Psychological Dimensions Relevant to Motivation and Pleasure in Schizophrenia.

Motivation and pleasure deficits are common in schizophrenia, strongly linked with poorer functioning, and may reflect underlying alterations in brain functions governing reward processing and goal pursuit. While there is extensive research examining cognitive and reward mechanisms related to these deficits in schizophrenia, less attention has been paid to psychological characteristics that contribute to resilience against, or risk for, motivation and pleasure impairment. For example, psychological tendencies involving positive future expectancies (e.g., optimism) and effective affect management (e.g., reappraisal, mindfulness) are associated with aspects of reward anticipation and evaluation that optimally guide goal-directed behavior. Conversely, maladaptive thinking patterns (e.g., defeatist performance beliefs, asocial beliefs) and tendencies that amplify negative cognitions (e.g., rumination), may divert cognitive resources away from goal pursuit or reduce willingness to exert effort. Additionally, aspects of sociality, including the propensity to experience social connection as positive reinforcement may be particularly relevant for pursuing social goals. In the current review, we discuss the roles of several psychological characteristics with respect to motivation and pleasure in schizophrenia. We argue that individual variation in these psychological dimensions is relevant to the study of motivation and reward processing in schizophrenia, including interactions between these psychological dimensions and more well-characterized cognitive and reward processing contributors to motivation. We close by emphasizing the value of considering a broad set of modulating factors when studying motivation and pleasure functions in schizophrenia.

What gets in the way of social engagement in schizophrenia?

BACKGROUND: Social engagement-important for health and well-being-can be difficult for people with schizophrenia. Past research indicates that despite expressing interest in social interactions, people with schizophrenia report spending less time with others and feeling lonely. Social motivations and barriers may play an important role for understanding social engagement in schizophrenia. AIM: To investigate how people with schizophrenia describe factors that impede and promote social engagement. METHODS: We interviewed a community sample of people with (n = 35) and without (n = 27) schizophrenia or schizoaffective disorder about their social interactions with friends and family over the past week and planned social activities for the coming week. We reviewed the interview transcripts and developed a novel coding system to capture whether interactions occurred, who had initiated the contact, and frequency of reported social barriers (i.e., internal, conflict-based, logistical) and social motivations (i.e., instrumental, affiliative, obligation-based). We also assessed symptoms and functioning. RESULTS: People with schizophrenia were less likely than people without schizophrenia to have spent time with friends [t (51.04) = 2.09, P = 0.042, d = 0.51)], but not family. People with schizophrenia reported more social barriers than people without schizophrenia [F (1, 60) = 10.55, P = 0.002, ηp2 = 0.15)] but did not differ in reported social motivations. Specifically, people with schizophrenia reported more internal [t (45.75) = 3.40, P = 0.001, d = 0.83)] and conflict-based [t (40.11) = 3.03, P = 0.004, d = 0.73)] barriers than people without schizophrenia. Social barriers and motivations were related to real-world social functioning for people with schizophrenia, such that more barriers were associated with more difficulty in close relationships (r = -0.37, P = 0.027) and more motivations were associated with better community functioning (r = 0.38, P = 0.024). CONCLUSION: These findings highlight the importance of assessing first person accounts of social barriers and motivations to better understand social engagement in schizophrenia.

Context Effects on Facial Affect Recognition in Schizophrenia and Autism: Behavioral and Eye-Tracking Evidence.

Although Schizophrenia (SCZ) and Autism Spectrum Disorder (ASD) share impairments in emotion recognition, the mechanisms underlying these impairments may differ. The current study used the novel "Emotions in Context" task to examine how the interpretation and visual inspection of facial affect is modulated by congruent and incongruent emotional contexts in SCZ and ASD. Both adults with SCZ (n= 44) and those with ASD (n= 21) exhibited reduced affect recognition relative to typically-developing (TD) controls (n= 39) when faces were integrated within broader emotional scenes but not when they were presented in isolation, underscoring the importance of using stimuli that better approximate real-world contexts. Additionally, viewing faces within congruent emotional scenes improved accuracy and visual attention to the face for controls more so than the clinical groups, suggesting that individuals with SCZ and ASD may not benefit from the presence of complementary emotional information as readily as controls. Despite these similarities, important distinctions between SCZ and ASD were found. In every condition, IQ was related to emotion-recognition accuracy for the SCZ group but not for the ASD or TD groups. Further, only the ASD group failed to increase their visual attention to faces in incongruent emotional scenes, suggesting a lower reliance on facial information within ambiguous emotional contexts relative to congruent ones. Collectively, these findings highlight both shared and distinct social cognitive processes in SCZ and ASD that may contribute to their characteristic social disabilities.