Advances in artificial muscles: A brief literature and patent review.

Background: Artificial muscles are an active research area now. Methods: A bibliometric analysis was performed to evaluate the development of artificial muscles based on research papers and patents. A detailed overview of artificial muscles' scientific and technological innovation was presented from aspects of productive countries/regions, institutions, journals, researchers, highly cited papers, and emerging topics. Results: 1,743 papers and 1,925 patents were identified after retrieval in Science Citation Index-Expanded (SCI-E) and Derwent Innovations Index (DII). The results show that China, the United States, and Japan are leading in the scientific and technological innovation of artificial muscles. The University of Wollongong has the most publications and Spinks is the most productive author in artificial muscle research. Smart Materials and Structures is the journal most productive in this field. Materials science, mechanical and automation, and robotics are the three fields related to artificial muscles most. Types of artificial muscles like pneumatic artificial muscles (PAMs) and dielectric elastomer actuator (DEA) are maturing. Shape memory alloy (SMA), carbon nanotubes (CNTs), graphene, and other novel materials have shown promising applications in this field. Conclusion: Along with the development of new materials and processes, researchers are paying more attention to the performance improvement and cost reduction of artificial muscles.

Antibiotic resistant bacteria: A bibliometric review of literature.

Antibiotic-resistant bacteria (ARB) are a serious threat to the health of people and the ecological environment. With this problem becoming more and more serious, more countries made research on the ARB, and the research number has been sharply increased particularly over the past decade. Therefore, it is quite necessary to globally retrace relevant researches on the ARB published from 2010 to 2020. This will help researchers to understand the current research situation, research trends and research hotspots in this field. This paper uses bibliometrics to examine publications in the field of ARB from 2010 to 2020 that were retrieved from the Web of Science (WOS). Our study performed a statistical analysis of the countries, institutions, journals, authors, research areas, author keywords, Essential Science Indicators (ESI) highly cited papers, and ESI hotspots papers to provide an overview of the ARB field as well as research trends, research hotspots, and future research directions in the field. The results showed that the number of related studies is increasing year by year; the USA is most published in the field of ARB; China is the most active in this field in the recent years; the Chinese Acad Sci published the most articles; Sci. Total Environ. published the greatest number of articles; CM Manaia has the most contributions; Environmental Sciences and Ecology is the most popular research area; and "antibiotic resistance," "antibiotics," and "antibiotic resistance genes" were the most frequently occurring author keywords. A citation analysis showed that aquatic environment-related antibiotic resistance is a key research area in this field, while antimicrobial nanomaterial-related research is a recent popular topic.

Drug repositioning: A bibliometric analysis.

Drug repurposing has become an effective approach to drug discovery, as it offers a new way to explore drugs. Based on the Science Citation Index Expanded (SCI-E) and Social Sciences Citation Index (SSCI) databases of the Web of Science core collection, this study presents a bibliometric analysis of drug repurposing publications from 2010 to 2020. Data were cleaned, mined, and visualized using Derwent Data Analyzer (DDA) software. An overview of the history and development trend of the number of publications, major journals, major countries, major institutions, author keywords, major contributors, and major research fields is provided. There were 2,978 publications included in the study. The findings show that the United States leads in this area of research, followed by China, the United Kingdom, and India. The Chinese Academy of Science published the most research studies, and NIH ranked first on the h-index. The Icahn School of Medicine at Mt Sinai leads in the average number of citations per study. Sci Rep, Drug Discov. Today, and Brief. Bioinform. are the three most productive journals evaluated from three separate perspectives, and pharmacology and pharmacy are unquestionably the most commonly used subject categories. Cheng, FX; Mucke, HAM; and Butte, AJ are the top 20 most prolific and influential authors. Keyword analysis shows that in recent years, most research has focused on drug discovery/drug development, COVID-19/SARS-CoV-2/coronavirus, molecular docking, virtual screening, cancer, and other research areas. The hotspots have changed in recent years, with COVID-19/SARS-CoV-2/coronavirus being the most popular topic for current drug repurposing research.

Dyslexia: A Bibliometric and Visualization Analysis.

Dyslexia is a disorder characterized by an impaired ability to understand written and printed words or phrases. Epidemiological longitudinal data show that dyslexia is highly prevalent, affecting 10-20% of the population regardless of gender. This study aims to provide a detailed overview of research status and development characteristics of dyslexia from types of articles, years, countries, institutions, journals, authors, author keywords, and highly cited papers. A total of 9,166 publications have been retrieved from the Social Sciences Citation Index (SSCI) and Science Citation Index Expanded (SCI-E) from 2000 to 2021. The United States of America, United Kingdom, and Germany were the top three most productive countries in terms of the number of publications. China, Israel, and Japan led the Asia research on dyslexia. University of Oxford had the most publications and won first place in terms of h-index. Dyslexia was the most productive journal in this field and Psychology was the most used subject category. Keywords analysis indicated that "developmental dyslexia," "phonological awareness," children and fMRI were still the main research topics. "Literacy," "rapid automatized naming (RAN)," "assessment," "intervention," "meta-analysis," "Chinese," "executive function," "morphological awareness," "decoding," "dyscalculia," "EEG," "Eye tracking," "rhythm," "bilingualism," and "functional connectivity" might become the new research hotspots.

Bibliometric analysis of the 100 top-cited articles on immunotherapy of urological cancer.

PURPOSE: To highlight the scientific progress in immunotherapy of urological cancer by identifying and analyzing the 100 top-cited (T100) articles from the last 15 years. METHODS: Papers in immunotherapy of urological cancer were identified from Clarivate Web of Science Core Collection database. Data of the T100 articles and papers published in recent 2 years, including citations, topic, year of publication, country of origin, institution and authorship, were extracted and analyzed. RESULTS: Of the T100 articles, the citation number ranged from 7387 to 183 with a mean of 590.66. The USA led the field with 80 T100 articles and 53097 citations. Pro Sharma P from MD Anderson Cancer Center was at the top of list with 8 T100 articles (3 as first author and 6 as corresponding author). Memorial Sloan Kettering Cancer Center ranked first with 26 T100 articles and 22573 citations, followed by Johns Hopkins University with 21 T100 articles and 25095 citations. Forty-nine T100 articles were related to the renal cancer, followed by prostate cancer (29), bladder cancer (13) and urothelial cancer (13). According to the type of immunotherapy, most T100 articles were related to ICI (55 articles) and vaccine (19 articles). CONCLUSIONS: It is the first bibliometric analysis to identify the T100 articles on immunotherapy of urological cancer. The USA made great contribution in the field of immunotherapy related to urological cancer. Renal, bladder and prostate cancers were the major organs treated by immunotherapy especially by ICIs and vaccines. The multiple aspects of ICIs research in renal and bladder cancer and the neoantigen-based vaccine therapy will be hotspots for future research.

Recent Trends in Sedentary Time: A Systematic Literature Review.

This paper systematically reviews and synthesizes the relevant literature on sedentary time research. A bibliometric analysis was conducted to evaluate the publications from 2010 to 2020 in the Web of Science (WoS) core collection database. Derwent Data Analyzer software was used for the cleaning, mining, and visualization of the data. Historical trends of the topics, main contributors, leading countries, leading institutions, leading research areas, and journals were explored. A total of 3020 publications were studied. The United States, the United Kingdom, and Australia are the three most productive countries. The Australian institution Baker Heart and Diabetes Institute led the list of productive institutions, and Ekelund U published the most papers. Sedentary time raised the concerns of scholars from 106 research areas, and public health was the dominant field. Physical activity, accelerometer, children, and obesity were the most frequently used keywords. The findings suggest that sedentary time is rapidly emerging as a global issue that has detrimental effects on public health. The hotspots shifted in the past 10 years, and COVID-19 was the most popular topic of sedentary time research.

Energy Storage Ceramics: A Bibliometric Review of Literature.

Energy storage ceramics is among the most discussed topics in the field of energy research. A bibliometric analysis was carried out to evaluate energy storage ceramic publications between 2000 and 2020, based on the Web of Science (WOS) databases. This paper presents a detailed overview of energy storage ceramics research from aspects of document types, paper citations, h-indices, publish time, publications, institutions, countries/regions, research areas, highly cited papers, and keywords. A total of 3177 publications were identified after retrieval in WOS. The results show that China takes the leading position in this research field, followed by the USA and India. Xi An Jiao Tong Univ has the most publications, with the highest h-index. J.W. Zhai is the most productive author in energy storage ceramics research. Ceramics International, Journal of Materials Science-Materials in Electronics, and the Journal of Alloys and Compounds are the most productive journals in this field, and materials science-multidisciplinary is the most frequently used subject category. Keywords, highly cited papers, and the analysis of popular papers indicate that, in recent years, lead-free ceramics are prevalent, and researchers focus on fields such as the microstructure, thin films, and phase transition of ceramics.

A bibliometric analysis of income and cardiovascular disease: Status, Hotspots, Trends and Outlook.

BACKGROUND: Income is 1 of the socio-economic indicators and could directly influence the health outcomes of cardiovascular disease (CVD). The relationship between income and CVD has attracted more and more scholars' attention in the past 20 years. METHODS: To study the current research dynamics of this field, a bibliometric analysis was conducted to evaluate the publications from 1990 to 2018 based on the Science Citation Index Expanded database. By using the Derwent Date Analyzer software, the following aspects were explored: RESULTS:: The USA ranked first in this field, followed by UK and Canada in terms of number of publications. As for institutions, Harvard University took the leading place in the number of publications, as well as the h-index. Plos One had the most publications and "health" was the most frequent used keyword. The leading research area was "public environmental occupational health". CONCLUSIONS: In conclusion, the elderly, the children and the puerpera were the main study population in this field and "disease prevention" was the main study direction. The most concerned health issues in this field were "obesity" and "diet". There might be a lack of articles that explore the associations between income and CVD with a global perspective. Articles on this content are urgently warranted.

Intimate Partner Violence: A Bibliometric Review of Literature.

Intimate partner violence (IPV) is a worldwide public health problem. Here, a bibliometric analysis is performed to evaluate the publications in the Intimate Partner Violence (IPV) field from 2000 to 2019 based on the Science Citation Index (SCI) Expanded and the Social Sciences Citation Index (SSCI) databases. This work presents a detailed overview of IPV from aspects of types of articles, citations, h-indices, languages, years, journals, institutions, countries, and author keywords. The results show that the USA takes the leading position in this research field, followed by Canada and the U.K. The University of North Carolina has the most publications and Harvard University has the first place in terms of h-index. The London School of Hygiene and Tropical Medicine leads the list of average citations per paper. The Journal of Interpersonal Violence, Journal of Family Violence and Violence Against Women are the top three most productive journals in this field, and Psychology is the most frequently used subject category. Keywords analysis indicates that, in recent years, most research focuses on the research fields of "child abuse", "pregnancy", "HIV", "dating violence", "gender-based violence" and "adolescents".

Eosinophilic fasciitis associated with generalized morphea and IgA nephropathy.

Eosinophilic fasciitis (EF) is a rare connective tissue disease characterized by increased peripheral blood eosinophils and diffuse fasciitis, generalized morphea (GM) is a subtype of localized scleroderma, and IgA nephropathy is a chronic glomerulonephritis caused by abnormal deposition of IgA in the mesangial area of the glomeruli. We describe a 49-year-old male patient with hard skin, cutaneous hyperpigmentation, and proteinuria. The patient had suffered from a long disease course of hard skin, while urine protein was newly detected. Finally, the clinical presentation and physical examination, limb MRI, skin biopsy, and renal biopsy confirmed the diagnosis of eosinophilic fasciitis associated with generalized morphea and IgA nephropathy. This case is the first report of EF associated with GM and IgA nephropathy.

Metastatic castration-resistant prostate cancer: Academic insights and perspectives through bibliometric analysis.

BACKGROUND: In recent years, metastatic castration-resistant prostate cancer (MCRPC) and studies related to MCRPC have drawn global attention. The main objective of this bibliometric study was to provide an overview of MCRPC, explore clusters and trends in research and investigate the future direction of MCRPC research. METHODS: A total of 4089 publications published between 1979 and 2018 were retrieved from the Web of Science (WoS) Core Collection database. Different aspects of MCRPC research, including the countries/territories, institutions, journals, authors, research areas, funding agencies and author keywords, were analyzed. RESULTS: The number of annual MCRPC publications increased rapidly after 2010. American researchers played a vital role in this increase, as they published the most publications. The most productive institution was Memorial Sloan Kettering Cancer Center. De Bono, JS (the United Kingdom [UK]) and Scher, HI (the United States of America [USA]) were the two most productive authors. The National Institutes of Health (NIH) funded the largest number of published papers. Analyses of keywords suggested that therapies (abiraterone, enzalutamide, etc.) would attract global attention after US Food and Drug Administration (FDA) approval. CONCLUSIONS: Developed countries, especially the USA, were the leading nations for MCRPC research because of their abundant funding and frequent international collaborations. Therapy was one of the most vital aspects of MCRPC research. Therapies targeting DNA repair or the androgen receptor (AR) signing pathway and new therapies especially prostate-specific membrane antigen (PSMA)-based radioligand therapy (RLT) would be the next focus of MCRPC research.

Corrections to "Academic Review and Perspectives on Robotic Exoskeletons".

We have noticed some errors in the above-titled paper (DOI: 10.1109/TNSRE.2019.2944655) [1].

The 100 most-cited articles in urological surgery: A bibliometric analysis.

BACKGROUND: The purpose of this bibliometric analysis was to identify and assess the 100 most-cited articles (T100 articles) on urological surgery. METHODS: The Web of Science (WoS) Core Collection database was used to investigate the T100 articles in the field of urological surgery. Different aspects of the T100 articles, including the countries, journals, authors, and topics, were analyzed. RESULTS: The number of citations of T100 articles published between 1989 and 2016 ranged from 334 to 2189. The T100 articles originated from 28 countries, with more than half originating from the USA (n = 80). Professor Bill-Axelson A from Uppsala University Hospital published the largest number of T100 articles as the first author (4) and as a coauthor (1). The Memorial Sloan Kettering Cancer Center from the USA is the top institution with the most T100 articles in the field of urological surgery. The special journal Journal of Urology published 41 of the T100 articles, which had a total of 19780 citations. CONCLUSIONS: Our study analyzed the 100 most-cited articles in the field of urological surgery. The USA is the dominant country in terms of the number of T100 articles, scientists and institutions. Surgery related to urological cancer has garnered the most academic attention, especially prostate cancer and renal cancer.

Academic Review and Perspectives on Robotic Exoskeletons.

Since the first robotic exoskeleton was developed in 1960, this research field has attracted much interest from both the academic and industrial communities resulting in scientific publications, prototype developments and commercialized products. In this article, to document the progress in and current status of this field, we performed a bibliometric analysis. This analysis evaluated the publications in the field of robotic exoskeletons from 1990 to July 2019 that were retrieved from the Science Citation Index Expanded database. The bibliometric analyses were presented in terms of author keywords, year, country, institution, journal, author, and the citation. Results show that currently the United States has taken the leading position in this field and has built the largest collaborative network with other countries. The Massachusetts Institute of Technology (MIT) made the greatest contribution to the field of robotic exoskeleton investigations in terms of the number of publications, average citations per publication and the h-index. In addition, the Journal of NeuroEngineering and Rehabilitation ranks first among the top 20 academic journals in terms of the number of publications related to robotic exoskeletons during the period investigated. Author keyword analysis indicates that most research has focused on rehabilitation robotics. Biomedical engineering, rehabilitation and the neurosciences are the most common disciplines conducting research in this area according to the Web of Science (WoS). Our study comprehensively assesses the current research status and collaboration network of robotic exoskeletons, thus helping researchers steer their projects or locate potential collaborators.

Carotid contrast-enhanced ultrasonographic assessment of disease activity in Takayasu arteritis.

AIMS: To investigate the usefulness of carotid contrast-enhanced ultrasound (CEUS) in assessment of disease activity in patients with Takayasu arteritis (TA). METHODS AND RESULTS: After screening 219 CEUS records from 124 consecutive patients followed at our clinic between October 2014 and May 2018, data were analysed from 159 carotid CEUS from 86 patients diagnosed with Type I TA. Patients were categorized based on disease activity according to National Institutes of Health criteria into two groups: active disease group (92 CEUS) and non-active disease group (67 CEUS). The enhanced intensity of carotid artery wall: (i) was higher in active disease group than in non-active disease group (3.09 ± 1.67 dB vs. 1.44 ± 1.29 dB, P < 0.0001, respectively); and (ii) had a high predictive value for TA disease activity with area under the curve (AUC) of 86.3% [95% confidence interval (CI) 79.7-92.9], sensitivity of 88.0%, and specificity of 79.1%. The latter AUC was not significantly affected (P > 0.05) when erythrocyte sedimentation rate, C-reactive protein level, or arterial wall thickness were added to assessment of disease activity in TA. CONCLUSION: Carotid vascularization by CEUS, as sole inflammatory marker, had a high predictive value for disease activity in Type I TA.

Soft Robotics: Academic Insights and Perspectives Through Bibliometric Analysis.

Soft robotics is of growing interest in the robot community as well as in public media, and there is an increase in the quality and quantity of publications related to this topic. To formally elaborate this growth, we have used a bibliometric analysis to evaluate the publications in the field from 1990 to 2017 based on the Science Citation Index Expanded database. We present a detailed overview and discussion based on keywords, citation, h-index, year, journal, institution, country, author, and review articles. The results show that the United States takes the leading position in this research field, followed by China and Italy. Harvard University has the most publications, high average number of citations per publication and the highest h-index. IEEE Transactions on Robotics ranks first among the top 20 academic journals publishing articles related to this field, whereas Soft Robotics holds the top position in journals categorized with "ROBOTICS." Actuator, fabrication, control, material, sensing, simulation, bionics, stiffness, modeling, power, motion, and application are the hot topics of soft robotics. Smart materials, bionics, morphological computation, and embodiment control are expected to contribute to this field in the future. Application and commercialization appear to be the initial driving force and final goal for soft robots.

Bis(2-chloro-5-methylpyridine-kappaN)bis(nitrato-kappa(2)O,O')copper(II).

In the molecule of the title compound, [Cu(NO(3))(2)(C(6)H(6)ClN)(2)], the Cu atom lies on an inversion centre and is six-coordinated by two pyridine N atoms and four nitrate O atoms in trans positions. The nitrate acts as an unsymmetrical bidentate ligand. The coordination geometry is octahedral, with the Cu-N and the two Cu-O distances being 1.9939 (16), 2.0246 (16) and 2.4866 (19) A, respectively. There are five types of C-H.O hydrogen bonds. Two of these generate two-dimensional molecular networks in the direction of the a axis, and the others connect adjacent molecular networks.