[Chromatography of thrombin and antithrombin III on biospecific silochromes]. / Khromatohrafiia trombinu ta antytrombinu III na biospetsyfichnykh sylokhromakh.

It was shown that the seaweed sulfopolysaccharides Furcellaria and Phyllophora--furcellaran and phyllophoran--are the competitive inhibitors of thrombin-induced fibrinogen clotting. Biospecific adsorbents for thrombin and antithrombin III (AT III) isolation were synthesized with heparin, phyllophoran and furcellaran as ligands on aminopropylsilochrome and this proteins sorption characteristics on this sorbents in comparisons with heparin-cellulose and heparin-sepharose were investigated. Possible application of the synthesized adsorbents both for thrombin, AT III purification from blood products and for alpha-thrombin, beta and gamma-thrombin separation are discussed.

[Experimental data on the hygienic regulation of dimethyl phosphite in the air of a work area]. / Eksperimental'nye dannye k gigienicheskoi reglamentatsii dimetilfosfita v vozdukhe rabochei zony.

Dimethylphosphite, being a semiproduct of chlorophosphonium synthesis, is a moderately toxic substance according to the criterion of acute toxicity. It is characterized by marked cumulative properties, absorption from skin and local irritative action. Acute and chronic poisoning induces disorders of the nervous system. MAC in the air is 0.5 mg/m3 as established by Ministry of Health.