RESUMO
The authors of the paper present three cases of nonclassical forms of congenital adrenal hyperplasia conditioned by 21 beta-hydroxylase deficiency occuring within the same family. They point out significant difficulties related to the detection of such anomalies, and they analyse in detail clinical symptoms occuring in this disease entity.
RESUMO
Acantosis Nigricans (AN) is a skin disease with rough or velvet areas present on neck or as hyperpigmented and wrinkled skin. AN often forms HAIR-AN syndrome consisted of hyperandrogenizm, insulin resistance and AN. We present AN and PCO syndrome in 13 yrs old girl treated by laparoscopic wedge resection. We concluded that laparoscopic procedure is a diagnostic measure and mode of PCO treatment. Decreased hyperandrogenizm resulted in AN appearance withdrawall.