1.
Org Lett
; 23(14): 5378-5382, 2021 Jul 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34196560
RESUMO
We report a dual-catalytic platform for the cross-dehydrogenative-coupling between (benzo-)thiazoles and amines which combines low loadings of an iridium photoredox catalyst and a cobaloxime catalyst under blue light irradiation. This transformation occurs without stoichiometric oxidants, giving products in moderate to excellent yields. DFT calculations support the key role of Co(II) for rearomatization of the radical-addition intermediate to generate the product.