[The study of the frequency of AB0 blood groups in blood component donors and cancer inpatients].

The frequency of AB0 blood groups was analyzed in donors and cancer patients. Blood group A(II) was found to be more common in patients with cancers at various sites. Blood groups 0(I) (35.9%) and A(II) (35.6%) were most common in donors. This seems to be linked with that the subjects with blood group 0(I) are actively involved in donation. The study allow conclusion that it is expedient to incorporate blood samples from cancer inpatients into an immunohematological assay for antigen A variants.

[The transfusion aspects of allogeneic bone marrow transplantation]. / Transfuziologicheskie aspekty allogennoi transplantatsii kostnogo mozga.

AIM: Analysis of transplantations of allogenic bone marrow (BM) for determination of transfusiological problems arising in various types of donor's and recipient's blood ABO incompatibility. MATERIALS AND METHODS: 46 allogenic BM transplantations from relative donors are analysed. The following types of ABO incompatibility were identified: significant (12 donor-recipient pairs), insignificant (10 pairs), combined (2 pairs). RESULTS: The proposed methods of BM fractionation provided the yield of nucleated cells in minimal admixture of red cells. This allowed to minimize loss of stem cells at fractionation and to prevent acute hemolysis at infusion of BM suspension in cases of ABO group-different BM allotransplantations. CONCLUSION: The proposed modification of the "shelf" method enabled effective fractionation of small BM volumes obtained from children-BM donors with high yield of nucleated cells and small admixture of incompatible red cells. Reinfusion of erythrocytic mass obtained at fractionation of donor BM fractionation used as replacement therapy makes allogenic blood transfusion unnecessary in 66% of BM donors.