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Objective:To compare the pregnancy outcome and neonates prognosis in the late pregnant women with or without group B streptococcus (GBS) infection, and the women with or without standard treatment for GBS, so as to provide scientific evidence for improving the maternal and infant prognosis.Methods:From July 2018 to June 2019, women in the late stage of pregnancy who came to Tongzhou Maternal & Child Health Hospital of Beijing for prenatal examination were selected in our study. Questionnaire survey and GBS sampling test were conducted. They were divided into two groups based on the result of GBS positive or negative, and women with GBS infection were further divided two groups whether they accepted standard treatment for GBS or not. All of them were followed up to observe and record the situation of pregnancy outcome and neonates prognosis.Results:1 127 women completed the GBS test and follow-up in this study with an average age of (26.5±4.8)years old and a mean gestation of (36.6±0.9)weeks. Of them, 142 women were tested for GBS positive, and the rate of GBS infection was 12.6%. 104 women (73.2%) accepted the standard treatment for GBS. The incidence of puerperium infection (4.9% vs 0.9%, P=0.001), neonatal infection (2.1% vs 0.1%, P=0.003), neonatal asphyxia (2.8% vs 0.5%, P=0.017), amniotic fluid pollution (4.2% vs 1.1%, P=0.013) in the GBS positive group were significantly higher than those of the GBS negative group. Furthermore, the incidence of puerperium infection (13.2% vs 1.9%, P=0.021) and amniotic fluid pollution (15.8% vs 0, P<0.001) in the group with out GBS standard treatment were significantly higher than the group with GBS standard treatment. Conclusions:GBS infection in the late stage of pregnancy can significantly increase the incidence of infection, and the outcome for pregnant women and infant may be worse if they do not accept standard treatment. Therefore, GBS screening for pregnant women in the late stage of pregnancy and early effective treatment are very essential to improve the maternal and infant prognosis.
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Objective To investigate the epidemic characteristics of pregnancy hypothyroidism combined with preeclampsia (PE) in Tongzhou District of Beijing from 2015 to 2019, analyze the influencing factors, and provide a reference for the development of scientific prevention and control measures. Methods A descriptive epidemiological method was used to analyze the data. The incidence rate of pregnancy hypothyroidism combined with PE and related epidemiological survey data from 2015 to 2019 in Tongzhou District of Beijing were analyzed. Logistic regression equation was established to analyze its related factors. SPSS 20 was used for t test, rank sum test and Spearman rank correlation test with a test significance level of 0.05. Results In 2015-2019, there were 267 pregnant women with PE in Luhe hospital, maternal and child health care hospital, Tongzhou District second hospital, Tongzhou District Third Hospital, No.263 Hospital of PLA and Zhang Jia Wan hospital in Tongzhou District of Beijing. The average annual incidence rate of hypothyroidism combined with PE in pregnant women was 0.07% (267/5/77 015), and varied each year. A questionnaire survey was conducted on the 267 cases by the investigation team. A total of 262 valid data sheets were recovered after removing residual pages, repeated samples and unqualified questionnaires. The incidence of hypothyroidism combined with PE was higher in women aged ≤ 20 years and 35-45 years, in rural areas, and with an education level below high school, family monthly income ≤ 3 000 yuan, multiple births, and more pregnancy complications than that in women aged 21-34 years, in urban areas, and with an education level of high school or above, family monthly income > 3 000 yuan, singleton, and fewer pregnancy complications (P < 0.05). Age, household registration, education level and family income were the risk factors of pregnancy hypothyroidism combined with PE. Conclusion The incidence trend of pregnancy hypothyroidism combined with PE was not stable in Tongzhou District of Beijing from 2015 to 2019, showing strong differences in age, education level, economic level, pregnancy and childbirth times, BMI, and pregnancy complications. It is necessary to fully understand the physical conditions of pregnant women, and to establish a comprehensive prevention and control system.
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In total, 607 bedridden patients aged 60 years and over at Tianlin community hospital and four other hospitals or at home-care in Shanghai were investigated with questionnaire, physical examinations and related laboratory tests. Contents of investigation include general situation, medical conditions, 24-hour recall of diet, intake of nutritional supplement preparation, and so on. As compare to the reference for nutrient intake of the elderly set in the Guide to Diet for Chinese Residents (2007), total nutritional intake was obviously insufficient and three nutrients in diet were imbalanced for most bedridden elderly patients. Intake of most nutrients (including proteins, dietary fiber, calcium, iron, zinc, selenium,copper, magnesium, phosphor, retinol equivalent, vitamin B1 , vitamin B2, vitamin C) was obviously low in bedridden elderly patients, with a larger gap from the requirements of the Dietary Guide.
