RESUMO
Endoprosthetic replacement of large joints is frequently followed by great blood loss and evolving postoperative anemia. Three hundred and thirty-seven cases of endoprosthetic hip joint replacement were retrospectively analyzed. The total frequency of allogenic hemotransfusion was 16.9%. The data of the analysis made and the review of literature support that preoperative anemia and revising intervention are the leading risk factors of allogenic hemotransfusion. Allogenic packed red blood cell transfusion is associated with the higher frequency of postoperative complications and longer hospitalization. The routine use of intraoperative autohemotransfusion has shown its low efficiency while drainage blood reinfusion can reduce the need for donor blood preparations. At present there is a great variety of effective agents whose introduction into clinical practice makes it possible to considerably reduce the need for allogenic hemotransfusion during endoprosthetic replacement of large joints and to improve the results of treatment.
Assuntos
Anemia/prevenção & controle , Artroplastia de Quadril/efeitos adversos , Perda Sanguínea Cirúrgica , Transfusão de Sangue , Anemia/sangue , Anemia/etiologia , Anemia/terapia , Doadores de Sangue , Transfusão de Sangue Autóloga , Feminino , Hemoglobinas/análise , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do TratamentoRESUMO
In a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.
