Treatment outcomes of hips in patients with epiphyseal dysplasia.

Hip containment surgeries in multiple epiphyseal and spondyloepiphyseal dysplasia (MED/SED) patients aim to improve the mechanical environment of the hip joint. The purpose of this study was to determine if surgical intervention to improve femoral head coverage improved radiographic and clinical outcomes. A retrospective study identified patients with MED/SED seen in clinic between May 2000 and September 2017, with a minimum of 2-year follow-up. Patient charts/radiographs were reviewed for radiographic hip measurements, pain, and gait. Sixty-nine hips in 35 patients were identified. Forty-four hips were treated nonoperatively and 25 were treated surgically. The mean age at diagnosis was 6.2 years. The mean follow-up was 7.7 years for the surgical group and 7.1 years for the nonsurgical group. The mean postoperative follow-up was 5.4 years. Acetabular index decreased from initial to final visit by 9.0° in the surgical group and 1.6° in the nonsurgical group. Tonnis angle decreased by 13.5° in the surgical group and 1.5° in the nonsurgical group. Center edge angle increased by 19.0° in the surgical group and 7.1° in the nonsurgical group. Hips in the surgical group were 6.1 times more likely to experience an improvement in pain compared with hips in the nonsurgical group. Gait at the final follow-up was similar among the two groups. In this study cohort, containment surgery provided increased femoral head coverage; however, there was equal femoral head deformation despite intervention. Hips treated surgically were more likely to experience an improvement in pain; however, gait alterations did not improve.

Treatment of Hip Instability in Children With Down Syndrome: Keys to Managing a Challenging Problem.

INTRODUCTION: Management of hip instability in children with Down syndrome is a challenging task to undertake for even the most experienced surgeons. As life expectancy of these patients increases, the importance of preserving functional mobility and hip joint stability in order to minimize late hip degeneration and pain has become a priority. The aim of this study is to evaluate the clinical and radiographic outcomes of children with Down syndrome and hip instability who underwent surgical reconstruction with femoral and/or acetabular procedures. METHODS: We performed a retrospective review of all children with Down syndrome age 18 years and younger, who underwent surgical intervention to address hip instability between 2003 and 2017. Data was recorded detailing the patient's demographics, preoperative and postoperative functional status and surgical details. Preoperative and postoperative radiographic analysis was performed as well as 3-dimensional computed tomography scan evaluation, when available. All major and minor complications were recorded and classified using the Severin radiographic classification and the Clavien-Dindo-Sink clinical classification. RESULTS: We studied 28 hips in 19 children that were followed for an average of 4.4 years postsurgical intervention for hip instability. The majority of patients improved in all radiographic parameters. A total of 14 hips (50%) had complications and 9 hips (32%) required a secondary surgery. Of those complications, 2 hips (7%) developed avascular necrosis and 4 hips (14%) developed recurrent instability after the index procedure. Two of these hips had a subsequent anteverting periacetabular osteotomy that produced a stable hip at final follow up. DISCUSSION: Surgical management of hip instability in children with Down syndrome remains challenging. The treating surgeon must have a thorough understanding of the pathoanatomy and design the surgical treatment to meet all of the underlying sources of instability. Combined femoral and acetabular osteotomies plus capsulorrhaphy are often required along with postoperative hip spica immobilization. Although complication and revision surgery rates are high, hip stability and good functional outcomes can be achieved.

Ligamentum Teres Transfer During Medial Open Reduction in Patients with Developmental Dysplasia of the Hip.

BACKGROUND: The ligamentum teres (LT) is believed to have a number of functions, including a role in hip stability, nociception, proprioception, vascular supply to the femoral head, and synovial fluid circulation. The LT is often excised in the process of performing a medial open reduction (MOR) of the hip. We sought to conduct a retrospective review of hips undergoing a MOR for dislocated infantile developmental dysplasia of the hip (DDH) to compare clinical and radiographic outcomes for patients with and without LT reconstruction. METHODS: We performed a retrospective review of 38 hips treated with MOR with or without LT reconstruction with minimum two-year follow-up. Radiographic outcomes were determined using the Severin score. Information regarding avascular necrosis (AVN), concomitant surgical procedures, repeat dislocation, subsequent surgery, limp, pain, and range of motion symmetry was recorded. RESULTS: Eighteen hips that underwent MOR with LT reconstruction were compared to 20 hips that underwent MOR without LT reconstruction. Mean follow up for this cohort was 70.1 months (median: 61.8; Range: 24.2 to 182.2 months). The group with LT reconstruction had an 11% rate of AVN, the group without LT reconstruction had a 15% rate of AVN (p=1.0) No hips in either group re-dislocated or had pain at final follow up. Two hips (5%) had a limp at most recent follow up, all were in the group that did not receive a LT reconstruction (p=0.488). Three hips (17%) in the LT reconstruction group and one hip (5%) in the other group had asymmetrical hip range of motion at final follow up (p=0.328). CONCLUSION: This study offers preliminary data to suggest that ligamentum teres reconstruction is a safe procedure that can minimize the risk for subluxation or re-dislocation that can occur within the post reduction hip spica cast. Although in this study, the patients who did not have LT reconstruction had a similar re-dislocation rate, we believe that ligamentum teres preservation is a useful adjunct to medial open reduction, especially in centers that may only treat occasional cases or have less experience in applying an excellent hip spica cast.Level of Evidence: III.

Classifying Ischial Tuberosity Avulsion Fractures by Ossification Stage and Tendon Attachment.

BACKGROUND: We propose a new classification system for ischial tuberosity fractures in adolescents that is based on the ossification pattern of the apophysis. METHODS: We performed a retrospective review of patients who were diagnosed with ischial tuberosity avulsion fractures at a single institution from 2008 to 2018. Skeletal maturity and fracture location, size, and displacement were recorded based on initial injury radiographs. The fractures were classified by location as being lateral (type 1) or complete (type 2). Pelvic computed tomography (CT) review demonstrated 5 stages of ossification. We then reviewed pelvic CT and magnetic resonance imaging scans to assess the tendinous insertions at the ischial tuberosity apophysis. Reliability analysis was performed. RESULTS: We identified 45 ischial tuberosity fractures. The mean patient age was 14.4 years (range, 10.3 to 18.0 years). Boys accounted for 82% of the cohort. Forty-seven percent of the fractures were classified as type 1, and 53% were classified as type 2. Type-1 fractures were associated with younger age (p = 0.001), lower Risser score (p = 0.002), lower modified Oxford score (p = 0.002), less displacement (p = 0.001), and smaller size (p < 0.001) when compared with type-2 fractures. Of the 45 patients, 18 had follow-up of >6 months, with 56% going on to nonunion. Nonunion was associated with greater displacement (p = 0.016) and size (p = 0.027). When comparing union rates by fracture type, 33% of type-1 fractures progressed to nonunion, while 78% percent of type-2 fractures progressed to nonunion; however, this difference was not significant (p = 0.153). A review of the advanced imaging indicated that type-1 fractures involved the semimembranosus and conjoined tendons, whereas type-2 fractures also involved the adductor magnus tendon. CONCLUSIONS: We propose a new classification system based on the ossification pattern of the ischial tuberosity apophysis that reflects the skeletal maturity of the patient, the size and location of the fracture, and the amount of displacement, and likely predicts the probability of subsequent nonunion. The ischial tuberosity ossifies in a pattern similar to the iliac crest as described by Risser, and this pattern of ossification dictates the size of the ischial tuberosity avulsion fracture fragments and the involved tendons.

Historical Aspects of DDH.

BACKGROUND: Little was known about developmental dysplasia of the hip (DDH) in the early historical era. Symptoms such as limping were caused by a variety of disease processes, many of which were life threatening. It was not until the discovery of X-ray in 1896 that clear understanding of childhood hip conditions, including DDH, could evolve. METHODS: We reviewed available literature and distilled it into this summary of the history of our understanding of DDH. RESULTS: The development of non-operative methods relied on plaster of Paris cast reductions and later splints and harness systems leading to the Pavlik harness (1950's). The development of ultrasound as a diagnostic technique made early diagnosis and treatment possible. Surgical approaches to DDH treatment required several key discoveries: invention of general anesthesia (1840s); development of sterilization techniques (1860-1880); discovery of X-ray (1890s); development of stainless steel (1920s); and the discovery of antibiotics (1930s). These surgical advances allowed the development of a remarkable variety of operations to treat DDH including open reduction techniques, and osteotomies of the acetabulum and proximal femur. CONCLUSION: The path to accurate diagnosis and predictable treatment of DDH parallels the many advances that application of the scientific method has allowed in the specialty of orthopedic surgery. The development of academic centers that focus on research and education in childhood hip disorders, as well as a growing number of centers that focus on hip problems in adolescents and young adults, assure a continuous and changing "history" of this common childhood hip condition.

Comparison of Surgical Outcomes Between a Triplane Proximal Femoral Osteotomy and the Modified Dunn Procedure for Stable, Moderate to Severe Slipped Capital Femoral Epiphysis.

BACKGROUND: Recent studies have demonstrated the intra-articular cartilage and labral damage that can occur from the proximal femoral cam-like deformity of a moderate to severe slipped capital femoral epiphysis (SCFE). The approach to treating this deformity in a symptomatic Loder stable hip is controversial. The purpose of this study was to compare radiographic outcomes, complication rates, and revision rates between Imhauser type triplane proximal femoral osteotomy (TPFO) and the modified Dunn procedure (MDP). METHODS: Twenty-six subjects with minimum 1-year follow-up were included (12 treated with a TPFO, and 14 treated with the MDP). A chart review was performed to capture data related to complications, revision procedures, surgical time, and body mass index. Radiographs were measured preoperatively and at final follow-up to evaluate epiphyseal-slip angle, neck-shaft angle, articular surface to trochanter distance, and medial proximal femoral angle. RESULTS: Surgical time was shorter for the TPFO group (150.0±57.4 min) compared with the MDP group (203.8±30 min) (P=0.005). All preoperative and postoperative radiographic measures were similar between the 2 groups except postoperative neck-shaft angle, which was significantly less in the TPFO group (129.7±8.6 vs. 140.9±9.4 degrees) (P=0.005). There were no cases of femoral head avascular necrosis (AVN) in the TPFO group. The modified Dunn group had a 29% AVN rate (P=0.1). The overall complication rate was similar between the TPFO (33%) and modified Dunn (36%) groups (P=1.0) and the reoperation rate was slightly greater in the TPFO group (33%) as compared with the modified Dunn group (21%) (P=0.67). CONCLUSIONS: The complex 3-dimensional proximal femoral deformity of a moderate to severe SCFE can be difficult to treat with relatively high complication/reoperation rates observed in both TPFO and MDP groups. All 4 instances of AVN in this study of stable slips, however, were in the MDP group. As this can be a devastating complication leading to early total hip arthroplasty, we advise against the MDP in stable SCFE patients. LEVEL OF EVIDENCE: Level III-retrospective comparative study.

Analysis of Acetabular Ossification From the Triradiate Cartilage and Secondary Centers.

BACKGROUND: Acetabular development is a complex process that involves both endochondral growth from the triradiate cartilage (TRC) and intramembranous growth from the primary and secondary ossification centers of the innominate bones. Ponseti and others have described these centers including their contribution toward the development of normal acetabular shape. Prior studies have not utilized advanced imaging to study the appearance and closure of these secondary centers. The purpose of this study was to determine the chronological age at which the secondary ossification centers of the acetabulum appear and close and where there are any sex differences. METHODS: Patients who underwent abdominal and pelvic computed tomography (CT) scans between January 2009 and December 2014 at a pediatric hospital were retrospectively reviewed. Patients between age 6 and 16 years with adequate imaging of acetabulum were included. CT scans were assessed for the appearance and closure of the 3 acetabular secondary ossification centers [anterior (os pubis), superior (os ilium), and posterior (os ischium)] and closure of the TRC. RESULTS: A total of 159 CT scans met inclusion criteria (66 males and 93 females). The median age of appearance of the secondary ossification centers was: posterior (10.1 females, 12.8 males), anterior (10.7 females, 13.4 males), and superior (11.1 females, 13.6 males). The median age of closure of the secondary ossification centers was: posterior (12.8 females, 13.6 males), anterior (12.8 females, 13.9 males), superior (14.5 females, 13.9 males), and TRC (14.5 females, 14.3 males). Most ossification centers in females appeared and closed approximately 2 to 3 years before males. CONCLUSIONS: Secondary ossification centers in the acetabulum appear sequentially (first posterior, then anterior, then superior), with almost all centers closing just before TRC. Closure occurs earlier in females than males. Knowledge of these centers and their closure patterns allows better radiologic readings (especially CT studies) and understanding of acetabular growth, allowing more informed management of childhood hip conditions including dysplasia, trauma, and over-use sports injuries. LEVEL OF EVIDENCE: Level III-Diagnostic.

Femoral version: Comparison among advanced imaging methods.

Accurate assessment of femoral version is essential to the surgical treatment of lower extremity deformities, yet the ideal modality and technique to measure femoral version is controversial. This study explored two hypotheses: First, there is no difference in the accuracy of femoral version measurement from 2D CT, 2D MRI, and 3D biplanar radiography reconstructions compared to a 3D model created from CT. Second, there is a difference between the measured version from traditional axial sections of the proximal femur compared to femoral neck oblique sections for CT and MRI. Eight adult cadaver lower extremities underwent CT, MRI, and biplanar radiography. Femoral version measurements from the CT and MRI axial and oblique sections, as well as biplanar radiography reconstructions, were compared to 3D reconstructed models from CT. All five techniques underestimated femoral version compared to the 3D model, but none were statistically significantly different. Regarding the first hypothesis, all five techniques had excellent correlation (r > 0.81, p ≤ 0.01) with the 3D model. Concerning the second hypothesis, the CT and MRI version measurements in femoral neck oblique sections were greater by 5.4° and 1.4°compared to traditional axial sections, respectively. All five techniques across three modalities provided accurate assessment of femoral version, suggesting that the treating physician's choice of modality can be determined per individual patient, not on measurement accuracy. CLINICAL SIGNIFICANCE: In choosing a modality to determine femoral version, consider the advantages and disadvantages of each modality for the individual patient, using femoral neck oblique slices for CT and MRI when available. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1536-1542, 2018.

Electronic Medical Record Adoption: The Effect on Efficiency, Completeness, and Accuracy in an Academic Orthopaedic Practice.

INTRODUCTION: The electronic medical record (EMR) is the new platform for documenting health information. The purpose of this study is to evaluate the impact of the EMR on efficiency, completeness, accuracy, and surgeon attitude in the orthopaedic program of a training hospital. METHODS: Sixty paper charts were compared with 60 EMRs. Pre-EMR and post-EMR billing data was used to determine outpatient clinic volume and the number of providers seeing patients per month. Completeness was evaluated by noting the presence of items from a predetermined list of clinical information pertinent to each diagnosis. Age and side of injury was used to evaluate note accuracy. A survey was used to evaluate surgeon's attitudes regarding the EMR. RESULTS: There was no difference in monthly volume pre-EMR and post-EMR. There was an increase in the number of providers needed to see patients, equating to a 19% reduction in the number of patient visits per provider. The EMR was 1.3 times more likely to include pertinent clinical information. Both paper charts and the EMR were highly accurate. The surgeon attitude survey revealed concerns regarding clinic efficiency, increased "off-hours" record keeping, and decreased clinic teaching. DISCUSSION: EMR is an important and essential component of medical care delivery. Record completion and accuracy were similar across medical record types. The use of EMR led to a 19% reduction in patients per provider. Creating the record in the clinic setting appears to detract from patient interaction, and resident/fellow education time. A more focused, specialty designed, EMR may be more efficient for an orthopaedic practice. Future EMR technology should allow a focused EMR designed for specialties that is efficient to create but that can be electronically converted into a "master record" that meets the needs of an associated larger organization. LEVEL OF EVIDENCE: Level III-retrospective comparative study.

Advanced Containment With Triple Innominate Osteotomy in Legg-Calve-Perthes Disease: A Viable Option Even in Severe Cases.

BACKGROUND: Legg-Calve-Perthes disease (LCPD), in its severe form, remains a challenge. More recent classifications, particularly the modified Elizabethtown classification, have highlighted the chronologic stage of LCPD and its effect on surgical outcome. Hip severity and age of disease onset have also been shown to be powerful determinants of outcome. This study was performed to determine whether disease stage, disease severity, or patient age, are absolute indicators of whether a patient can benefit from surgical containment with triple innominate osteotomy (TIO). METHODS: All patients with LCPD treated with TIO between 1995 and 2011 were collected. Only those patients with a minimum of 2-year radiographic follow-up and no previous or concomitant femoral realignment surgery were included. Fifty-four patients (56 hips) met our inclusion criteria. The modified Elizabethtown classification was used to classify disease stage as early (

Analysis of spinal alignment and pelvic parameters on upright radiographs: implications for acetabular development.

UNLABELLED: The purpose of this study was to correlate measures of sagittal spinopelvic alignment [lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT) and pelvic incidence (PI)] and measures of acetabular coverage [lateral center edge angle (LCEA) and Tonnis angle] in asymptomatic adolescents on standing biplanar radiographs. We hypothesized that subjects with increased pelvic incidence and LL would have increased anterior PT and increased measures of acetabular coverage. Upright anteroposterior and lateral spinopelvic radiographs were obtained using EOS imaging technique. LCEA and Tonnis angle were calculated on the anteroposterior images and the lateral images were analyzed for LL, PI, PT and SS. LL was found to have a strong correlation with SS (r s = 0.786, P < 0.001), moderate correlation with PI (r s = 0.529, P < 0.001), and a poor inverse correlation with PT (r s = -0.167, P = 0.018). However, LCEA was not found to be significantly correlated with PT (r s = 0.084, P = 0.238) and Tonnis angle was not found to be correlated with any of the sagittal spinopelvic measures. Healthy, asymptomatic adolescents with increased pelvic incidence and lumbar lordosis did not have increased anterior PT or increased measures of acetabular coverage. The correlations identified in previous cadaveric studies or clinical studies evaluating changes between supine and standing radiographs are not supported in this healthy adolescent population. Our findings may suggest that an individual's acetabulum develops as a dynamic adaptation to one's particular sagittal spinopelvic alignment to optimize femoral head coverage. LEVEL III: Diagnostic - Investigating a diagnostic test.

Defining the lateral edge of the femoroacetabular articulation: correlation analysis between radiographs and computed tomography.

PURPOSE: The purpose of this study was to analyze the variation in measuring the lateral center edge angle of Wiberg (LCEA) using the lateral edge of the sourcil (LCEA-S) compared to the lateral edge of the acetabulum (LCEA-E), and to correlate these measurements with three-dimensional computed tomography (3D-CT)-based analysis of the femoroacetabular articulation. METHODS: A retrospective analysis was performed on 24 patients (45 hips) treated for hip dysplasia at a single institution. All patients were required to have an anteroposterior (AP) pelvis radiograph and pelvic CT. LCEA-S and LCEA-E measurements were calculated from radiographs. Axial CT images were processed to standardize pelvic orientation and calculate the LCEA at three points (posterior, central, anterior) along the acetabular edge. Correlation analysis was used to evaluate radiographic and CT measures. RESULTS: Eight males and 16 females with an average age of 14.6 years were included. The LCEA-S (16.5° ± 2.0°) was found to be significantly less than the LCEA-E (26.0° ± 2.0°) (p < 0.001). The LCEA-S had the greatest correlation with the central measurement on the 3D-CT (r s = 0.893; p < 0.001). The LCEA-E had the greatest correlation with the anterior measurement on the 3D-CT (r = 0.834; p < 0.001). CONCLUSIONS: The LCEA can change significantly depending on the bony landmark used to define the lateral edge of the femoroacetabular articulation. The edge of the sourcil most closely correlates with the central weight-bearing portion of the articular surface on the 3D-CT and should be used to define the LCEA when treating patients with hip dysplasia. LEVEL OF EVIDENCE: Level III, retrospective comparison study.

Sex Differences in Cartilage Topography and Orientation of the Developing Acetabulum: Implications for Hip Preservation Surgery.

BACKGROUND: Increased attention is being placed on hip preservation surgery in the early adolescent. An understanding of three-dimensional (3-D) acetabular development as children approach maturity is essential. Changes in acetabular orientation and cartilage topography have not previously been quantified as the adolescent acetabulum completes development. QUESTIONS/PURPOSES: We used a novel 3-D CT analysis of acetabular development in children and adolescents to determine (1) if there were sex-specific differences in the growth rate or surface area of the acetabular articular cartilage; (2) if there were sex-specific differences in acetabular version or tilt; and (3) whether the amount of version and tilt present correlated with acetabular coverage. METHODS: We assessed acetabular morphology in 157 patients (314 hips); 71 patients were male and 86 were female. Patient ages ranged from 8 years to 17 years. A 3-D surface reconstruction of each pelvis was created from CT data using MIMICs software. Custom MATLAB software was used to obtain data from the 3-D reconstructions. We calculated articular surface area, acetabular version, and acetabular tilt as well as novel measurements of acetabular morphology, which we termed "coverage angles." These were measured in a radial fashion in all regions of the acetabulum. Data were organized into three age groups: 8 to 10 years old, 10 to 13 years old, and 13 to 17 years old. RESULTS: Male patients had less acetabular anteversion in all three age groups, including at maturity (7° versus 13°, p<0.001; 10° versus 17°, p<0.001; 14° versus 20°, p<0.001). Males had less acetabular tilt in all three age groups (32° versus 34°, p=0.03; 34° versus 38°, p<0.001; 39° versus 41°, p=0.023). Increases in anteversion correlated with increased posterior coverage angles (r=0.805; p<0.001). Increases in tilt were correlated with increases in superior coverage angles (r=0.797; p<0.001). The posterosuperior regions of the acetabulum were the last to develop and this process occurred earlier in females compared with males. Articular surface area increased from 18 (8-10 years) to 24 cm(2) (13-17 years) in males and from 17 (8-10 years) to 21 cm(2) (13-17 years) in females. [corrected]. Articular surface area was higher in males beginning in the 10- to 13-year-old age group (p=0.001). CONCLUSIONS: Using a novel technique to analyze acetabular morphology, we found that acetabular development occurs earlier in females than males. The posterosuperior region of the acetabulum is the final region to develop. The articular cartilage surface area and articular cartilage coverage of the femoral head are increasing in addition to total coverage of the femoral head during the final stages of acetabular development. LEVEL OF EVIDENCE: Level III, prognostic study.

Acute, unstable, slipped capital femoral epiphysis: is there a role for in situ fixation?

BACKGROUND: Slipped capital femoral epiphysis, a common disorder in adolescents, may be increasing in incidence in North America because of the obesity epidemic. In most cases, the slip is mild and can be treated with in situ fixation. Even in more severe cases of a stable slip, in situ fixation remains a widely accepted choice. When the slip is acute and unstable, treatment remains controversial. We reviewed the orthopaedic literature and our personal experience in managing acute, unstable slipped capital femoral epiphysis. The reported range of avascular necrosis (AVN) is high and the literature shows no clear recommendations for the best treatment choice. Treatment choices include: in situ stabilization with possible later corrective osteotomy, formal manipulative closed reduction plus screw fixation, partial reduction through an open approach with the hip joint decompressed (Parsch method), and anatomic reduction by the modified Dunn method. Review of the literature and our experience suggests a high AVN rate in acute unstable slips no matter what treatment method is selected. Most North American reports suggest an AVN rate with in situ screw fixation ranging from 20% to 50%. The method described by Parsch, which includes an urgent, open capsulotomy, joint decompression, and gentle partial reduction, shows a low AVN rate as reported from his institution (<10%). The AVN rate reported for anatomic reduction (modified Dunn procedure) performed through an open surgical hip dislocation was initially quite low, but after being restudied in North American centers appears to be about 25%. CONCLUSIONS: Safe treatment of an acute unstable slip remains problematic. The literature suggests that these patients should be treated urgently; however, simple in situ stabilization results in a high AVN rate. A likely safer modification is to open the hip anteriorly to decompress the joint and to stabilize after partial reduction as described by Parsch. The modified Dunn method is becoming more widely used, but results in North American centers cite a significant AVN rate.

Fundamental concepts of developmental dysplasia of the hip.

To provide the best possible care to patients with developmental dysplasia of the hip, it is helpful to understand the normal growth and development of the hip joint; the pathoanatomy, epidemiology, and diagnosis of the condition; and the natural history of a missed diagnosis of dislocation, subluxation, and dysplasia.