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1.
Med Phys ; 48(12): 8062-8074, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34725831

RESUMO

PURPOSE: We have experimentally and computationally characterized the PTW microSilicon 60023-type diode's performance in 6 and 15 MV photon fields ≥5 × 5 mm2 projected to isocenter. We tested the detector on- and off-axis at 5 and 15 cm depths in water, and investigated whether its response could be improved by including within it a thin airgap. METHODS: Experimentally, detector readings were taken in fields generated by a Varian TrueBeam linac and compared with doses-to-water measured using Gafchromic film and ionization chambers. An unmodified 60023-type diode was tested along with detectors modified to include 0.6, 0.8, and 1.0 mm thick airgaps. Computationally, doses absorbed by water and detectors' sensitive volumes were calculated using the EGSnrc/BEAMnrc Monte Carlo radiation transport code. Detector response was characterized using k Q c l i n , 4 cm f c l i n , 4 cm , a factor that corrects for differences in the ratio of dose-to-water to detector reading between small fields and the reference condition, in this study 5 cm deep on-axis in a 4 × 4 cm2 field. RESULTS: The greatest errors in measurements of small field doses made using uncorrected readings from the unmodified 60023-type detector were over-responses of 2.6% ± 0.5% and 5.3% ± 2.0% determined computationally and experimentally, relative to the reading-per-dose in the reference field. Corresponding largest errors for the earlier 60017-type detector were 11.9% ± 0.6% and 11.7% ± 1.4% over-responses. Adding even the thinnest, 0.6 mm, airgap to the 60023-type detector over-corrected it, leading to under-responses of up to 4.8% ± 0.6% and 5.0% ± 1.8% determined computationally and experimentally. Further, Monte Carlo calculations indicate that a detector with a 0.3 mm airgap would read correctly to within 1.3% on-axis. The ratio of doses at 15 and 5 cm depths in water in a 6 MV 4 × 4 cm2 field was measured more accurately using the unmodified 60023-type detector than using the 60017-type detector, and was within 0.3% of the ratio measured using an ion chamber. The 60023-type diode's sensitivity also varied negligibly as dose-rate was reduced from 13 to 4 Gy min-1 by decreasing the linac pulse repetition frequency, whereas the sensitivity of the 60017-type detector fell by 1.5%. CONCLUSIONS: The 60023-type detector performed well in small fields across a wide range of beam energies, field sizes, depths, and off-axis positions. Its response can potentially be further improved by adding a thin, 0.3 mm, airgap.


Assuntos
Fótons , Radiometria , Método de Monte Carlo , Aceleradores de Partículas , Água
2.
Phys Med Biol ; 65(15): 155011, 2020 08 10.
Artigo em Inglês | MEDLINE | ID: mdl-32392539

RESUMO

PURPOSE: In small megavoltage photon fields, the accuracies of an unmodified PTW 60017-type diode dosimeter and six diodes modified by adding airgaps of thickness 0.6-1.6 mm and diameter 3.6 mm have been comprehensively characterized experimentally and computationally. The optimally thick airgap for density compensation was determined, and detectors were micro-CT imaged to investigate differences between experimentally measured radiation responses and those predicted computationally. METHODS: Detectors were tested on- and off-axis, at 5 and 15 cm depths in 6 and 15 MV fields ≥ 0.5 × 0.5 cm2. Computational studies were carried out using the EGSnrc/BEAMnrc Monte Carlo radiation transport code. Experimentally, radiation was delivered using a Varian TrueBeam linac and doses absorbed by water were measured using Gafchromic EBT3 film and ionization chambers, and compared with diode readings. Detector response was characterized via the [Formula: see text] formalism, choosing a 4 × 4 cm2 reference field. RESULTS: For the unmodified 60017 diode, the maximum error in small field doses obtained from diode readings uncorrected by [Formula: see text] factors was determined as 11.9% computationally at +0.25 mm off-axis and 5 cm depth in a 15 MV 0.5 × 0.5 cm2 field, and 11.7% experimentally at -0.30 mm off-axis and 5 cm depth in the same field. A detector modified to include a 1.6 mm thick airgap performed best, with maximum computationally and experimentally determined errors of 2.2% and 4.1%. The 1.6 mm airgap deepened the modified dosimeter's effective point of measurement by 0.5 mm. For some detectors significant differences existed between responses in small fields determined computationally and experimentally, micro-CT imaging indicating that these differences were due to within-tolerance variations in the thickness of an epoxy resin layer. CONCLUSIONS: The dosimetric performance of a 60017 diode detector was comprehensively improved throughout 6 and 15 MV small photon fields via density compensation. For this approach to work well with good detector-to-detector reproducibility, tolerances on dense component dimensions should be reduced to limit associated variations of response in small fields, or these components should be modified to have more water-like densities.


Assuntos
Radiometria/instrumentação , Desenho de Equipamento , Método de Monte Carlo , Aceleradores de Partículas , Fótons , Doses de Radiação , Reprodutibilidade dos Testes , Água , Microtomografia por Raio-X
3.
Z Med Phys ; 30(1): 24-39, 2020 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-31585786

RESUMO

For any detector to be used for the determination of absorbed dose at the point of measurement in water a basic equation is required to convert the reading of the detector into absorbed dose in water. The German DIN 6800 part 1 provides a general formalism for that. A further differentiated formalism applicable to photon dosimetry is suggested in this work. This modified formalism presents the two following still general and at the same time fundamental properties of any dosimetry detector: a) a clear distinction of correction factors with respect to the physical processes involved during the measurement, and b) the fact that the process of energy absorption in the detector is determined by the spectral distribution of the fluence of the secondary charged particles. It is concluded that based on the modified formalism and knowing this spectral distribution within the detector a general method is available with benefits for ionization chambers as well as for any other dosimetry detector and which is applicable at reference as well as non-reference conditions without any preconditions.


Assuntos
Doses de Radiação , Água/química , Humanos , Íons/química , Fenômenos Físicos
4.
Med Phys ; 46(6): 2752-2759, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30972756

RESUMO

PURPOSE: Discrepancy between experimental and Monte Carlo simulated dose-response of the microDiamond (mD) detector (type 60019, PTW Freiburg, Germany) at small field sizes has been reported. In this work, the radiation-induced charge imbalance in the structural components of the detector has been investigated as the possible cause of this discrepancy. MATERIALS AND METHODS: Output ratio (OR) measurements have been performed using standard and modified versions of the mD detector at nominal field sizes from 6 mm × 6 mm to 40 mm × 40 mm. In the first modified mD detector (mD_reversed), the type of charge carriers collected is reversed by connecting the opposite contact to the electrometer. In the second modified mD detector (mD_shortened), the detector's contacts have been shortened. The third modified mD detector (mD_noChip) is the same as the standard version but the diamond chip with the sensitive volume has been removed. Output correction factors were calculated from the measured OR and simulated using the EGSnrc package. An adapted Monte Carlo user-code has been used to study the underlying mechanisms of the field size-dependent charge imbalance and to identify the detector's structural components contributing to this effect. RESULTS: At the smallest field size investigated, the OR measured using the standard mD detector is >3% higher than the OR obtained using the modified mD detector with reversed contact (mD_reversed). Combining the results obtained with the different versions of the detector, the OR have been corrected for the effect of radiation imbalance. The OR obtained using the modified mD detector with shortened contacts (mD_shortened) agree with the corrected OR, all showing an over-response of less than 2% at the field sizes investigated. The discrepancy between the experimental and simulated output correction factors has been eliminated after accounting for the effect of charge imbalance. DISCUSSIONS AND CONCLUSIONS: The role of radiation-induced charge imbalance on the dose-response of mD detector in small field dosimetry has been studied and quantified. It has been demonstrated that the effect is significant at small field sizes. Multiple methods were used to quantify the effect of charge imbalance with good agreement between Monte Carlo simulations and experimental results obtained with modified detectors. When this correction is applied to the Monte Carlo data, the discrepancy from experimental data is eliminated. Based on the detailed component analysis using an adapted Monte Carlo user-code, it has been demonstrated that the effect of charge imbalance can be minimized by modifying the design of the detector's contacts.


Assuntos
Diamante , Radiometria/instrumentação , Método de Monte Carlo
5.
Z Med Phys ; 29(3): 272-281, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30340801

RESUMO

The purpose of this study was to investigate the suitability of the microDiamond detector (mDD) type 60019 (PTW-Freiburg, Germany) for radial dose function measurements with High Dose Rate (HDR) 192Ir brachytherapy sources. An HDR 192Ir source model mHDR v2r (Nucletron BV, an Elekta company, The Netherlands) was placed at the centre of a MP3 water phantom (PTW-Freiburg, Germany) within a 4F needle. Three mDDs were employed to measure the radial dose function of the source by acquiring profiles along the source transverse axis. Meanwhile, the experimental setup was simulated using the Monte Carlo (MC) code MCNP6.1™ (Los Alamos National Laboratory, USA) to calculate phantom-size, absorbed-dose energy dependence and volume averaging correction factors. After applying the correction factors, the radial dose function gL(r) for the line source approximation was calculated as defined in the TG-43 formalism at radial distances from 0.5cm to 10cm and compared to the consensus gL(r) (ESTRO and AAPM). The percentage differences to the consensus gL(r) for all the three mDDs were from -2.3% to +1.4% for distances r≤5cm and -6.2% to +2.6% for larger distances. These results indicate the suitability of the mDD for HDR brachytherapy measurements when all required corrections are applied.


Assuntos
Braquiterapia , Diamante , Radioisótopos de Irídio/uso terapêutico , Microtecnologia/instrumentação , Método de Monte Carlo , Radiometria/instrumentação , Irídio , Isótopos , Imagens de Fantasmas , Dosagem Radioterapêutica , Incerteza
6.
Z Med Phys ; 26(1): 88-94, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26323984

RESUMO

In this work, the performance of a microDiamond detector in a scanned proton beam is studied and its potential role in the dosimetric characterization of proton pencil beams is assessed. The linearity of the detector response with the absorbed dose and the dependence on the dose-rate were tested. The depth-dose curve and the lateral dose profiles of a proton pencil beam were measured and compared to reference data. The feasibility of calibrating the beam monitor chamber with a microDiamond detector was also studied. It was found the detector reading is linear with the absorbed dose to water (down to few cGy) and the detector response is independent of both the dose-rate (up to few Gy/s) and the proton beam energy (within the whole clinically-relevant energy range). The detector showed a good performance in depth-dose curve and lateral dose profile measurements; and it might even be used to calibrate the beam monitor chambers-provided it is cross-calibrated against a reference ionization chamber. In conclusion, the microDiamond detector was proved capable of performing an accurate dosimetric characterization of proton pencil beams.


Assuntos
Diamante/efeitos da radiação , Terapia com Prótons/métodos , Radiometria/instrumentação , Relação Dose-Resposta à Radiação , Desenho de Equipamento , Análise de Falha de Equipamento , Dosagem Radioterapêutica , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
7.
J Radiat Res ; 56(6): 912-8, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26268483

RESUMO

A synthetic single crystal diamond detector (SCDD) is commercially available and is characterized for radiation dosimetry in various radiation beams in this study. The characteristics of the commercial SCDD model 60019 (PTW) with 6- and 15-MV photon beams, and 208-MeV proton beams, were investigated and compared with the pre-characterized detectors: Semiflex (model 31010) and PinPoint (model 31006) ionization chambers (PTW), the EDGE diode detector (Sun Nuclear Corp) and the SFD Stereotactic Dosimetry Diode Detector (IBA). To evaluate the effects of the pre-irradiation, the diamond detector, which had not been irradiated on the day, was set up in the water tank, and the response to 100 MU was measured every 20 s. The depth-dose and profiles data were collected for various field sizes and depths. For all radiation types and field sizes, the depth-dose data of the diamond chamber showed identical curves to those of the ionization chambers. The profile of the diamond detector was very similar to those of the EDGE and SFD detectors, although the Semiflex and PinPoint chambers showed volume-averaging effects in the penumbrae region. The temperature dependency was within 0.7% in the range of 4-41°C. A dose of 900 cGy and 1200 cGy was needed to stabilize the chamber to the level within 0.5% and 0.2%, respectively. The PTW type 60019 SCDD detector showed suitable characteristics for radiation dosimetry, for relative dose, depth-dose and profile measurements for a wide range of field sizes. However, at least 1000 cGy of pre-irradiation will be needed for accurate measurements.


Assuntos
Radiometria/instrumentação , Fótons/uso terapêutico , Radiometria/classificação
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