1.
Proc Natl Acad Sci U S A
; 97(16): 8815-21, 2000 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10922040
RESUMO
By exploiting the ability of Pseudomonas aeruginosa to infect a variety of vertebrate and nonvertebrate hosts, we have developed model systems that use plants and nematodes as adjuncts to mammalian models to help elucidate the molecular basis of P. aeruginosa pathogenesis. Our studies reveal a remarkable degree of conservation in the virulence mechanisms used by P. aeruginosa to infect hosts of divergent evolutionary origins.