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J Agric Food Chem ; 62(1): 192-7, 2014 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-24313233

RESUMO

Many studies have utilized a variety of methods to induce obesity in rodents, but they often received inconsistent results. The present study intended to use resistant maltodextrin (RMD) as a means to investigate the variations in its efficacy on body fat accumulation under the influence of four high-fat (HF) models of 23% or 40% total fat, comprising soybean oil, lard, and/or condensed milk. Results indicated that integrating condensed milk into the diets could help increase diet intake, boost energy intake, increase weight gain, and enhance fat formation. Supplementation of RMD (2.07 g/kg) notably reduced total body fat levels in three HF models, with the exception of a condensed-milk-added 40%-fat diet that may have misrepresented the functions of RMD. The uses of the 23% HF diets, with and without milk, and the milk-free 40% HF diet were therefore recommended as suitable models for antiobesity evaluations of RMD, or other fiber-rich products.


Assuntos
Tecido Adiposo/efeitos dos fármacos , Obesidade/tratamento farmacológico , Polissacarídeos/administração & dosagem , Tecido Adiposo/metabolismo , Animais , Dieta Hiperlipídica/efeitos adversos , Modelos Animais de Doenças , Ingestão de Energia/efeitos dos fármacos , Humanos , Masculino , Obesidade/metabolismo , Ratos , Ratos Sprague-Dawley
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