Long-Term Exposure to Ambient Hydrocarbons Increases Dementia Risk in People Aged 50 Years and above in Taiwan.

BACKGROUND: Alzheimer's disease, the most common cause of dementia among the elderly, is a progressive and irreversible neurodegenerative disease. Exposure to air pollutants is known to have adverse effects on human health, however, little is known about hydrocarbons in the air that can trigger a dementia event. OBJECTIVE: We aimed to investigate whether long-term exposure to airborne hydrocarbons increases the risk of developing dementia. METHOD: The present cohort study included 178,085 people aged 50 years and older in Taiwan. Cox proportional hazards regression analysis was used to fit the multiple pollutant models for two targeted pollutants, including total hydrocarbons and non-methane hydrocarbons, and estimated the risk of dementia. RESULTS: Before controlling for multiple pollutants, hazard ratios with 95% confidence intervals for the overall population were 7.63 (7.28-7.99, p <0.001) at a 0.51-ppm increases in total hydrocarbons, and 2.94 (2.82-3.05, p <0.001) at a 0.32-ppm increases in non-methane hydrocarbons. The highest adjusted hazard ratios for different multiple-pollutant models of each targeted pollutant were statistically significant (p <0.001) for all patients: 11.52 (10.86-12.24) for total hydrocarbons and 9.73 (9.18-10.32) for non-methane hydrocarbons. CONCLUSION: Our findings suggest that total hydrocarbons and non-methane hydrocarbons may be contributing to dementia development.

Workplace smoking policies in Taiwan and their association with employees' smoking behaviours.

BACKGROUND: The implementation of worksite smoking policies has shown significant effects on reducing employees' smoking consumption and protecting non-smoking workers. However, there are no data about workplace smoking policies in Taiwan. The purpose of this study was to document the status of worksite smoking policies in Taiwan and its potential impact on employees' smoking behaviours. METHODS: A two-stage investigation was conducted. The first stage was to examine the current status of workplace smoking policies and the second was to evaluate the relationship between workplace smoking policies and employees' smoking behaviours. After two follow-ups in each stage, 264 companies and 1141 employees returned their questionnaires. RESULTS: Workplace smoking policies were associated with types of businesses and size of workplaces. Only approximately half of manufacturing and service companies have implemented a prohibitive smoking policy. Large facilities (>750 employees) were more likely to implement a prohibitive policy (57%). Employees in workplaces with a prohibitive policy had lower prevalence of smoking and cigarette consumption, and less exposure to passive smoking. Although most smokers agreed with banning smoking in their work environment, no difference in interest in participating in cessation programs was found. CONCLUSIONS: Significant associations were found between workplace smoking policies and employees' smoking behaviours. Results of the study provide basic information for designing more refined smoking policies in the workplace in Taiwan.

Controlling cigarette smoking in the workplace in Taiwan: opportunities and challenges.

Cigarette smoking is one of the most serious health problems in Taiwan. Although the Taiwanese government passed a Tobacco Hazard Control Act in 1997, it is not fully applicable to the workplace. The purpose of the study was to review workplace smoking prevalence and policies, and to discuss the opportunities and challenges of implementing workplace smoking policies in Taiwan. Results show that smoking prevalence in the workplace in Taiwan is high, particularly among males, ranging from 38 to 68%. More than 75% of smokers in Taiwan smoke in the workplace. The percentage of workplaces implementing restrictive smoking policies in Taiwan is low, particularly in small-sized workplaces. The Tobacco Hazard Control Act in Taiwan has not been strongly enforced in public places, let alone in private companies. Several constructive suggestions are presented in the study. For example, establishing workplace smoking policies, informing employers that second-hand smoke is a human carcinogen, providing financial support for employers to initiate cessation programs, and modifying the current Tobacco Hazard Control Act, etc.