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2.
Forsch Komplementmed ; 17(5): 271-3, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20980767

RESUMO

Betulin, a pentacyclic triterpene, is the main constituent of the outer bark of birches (Betula alba). In recent years, anti-microbial, anti-inflammatory and differentiation-promoting effects of betulin have been described. A betulin-based emulsion without preservatives and detergent emulsifiers can be prepared from birch bark extract. We report the successful treatment with betulin emulsion of a severe necrotising herpes zoster in an immunosuppressed patient who had not responded to a conventional topical treatment. The betulin emulsion was directly applied to the wounds without causing any side effects. The presented case report demonstrates impressive skin tolerance and wound-healing properties of the betulin emulsion. These should be further evaluated.


Assuntos
Betula , Herpes Zoster/tratamento farmacológico , Triterpenos/uso terapêutico , Herpes Zoster/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Casca de Planta/química , Dermatopatias/tratamento farmacológico , Dermatopatias/patologia , Resultado do Tratamento , Triterpenos/isolamento & purificação , Cicatrização
3.
J Dtsch Dermatol Ges ; 8(10): 788-96, 2010 Oct.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-20707875

RESUMO

Plant extracts and isolated compounds are increasingly used in cosmetics and food supplements to improve skin conditions. We first introduce the positive plant monographs with dermatological relevance of the former German Commission E. Subsequently clinical studies with botanicals for atopic dermatitis, psoriasis, acne, condylomata acuminata and herpes simplex are discussed. The best studies have been conducted with atopic dermatitis and psoriasis patients. Mahonia aquifolium, Hypericum perforatum, Glycyrrhiza glabra and certain traditional Chinese therapies have been shown to be effective in the treatment of atopic dermatitis. Mahonia aquifolium, Indigo naturalis and Capsicum frutescens are effective treatments for psoriasis. Green tea extract and tea tree oil have been investigated in the treatment of acne. Podophyllin and green tea extract are effective treatments for condylomata acuminata. Balm mint and a combination of sage and rhubarb have been shown to be effective in the treatment of herpes simplex in proof of concept studies.


Assuntos
Acne Vulgar/tratamento farmacológico , Condiloma Acuminado/tratamento farmacológico , Dermatite Atópica/tratamento farmacológico , Herpes Simples/tratamento farmacológico , Extratos Vegetais/uso terapêutico , Psoríase/tratamento farmacológico , Humanos , Resultado do Tratamento
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