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1.
Entropy (Basel) ; 24(12)2022 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-36554128

RESUMO

Several generalizations or extensions of the Boltzmann-Gibbs thermostatistics, based on non-standard entropies, have been the focus of considerable research activity in recent years. Among these, the power-law, non-additive entropies Sq≡k1-∑ipiqq-1(q∈R;S1=SBG≡-k∑ipilnpi) have harvested the largest number of successful applications. The specific structural features of the Sq thermostatistics, therefore, are worthy of close scrutiny. In the present work, we analyze one of these features, according to which the q-logarithm function lnqx≡x1-q-11-q(ln1x=lnx) associated with the Sq entropy is linked, via a duality relation, to the q-exponential function characterizing the maximum-entropy probability distributions. We enquire into which entropic functionals lead to this or similar structures, and investigate the corresponding duality relations.

2.
Entropy (Basel) ; 22(2)2020 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-33285938

RESUMO

Nonlinear Fokker-Planck equations (NLFPEs) constitute useful effective descriptions of some interacting many-body systems. Important instances of these nonlinear evolution equations are closely related to the thermostatistics based on the S q power-law entropic functionals. Most applications of the connection between the NLFPE and the S q entropies have focused on systems interacting through short-range forces. In the present contribution we re-visit the NLFPE approach to interacting systems in order to clarify the role played by the range of the interactions, and to explore the possibility of developing similar treatments for systems with long-range interactions, such as those corresponding to Newtonian gravitation. In particular, we consider a system of particles interacting via forces following the inverse square law and performing overdamped motion, that is described by a density obeying an integro-differential evolution equation that admits exact time-dependent solutions of the q-Gaussian form. These q-Gaussian solutions, which constitute a signature of S q -thermostatistics, evolve in a similar but not identical way to the solutions of an appropriate nonlinear, power-law Fokker-Planck equation.

3.
PLoS One ; 9(5): e96194, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24801682

RESUMO

We present a model for the electric potential profile across the membranes of neuronal cells. We considered the resting and action potential states, and analyzed the influence of fixed charges of the membrane on its electric potential, based on experimental values of membrane properties of the spinal ganglion neuron and the neuroblastoma cell. The spinal ganglion neuron represents a healthy neuron, and the neuroblastoma cell, which is tumorous, represents a pathological neuron. We numerically solved the non-linear Poisson-Boltzmann equation for the regions of the membrane model we have adopted, by considering the densities of charges dissolved in an electrolytic solution and fixed on both glycocalyx and cytoplasmic proteins. Our model predicts that there is a difference in the behavior of the electric potential profiles of the two types of cells, in response to changes in charge concentrations in the membrane. Our results also describe an insensitivity of the neuroblastoma cell membrane, as observed in some biological experiments. This electrical property may be responsible for the low pharmacological response of the neuroblastoma to certain chemotherapeutic treatments.


Assuntos
Potenciais de Ação , Potenciais da Membrana , Modelos Neurológicos , Neuroblastoma/fisiopatologia , Neurônios/fisiologia , Gânglios Espinais/citologia , Gânglios Espinais/fisiologia , Glicocálix/fisiologia , Humanos
4.
Chaos ; 19(1): 015116, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19335020

RESUMO

We review concepts introduced in earlier work, where a neural network mechanism describes some mental processes in neurotic pathology and psychoanalytic working-through, as associative memory functioning, according to the findings of Freud. We developed a complex network model, where modules corresponding to sensorial and symbolic memories interact, representing unconscious and conscious mental processes. The model illustrates Freud's idea that consciousness is related to symbolic and linguistic memory activity in the brain. We have introduced a generalization of the Boltzmann machine to model memory associativity. Model behavior is illustrated with simulations and some of its properties are analyzed with methods from statistical mechanics.


Assuntos
Encéfalo/fisiologia , Memória/fisiologia , Algoritmos , Teoria Freudiana , Humanos , Linguística , Transtornos Mentais/diagnóstico , Transtornos Mentais/fisiopatologia , Rememoração Mental/fisiologia , Modelos Neurológicos , Neurônios/metabolismo , Dinâmica não Linear , Probabilidade , Teoria Psicanalítica , Inconsciente Psicológico
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