RESUMO
A hospital outbreak, traced to a case of Norwegian scabies, resulted in 45 and 32 symptomatic cases in staff and patients, respectively. A total of 228 asymptomatic in-patient contacts and over 500 staff required prophylactic treatment with either 1% gamma benzene hexachloride lotion or 5% permethrin cream. Recurrences occurred in seven staff members and five patients. The outbreak was contained within four months.
Assuntos
Infecção Hospitalar/prevenção & controle , Surtos de Doenças , Controle de Infecções/métodos , Doenças Profissionais/prevenção & controle , Escabiose/prevenção & controle , Idoso , Idoso de 80 Anos ou mais , Infecção Hospitalar/epidemiologia , Infecção Hospitalar/transmissão , Feminino , Humanos , Doenças Profissionais/epidemiologia , Recursos Humanos em Hospital , Escabiose/epidemiologia , Escabiose/transmissãoRESUMO
Clinical experience with five patients exposed to phosgene is described. The treatment of phosgene poisoning was focused upon the presenting problem, pulmonary edema. Arterial hypoxemia was treated with a face mask with 10 cm CPAP with the FiO2 adjusted as needed or with a volume ventilator with controlled ventilation. Ventilation was controlled to reduce the work of breathing. Metabolic acidosis was treated with NaCHO3 to produce a normal pH. A vigorous program of diuresis was used to treat the pulmonary edema. Lasix was administered to produce a negative fluid balance while maintaining a good urinary output. The negative fluid balance correlated well with reduced oxygen requirements.
Assuntos
Fosgênio/intoxicação , Edema Pulmonar/induzido quimicamente , Desequilíbrio Ácido-Base/tratamento farmacológico , Desequilíbrio Ácido-Base/etiologia , Adulto , Bicarbonatos/uso terapêutico , Terapia Combinada , Furosemida/uso terapêutico , Humanos , Hipóxia/etiologia , Hipóxia/terapia , Edema Laríngeo/induzido quimicamente , Masculino , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/terapia , Oxigenoterapia , Edema Pulmonar/complicações , Edema Pulmonar/terapia , Sódio/uso terapêutico , Bicarbonato de SódioRESUMO
An infectious bronchitis virus, designated G48, isolated from birds during an outbreak of nephritis in a previously vaccinated broiler flock, overcame the resistance induced in birds vaccinated with 2 commercially available vaccines. Birds vaccinated with the A isolate of infectious bronchitis resisted challenge with this new virus. Cross neutralisation studies revealed that the new virus was serologically distinct from the 4 viruses tested. Homologous antiserum to G48 did not neutralise the other viruses and only antiserum to the A virus completely neutralised the new virus.
