnancy: A very rare and unusual case far from the original geography.

BACKGROUND: The aim of this report was to evaluate and announce the first documented appearance of Horn Kolb syndrome in Turkey. CASE REPORT: Acheiropodia (Horn Kolb Syndrome) is the bilateral congenital amputation of the distal parts of the 4 extremities. It is an autosomal recessive developmental disorder. The characteristic features are amputation of the upper and lower extremities with aplasia of the hands and feet. The disorder affects only the extremities without other systemic manifestations. In this report, we present the first known case of Horn Kolb syndrome in Turkey, along with the diagnostic features. CONCLUSIONS: Severe dysmorphic skeletal anomalies should be excluded as soon as the earlier gestational weeks in every pregnancy by visualizing all 4 limbs of the fetus in routine prenatal ultrasound screening.