[Preparation of human albumin preparations]. / Pripremanje humanih albuminskih preparata.

Structure, physical and biochemical characteristics of albumin have already been investigated and described in full detail. Preparation of albumin solution preparations of various concentrations for human application started more than 40 years ago. Person deserving most credit for it is E. Cohn, who first used ethyl alcohol on low temperatures for the separation of certain fractions among which albumin took the largest part. Many modifications of Cohn's method are used today, though the most frequently used one is modification by Kistler and Nitschman. Some new methods appeared recently, ensuring higher degree of economy and efficacy, better yield of albumin and higher purity of final preparations. One of those methods--chromatography method--is recommended by Swedish authors (J. Curling et al.). Thanks to its multiple physiological functions and stability, albumin takes very important place in therapy of many diseases, both in peace and in states of emergency.

Human red cell glutamic-pyruvic transaminase polymorphism in Serbia, Yugoslavia.

The polymorphism of red cell glutamic-pyruvic transaminase (GPT) was studied in 277 unrelated voluntary blood donors from the population of Serbia (Yugoslavia). The following phenotype frequencies were observed: GPT 1 0.309, GPT 2-1 0.454 and GPT 2 0.206, while gene frequencies were: GPT1 0.556 and GPT2 0.454.