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1.
Health Sociol Rev ; : 1-18, 2023 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-36759339

RESUMO

There are numerous ways that researchers can creatively approach social research and translation. This article discusses elements from the first stages of a novel project that centres social research translation in the form of a public exhibition. 'Creative Approaches to Health Information Ecologies' is a project by a multidisciplinary research team in collaboration with an Australian health consumer organisation. The project uses creative workshop methods to explore how people learn, think, and feel about their bodies and health states, and brings attention to the significance of communities, places, spaces, objects, and other living things - the 'ecologies' of health information. It then builds on these insights to create an interactive exhibition of materials designed for public engagement. This reflexive article unpacks how this creative translation-centred collaboration contributed to the make-up of the project team, the project's research methods, and the process of making exhibition materials. We discuss what the research team learned from the process about creative collaboration, research-creation, and research translation.

2.
Int J Qual Methods ; 21: 16094069221078376, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35309898

RESUMO

Restrictions on physical movements and in-person encounters during the COVID-19 crisis confronted many qualitative researchers with challenges in conducting and completing projects requiring face-to-face fieldwork. An exploration of engaging in what we term 'agile research' in such circumstances can offer novel methodological insights for researching the social world. In this article, we discuss the changes we made to our ethnographic fieldwork in response to the introduction of a national lockdown to contain the spread of the novel coronavirus. The 'Living with Personal Data' project, based in Sydney, Australia, and designed well before the advent of COVID-19, explores a diverse range of people's feelings, practices and understandings concerning home-based digital devices and the personal digital data generated with their use. Using a video ethnography 'home tour' and an elicitation technique involving hand-drawn maps of people's homes, digital devices and the personal data generated with and through these devices, this approach was designed to elicit the sensory, affective and relational elements of people's digital device and personal data use at home. The fieldwork had just commenced when stay-at-home and physical distancing orders were suddenly introduced. Our article builds on and extends a growing body of literature on conducting fieldwork in the difficult conditions of the extended COVID-19 crisis by detailing our experiences of very quickly converting an ethnographic study that was planned to be in-person to a remote approach. We describe the adaptations we made to the project using video-call software and discuss the limits and opportunities presented by this significant modification.

4.
Elife ; 62017 08 15.
Artigo em Inglês | MEDLINE | ID: mdl-28829740

RESUMO

An 'interactome' screen of all Drosophila cell-surface and secreted proteins containing immunoglobulin superfamily (IgSF) domains discovered a network formed by paralogs of Beaten Path (Beat) and Sidestep (Side), a ligand-receptor pair that is central to motor axon guidance. Here we describe a new method for interactome screening, the Bio-Plex Interactome Assay (BPIA), which allows identification of many interactions in a single sample. Using the BPIA, we 'deorphanized' four more members of the Beat-Side network. We confirmed interactions using surface plasmon resonance. The expression patterns of beat and side genes suggest that Beats are neuronal receptors for Sides expressed on peripheral tissues. side-VI is expressed in muscle fibers targeted by the ISNb nerve, as well as at growth cone choice points and synaptic targets for the ISN and TN nerves. beat-V genes, encoding Side-VI receptors, are expressed in ISNb and ISN motor neurons.


Assuntos
Proteínas de Drosophila/genética , Drosophila melanogaster/metabolismo , Cones de Crescimento/metabolismo , Proteínas de Membrana/genética , Neurônios Motores/metabolismo , Músculos/metabolismo , Proteínas do Tecido Nervoso/genética , Sistema Nervoso/metabolismo , Animais , Anticorpos/química , Bioensaio , Biologia Computacional , Proteínas de Drosophila/metabolismo , Drosophila melanogaster/genética , Drosophila melanogaster/crescimento & desenvolvimento , Drosophila melanogaster/ultraestrutura , Embrião não Mamífero , Corantes Fluorescentes/química , Regulação da Expressão Gênica no Desenvolvimento , Cones de Crescimento/ultraestrutura , Proteínas de Membrana/metabolismo , Neurônios Motores/ultraestrutura , Músculos/ultraestrutura , Proteínas do Tecido Nervoso/metabolismo , Sistema Nervoso/crescimento & desenvolvimento , Sistema Nervoso/ultraestrutura , Ficoeritrina/química , Filogenia , Mapeamento de Interação de Proteínas/métodos , Isoformas de Proteínas/genética , Isoformas de Proteínas/metabolismo , Transdução de Sinais
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