1.
Org Lett
; 3(4): 553-6, 2001 Feb 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11178823
RESUMO
[reaction: see text] A remarkably general lithium heteroatom assisted TMSCN or TBSCN addition to aldehydes and ketones has been discovered. The process provides excellent selectivities and high rates. Conformationally constrained ketones such as camphor, fenchone, and nopinone give excellent diastereoselectivities with TMSCN. Reduction of 2 provided diastereopure amino alcohol 3 in good yield. alpha- and beta-Methyl cyclohexanones with TBSCN-LiOR afford high diastereoselectivities and yields.
2.
J Org Chem
; 65(19): 6283-7, 2000 Sep 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10987980
3.
Clin Rev Allergy Immunol
; 14(1): 7-35, 1996.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8866169