RESUMO
BACKGROUND: Tinea capitis is caused by dermatophyte fungi that utilize keratin as a nutrient source. Scalp erythema, scaling, andcrusting are typical signs of this disease. Although most commonly seen in prepubescent children, tinea capitis can occur in adults. RESULTS: Endothrix tinea capitis owing to Trichophyton tonsurans commonly produces generalized scaling and localized perifollicular inflammation reminiscent of lichen planopilaris. Ectothrix tinea capitis owing to Microsporum sp. produces well- demarcated erythematous plaques suggestive of psoriasis. H&E stained biopsy specimens, KOH preparations or fungal cultures will confirm the diagnosis. CONCLUSION: Because of a low index of suspicion for tinea capitis in adults with scaling and alopecia, diagnosis and appropriate treatment are often delayed. Resistance to treatment for seborrheic dermatitis or psoriasis should prompt a KOH, fungal culture orbiopsy to confirm the diagnosis of tinea capitis and initiate systemic antifungal agents.
Assuntos
Pele/patologia , Tinha do Couro Cabeludo/patologia , Idoso , Antifúngicos/uso terapêutico , Feminino , Humanos , Naftalenos/uso terapêutico , Terbinafina , Tinha do Couro Cabeludo/diagnóstico , Tinha do Couro Cabeludo/tratamento farmacológicoRESUMO
We present a rare case of necrotizing sarcoid granulomatosis (NSG) with skin and pulmonary involvement. NSG with extrapulmonary involvement occurs infrequently, and reports involving skin manifestations in NSG are even more rare.
Assuntos
Granulomatose com Poliangiite/patologia , Sarcoidose Pulmonar/patologia , Dermatopatias/patologia , Feminino , Granulomatose com Poliangiite/terapia , Humanos , Pessoa de Meia-Idade , Sarcoidose Pulmonar/terapia , Dermatopatias/terapiaRESUMO
Malignancy is a well-known cause of cutaneous vasculitis. The occurrence of neoplasia and Henoch-Schönlein purpura (HSP) is rare and poorly understood in adults. A total of 31 cases have been reported in the world literature of adult malignancy-associated HSP. Patients were overwhelmingly male (94%) with a mean age of 60 years and presented predominantly with solid tumors (61%). The most frequent tumors were lung (nonsmall-cell) (n = 8), multiple myeloma (n = 5), prostate (n = 5), and non-Hodgkin's lymphoma (n = 3). The majority of patients (55%) developed HSP within 1 month of cancer diagnosis or detection of metastases. We present 3 cases of adults who, in the absence of known precipitating factors, developed HSP within 2 months of diagnosis of a solid tumor or metastases. We recommend that adults, especially older men who present with unexplained HSP, be evaluated for occult neoplasm. We also advise that patients with a known history of malignancy who present with HSP be evaluated for metastatic disease.
