RESUMO
OBJECTIVES: Genetic anomalies are one of many conditions causing infertility. DESIGN: The aim of the study was to define the frequency of numerical chromosome aberrations in infertile married couples. MATERIALS AND METHODS: Metaphasal chromosomes were analysed by G-T-G stration in 650 patients, i.e. 325 married couples. Chromosomes for testing had been obtained from peripheral blood lymphocytes. RESULTS: Of all women and men, numerical chromosome anomalies were found in 14 married couples (4.1%). The aberrations were connected with female factors in 8 couples (2.3%), and with male factors in 6 (1.8%). CONCLUSIONS: Results of the study indicate that diagnostic procedure for infertility should preferably include cytogenetic examinations as well.
Assuntos
Aberrações Cromossômicas/genética , Infertilidade Feminina/genética , Infertilidade Masculina/genética , Casamento , Transtornos Cromossômicos , Feminino , Humanos , Infertilidade Feminina/diagnóstico , Infertilidade Masculina/diagnóstico , Cariotipagem , Síndrome de Klinefelter/diagnóstico , Síndrome de Klinefelter/genética , Linfócitos/citologia , Masculino , Metáfase/genética , Fenótipo , Estudos Retrospectivos , Síndrome de Turner/diagnóstico , Síndrome de Turner/genéticaRESUMO
Our objective in this study was to compare the parameters of the acid-base balance in the capillary blood 60 minutes after delivery with the antenatal cardiotocographic computer analysis. Our study included 64 infants delivered vaginally on term. The basic criterion to classify into the examined group and control group was a pH result of the capillary blood equal to 7.30. In the examined group there were 34 cases and 30 in the control group. Retrospective analysis of cardiotocographs was carried out. The determination was made of pH, pCO2, pO2, HCO3, SBE and SAT in the capillary blood. The analysed material showed a very good negative correlation between a pH value in the examined group and a short-term variability (STV) (r = 0.95 at p < 0.001). It was concluded that there is a strong relationship between elements of computer-aided cardiotocographic monitoring and abnormalities in the acid-base balance and condition of the infant.
