RESUMO
Langerhans cell histiocytosis is a disorder characterized by the proliferation of histiocytes of the mononuclear phagocyte system. Cutaneous Langerhans cell histiocytosis can develop as a solitary lesion or more frequently as part of a multisystem disease. This report describes a case of cutaneous Langerhans cell histiocytosis affecting the eyelids, resulting in a coloboma-like defect. The clinical features and management are discussed.
Assuntos
Doenças Palpebrais/etiologia , Histiocitose de Células de Langerhans/complicações , Dermatopatias/complicações , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Pré-Escolar , Terapia Combinada , Doenças Palpebrais/patologia , Doenças Palpebrais/terapia , Seguimentos , Glucocorticoides/uso terapêutico , Histiocitose de Células de Langerhans/patologia , Histiocitose de Células de Langerhans/terapia , Humanos , Células de Langerhans/patologia , Masculino , Procedimentos Cirúrgicos Oftalmológicos , Dermatopatias/patologia , Dermatopatias/terapiaRESUMO
Cholesteatomas, also known as epidermal cholesterol cysts, are unusual cystic lesions containing numerous cholesterol clefts that are usually found in the orbits in the ophthalmic setting. This report describes the clinical and microscopic features of an unusual cholesteatoma in the eyelid.
Assuntos
Colesteatoma/diagnóstico , Colesterol/metabolismo , Neoplasias Palpebrais/diagnóstico , Colesteatoma/metabolismo , Colesteatoma/cirurgia , Diagnóstico Diferencial , Neoplasias Palpebrais/metabolismo , Neoplasias Palpebrais/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
PURPOSE: To report the clinicopathologic features of a solitary superficial angiomyxoma arising in the eyelid. DESIGN: Case report. METHODS: A retrospective review of the clinical and pathologic features of a patient with solitary superficial angiomyxoma in the eyelid. RESULTS: A 47-year-old male presented with a right upper lid mass for 6 months. Excisional biopsy was performed, and microscopic examination revealed a tumor comprising loose spindle or stellate-shaped cells in myxoid stroma sprinkled with small numbers of neutrophils. The tumor cells were negative for smooth muscle actin, desmin, S-100 protein, and CD34 on immunostaining. CONCLUSIONS: Ophthalmologists should be aware of superficial angiomyxoma as a rare cutaneous tumor with a tendency for local recurrence. Multiple lesions and occurrence in the external ear can be associated with the Carney's complex.
