1.
2.
J Org Chem
; 75(22): 7962-5, 2010 Nov 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21033724
RESUMO
The development of a modular synthesis of 3-substituted-2-pyrones is described. The attainment of this strategy hinges on a new electrophilic pyrone derivative which can be readily prepared on a multigram scale and which performs very competently in metal-catalyzed cross-coupling reactions with a variety of nucleophiles.