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1.
Diabetes Res Clin Pract ; 171: 108540, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33212116

RESUMO

Among 100 Indonesian adults with type 2 diabetes having vision-threatening diabetic retinopathy, less than 25% of individuals had appropriate treatment within 12 months from their initial screening due to lack of information about the treatment cost (88%), no permission from family member (77.3%) and having no eye complaint (77%).


Assuntos
Complicações do Diabetes/complicações , Retinopatia Diabética/diagnóstico , Serviços de Saúde/normas , Estudos de Coortes , Feminino , Humanos , Indonésia , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Estudos Prospectivos
2.
Diabetes Care ; 41(11): 2377-2384, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30213883

RESUMO

OBJECTIVE: To investigate the associations of estimated resting metabolic rate (RMR), body fat (BF), subcutaneous fat (SCF), visceral fat (VF), fat-free mass (FFM) percentage, BMI, and waist circumference (WC) with diabetic retinopathy (DR) in Indonesian adults with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a community-based cross-sectional study of 1,184 subjects with type 2 diabetes. DR was assessed from fundus photography and categorized as mild, moderate nonproliferative DR (NPDR), and vision-threatening DR (VTDR). RMR and body composition parameters were measured using automated body composition scan. Logistic regression with semipartial correlation analysis was used. RESULTS: DR and VTDR were present in 43.1 and 26.3% of participants, respectively. After adjustment for age, sex, diabetes duration, fasting glucose, systolic blood pressure, smoking, diabetic ulcer, and use of combined diabetes treatment, per SD increase in RMR (odds ratio [OR] 2.60 [95% CI 2.19-3.07]; P < 0.001) was associated with DR, while per SD increases in BF (0.66 [95% CI 0.56-0.78]; P < 0.001), FFM (0.69 [0.57-0.84]; P < 0.001), VF (0.77 [0.67-0.88]; P < 0.001), BMI (0.83 [0.73-0.94]; P = 0.004), and WC (0.81 [0.73-0.91]; P < 0.001) were inversely associated with presence of DR. Similar associations were found for VTDR. Among all variables, RMR had the largest contribution to the variance in the DR model (39%). CONCLUSIONS: In this study, RMR and body composition measures were strongly associated with and contributed considerably to the presence and severity of DR. These findings, if confirmed, suggest that RMR and body composition may be strong markers that represent actual metabolic state in the pathophysiology of DR.


Assuntos
Metabolismo Basal/fisiologia , Composição Corporal/fisiologia , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/diagnóstico , Retinopatia Diabética/diagnóstico , Descanso/fisiologia , Adulto , Idoso , Estudos Transversais , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/metabolismo , Retinopatia Diabética/epidemiologia , Retinopatia Diabética/metabolismo , Retinopatia Diabética/patologia , Progressão da Doença , Feminino , Humanos , Indonésia/epidemiologia , Masculino , Pessoa de Meia-Idade , Prognóstico , Fatores de Risco , Índice de Gravidade de Doença
3.
Ophthalmic Epidemiol ; 24(1): 48-56, 2017 02.
Artigo em Inglês | MEDLINE | ID: mdl-28032809

RESUMO

PURPOSE: There are no available data about diabetic retinopathy (DR) in the Indonesian population. This report summarizes the rationale and study design of the Jogjakarta Eye Diabetic Study in the Community (JOGED.COM), a community-based study to estimate the prevalence and risk factors of DR in persons with type 2 diabetes in Jogjakarta, Indonesia. METHODS: The JOGED.COM aimed to examine a cross-sectional sample of 1200 persons with type 2 diabetes aged 30 years and older residing in the study area. We identified 121 community health centers (CHCs) in Jogjakarta and listed 35 CHCs with non-communicable diseases facilities. Multi-stage, clustered random sampling was used to select 22 CHCs randomly. We included CHCs with coverage population >30,000, and excluded those classified as 100% rural. Lists of persons with diabetes confirmed by their family physician were provided from each CHC. Examinations procedures included detailed interviews, general and eye examinations, anthropometry and body composition scan, and dilated fundus photography. RESULTS: We collaborated with local health authorities, family physicians, and local health practitioners in the recruitment phase. A total of 1435 invitations were distributed, and 1184 people (82.5%) with type 2 diabetes participated in this study, of whom 1138 (79.3%) had completed data with gradable retinal images. CONCLUSIONS: JOGED.COM is the first epidemiologic study of DR in an Indonesian population. This study will provide key information about the prevalence and risk factors of DR in the community. These data are very important for future health promotion programs to reduce the burden of DR in the population.


Assuntos
Diabetes Mellitus Tipo 2/complicações , Retinopatia Diabética/epidemiologia , Adulto , Distribuição por Idade , Idoso , Cegueira/epidemiologia , Cegueira/etiologia , Análise por Conglomerados , Estudos Transversais , Retinopatia Diabética/complicações , Feminino , Humanos , Indonésia/epidemiologia , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco
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