RESUMO
Case report of a patient with a giant ovarian cyst. On the basis of literature data, surgery and histology problems, as well as oncological therapy are discussed.
Assuntos
Cistadenocarcinoma Mucinoso/cirurgia , Neoplasias Ovarianas/cirurgia , Quimioterapia Adjuvante , Cistadenocarcinoma Mucinoso/tratamento farmacológico , Cistadenocarcinoma Mucinoso/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Ovarianas/tratamento farmacológico , Neoplasias Ovarianas/patologiaAssuntos
Histiocitoma Fibroso Benigno/etiologia , Neoplasias Induzidas por Radiação/etiologia , Radioterapia de Alta Energia/efeitos adversos , Neoplasias Torácicas/etiologia , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias da Mama/radioterapia , Feminino , Histiocitoma Fibroso Benigno/tratamento farmacológico , Humanos , Pessoa de Meia-Idade , Neoplasias Torácicas/tratamento farmacológicoRESUMO
Extravasation of doxorubicin (DXR) from a dorsal hand vein is described. At 28 days following this event, high dermal concentrations of DXR were still present, not only at the injection site (1.7 X 10(-6) M X g-1) but also at a distance of 5 cm (0.4 X 10(-6) m X g-1. This long persistence of DXR in the skin necessitates ample excision of the skin following severe extravasation of the drug.
Assuntos
Doxorrubicina/efeitos adversos , Úlcera Cutânea/induzido quimicamente , Adulto , Doxorrubicina/administração & dosagem , Doxorrubicina/análise , Feminino , Humanos , Injeções Intravenosas/efeitos adversos , Necrose/induzido quimicamente , Úlcera Cutânea/metabolismo , Fatores de TempoRESUMO
A 25-year-old man presented with a malignant teratoma of the right testicle. After orchidectomy, the results of the surgical staging procedure were negative. Although pulmonary metastasis did not occur, massive bone marrow involvement with a bleeding tendency and hypercalcemic nephropathy developed. The response to chemotherapy was excellent, but after the attainment of a complete remission the patient developed carcinomatous leptomeningitis, which was confirmed at autopsy as cause of death.
