Influence of seasonal biorhythms on urinary excretion of enzymes and other parameters.

Urinary excretion of enzymes, electrolytes, creatinine, protein and the consumption of food and water in female and male Wistar rats was examined over two seasons of summer and wintertime, respectively. The evaluation of data revealed that gamma-glutamyltransferase, inorganic phosphate, and the lysosomal enzymes, N-acetyl-beta-D-glucosaminidase and acid phosphatase, were significantly different between the collection periods in both seasons. Other parameters showed significant differences only in male rats, whereas urinary electrolytes, with the exception of chloride, showed no significant differences.