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1.
Langenbecks Arch Surg ; 408(1): 202, 2023 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-37209306

RESUMO

PURPOSE: Postoperative wound complications are common in patients undergoing resection of lower extremity soft tissue tumors. Postoperative drainage therapy ensures adequate wound healing but may delay or complicate it. The aim of this study is to evaluate the incidence of postoperative wound complications and delayed or prolonged drainage treatment and to propose a standardized definition and severity grading of complex postoperative courses. METHODS: A monocentric retrospective analysis of 80 patients who had undergone primary resection of lower extremity soft tissue tumors was performed. A new classification was developed, which takes into account postoperative drainage characteristics and wound complications. Based on this classification, risk factors and the prognostic value of daily drainage volumes were evaluated. RESULTS: According to this new definition, regular postoperative course grade 0 (no wound complication and timely drainage removal) occurred in 26 patients (32.5%), grade A (minor wound complications or delayed drainage removal) in 12 (15.0%), grade B (major wound complication or prolonged drainage therapy) in 31 (38.8%), and grade C (reoperation) in 11 (13.7%) patients. Tumor-specific characteristics, such as tumor size (p = 0.0004), proximal tumor location (p = 0.0484), and tumor depth (p = 0.0138) were identified as risk factors for complex postoperative courses (grades B and C). Drainage volume on postoperative day 4 was a suitable predictor for complex courses (cutoff of 70 ml/d). CONCLUSION: The proposed definition incorporates wound complications and drainage management while also being clinically relevant and easy to apply. It may serve as a standardized endpoint for assessing the postoperative course after resection of lower extremity soft tissue tumors.


Assuntos
Sarcoma , Neoplasias de Tecidos Moles , Humanos , Estudos Retrospectivos , Radioterapia Adjuvante/efeitos adversos , Sarcoma/patologia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/terapia , Extremidade Inferior/cirurgia , Neoplasias de Tecidos Moles/cirurgia , Neoplasias de Tecidos Moles/patologia , Drenagem/efeitos adversos
2.
Childs Nerv Syst ; 7(7): 391-3, 1991 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-1794119

RESUMO

Transcranial Doppler sonography is a noninvasive method of obtaining information about changes in cerebral hemodynamics and intracranial pressure. After severe head injuries the development of brain swelling and brain edema can be assessed and the efficacy of treatment monitored. Development of severe brain edema accompanied by a rapid increase in intracranial pressure can be recognized by a decrease in blood flow velocity and rise in the pulsatility index. In hydrocephalic children the behavior of the cerebral blood flow velocity and the pulsatility index will warn of an increase of the ventricular fluid pressure or a shunt insufficiency.


Assuntos
Pressão do Líquido Cefalorraquidiano/fisiologia , Traumatismos Cranianos Fechados/diagnóstico por imagem , Hidrocefalia/diagnóstico por imagem , Monitorização Fisiológica , Adolescente , Velocidade do Fluxo Sanguíneo/fisiologia , Encéfalo/irrigação sanguínea , Edema Encefálico/diagnóstico por imagem , Edema Encefálico/fisiopatologia , Edema Encefálico/cirurgia , Derivações do Líquido Cefalorraquidiano , Criança , Pré-Escolar , Feminino , Traumatismos Cranianos Fechados/fisiopatologia , Traumatismos Cranianos Fechados/cirurgia , Humanos , Hidrocefalia/fisiopatologia , Hidrocefalia/cirurgia , Recém-Nascido , Doenças do Prematuro/diagnóstico por imagem , Doenças do Prematuro/fisiopatologia , Doenças do Prematuro/cirurgia , Masculino , Ultrassonografia
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