[A new sorbent for the treatment of intestinal infections]. / Novyi sorbent dlia likuvannia kyshkovykh infektsii.

A new inorganic sorbent is proposed endowed with high adsorption-chemical activity towards microorganisms. Animal studies showed that the preparation "Evirhip" is superior to coal-based sorbents (KAY and CKN) and polymethilsiloxan (PMS) towards pathogenic microorganisms, PMS having relatively higher adhesive activity towards Salmonellas than coal-based sorbents.

[The sodium form of sudamate--a new low-toxicity antimicrobial preparation]. / Natriieva forma sudamata--novyi nyz'kotoksychnyi antymikrobnvi preparat.

A new low-toxic antimicrobial preparation is proposed to impregnate woven materials used in treatment of pyo-inflammatory wounds contaminated with Gram-positive and Gram-negative bacteria as well as with pathogenic fungi as a result of an artificial infection. Sodic form of sudamate is less toxic, its bactericidal effect being 3-5 times more effective than that of hexachlorophene.

[The inorganic sorbent Evirkhip for water decontamination]. / Neorhanichnyi sorbent "Evirkhip" dlia znezarazhuvannia vody.

Inorganic synthetic sorbent "Evirhip" is recommended for eliminating of contaminants from water with varying degree of pollution. Comparative evaluation was carried out of the activities of the synthetic sorbent, natural dispersive minerals and activated charcoals with their surfaces being variously modified, using a model of typical representatives of intestinal microorganisms (Shigella sonnei, poliomyelitis type II, Sabin strain, viruses). Under stationary conditions of interaction of 1% sorbent "Evirhip" with Shigella sonnei sterilizing effect begins to reveal itself within 60 minutes. Decrease in infectivity of poliovirus occurs by one logarithm of the original level during 30 minutes contact. The paper discusses changes of cationic composition of water as a result of treating it by the sorbent, and feasibility of practical application of the sorbent in processes removing etiological agents of the intestinal infections from drinking, natural and waste water.

[A new sorbent used for preparing the intestines for a surgical intervention]. / Novyi sorbent, zastosovannyi dlia pidhotovky kyshechnyka do operatyvnoho vtruchannia.

A new sorbent with a high sorptive capacity and antimicrobial properties against different species of microorganisms (aerobic and anaerobic) is suggested. Its effectiveness has been proved both in vitro and in vivo. The authors consider that the sorbent can be recommended for clinical trials with the aim of its use in preparation of the intestine for the operation.

[An agent imparting antimicrobial properties to woven materials]. / Ahent dlia nadannia antymikrobnykh vlastyvostei tkanym materialam.

The proposed agent for the woven materials impregnation gives them antibacterial properties concerning gram-negative and gram-positive microflora, and have also the fungicidal activity. It high effectiveness testifies the vast resources of an agent in the treatment and prophylaxis of surgical pyo-inflammatory infection.

[The determination of the antiviral activity of the sorbent Evirkhip (in vitro studies)]. / Vyznachennia protyvirusnoï aktyvnosti sorbenta "Evirkhip" (doslidy in vitro).

It was found that "Evirkhip" possesses a marked antiviral activity confirmed on a model of enteroviruses (coxsackie). The authors also studied the resistance to the drug in the chain: eukaryotic cell-viral particle-prokaryotic cell. The resistance decreased with the shift to right.

[The possibility of the germination of spores of pathogenic clostridia and bacilli in soil]. / Vozmozhnost' prorastaniia spor patogennykh klostridii i batsill v pochve.

A possibility of germination of clostridia (Cl. tetani and Cl. perfringens) and bacilli (Bac. anthracis, STI vaccine strain) has been studied in model experiments with native soil. Mature spores did not germinate upon contact with native soil of deferent agrochemical types. Addition of meat-pepton medium and other protein, amino acid, and sugar-containing media led only to "swelling" of spores. The data obtained support the conclusions drawn by many researches that pathogenic clostridia and bacilli do not germinate in soil.

[Morphology of erythroblastic bone marrow islands in hematologic patients]. / Morfologiia éritroblasticheskikh ostrovkov kostnogo mozga gematologicheskikh bol'nykh.

Erythroblastic islands (EI) available for light-microscopic study were obtained from 25 patients with a haemopoiesis pathology from the ileum bone using the method suggested by the authors. Erythropoiesis activation in the osteomyelofibrosis in the erythremic stage, erythremia and haemolytic anemia was followed by the appearance in the "crown" of the central macrophage from 34 to 37 nucleated erythroid cells, enhanced phagocytosis of the normoblast nuclei and the presence of 2-4 nucleoli in the macrophage and proerythroblast nuclei.

The effect of carbohydrates on the sporogenesis of Clostridium perfringens and Bacillus anthracis.

The authors studied the effect of a number of carbohydrates on the sporogenesis of Clostridium perfringens and Bacillus anthracis (vaccine strain STI) as probable soil factors capable of influencing the duration of survival of these causative agents in the external environment. Differences in the effect of the same sugars on the formation of spores by these microorganisms and clearly expressed sporogenesis-inhibiting effect of glucose (and also of lactose in clostridia) have been demonstrated. The analysis of the peculiarities of sporogenesis under unadjusted and stabilized pH values provides a basis for regarding the "glucose effect" as repression of sporogenesis in the given causative agent, but not as inhibition resulting from considerable acidification of the culture medium. This is essential for the soil conditions characterized by high buffer capacity. The ecological value of substances of carbohydrate nature consists in their important role in the energetics and trophicity of microbial coenoses of the soil which cannot fail reflecting on the fate of pathogenic microorganisms in the soil.