Structured line illumination Raman microscopy.

In the last couple of decades, the spatial resolution in optical microscopy has increased to unprecedented levels by exploiting the fluorescence properties of the probe. At about the same time, Raman imaging techniques have emerged as a way to image inherent chemical information in a sample without using fluorescent probes. However, in many applications, the achievable resolution is limited to about half the wavelength of excitation light. Here we report the use of structured illumination to increase the spatial resolution of label-free spontaneous Raman microscopy, generating highly detailed spatial contrast from the ensemble of molecular information in the sample. Using structured line illumination in slit-scanning Raman microscopy, we demonstrate a marked improvement in spatial resolution and show the applicability to a range of samples, including both biological and inorganic chemical component mapping. This technique is expected to contribute towards greater understanding of chemical component distributions in organic and inorganic materials.

Note: Light output enhanced fast response and low afterglow 6Li glass scintillator as potential down-scattered neutron diagnostics for inertial confinement fusion.

The characteristics of an APLF80+3Ce scintillator are presented. Its sufficiently fast decay profile, low afterglow, and an improved light output compared to the recently developed APLF80+3Pr, were experimentally demonstrated. This scintillator material holds promise for applications in neutron imaging diagnostics at the energy regions of 0.27 MeV of DD fusion down-scattered neutron peak at the world's largest inertial confinement fusion facilities such as the National Ignition Facility and the Laser Mégajoule.