RESUMO
Changes in the physical states, induced with different sous vide cooking temperatures, significantly (P < 0.05) altered lipid bioaccessibility measured in the TNO-simulated gastrointestinal tract model-1 of AAA boneless beef striploin, containing the longissimus lumborum muscle. The denaturation of actin significantly correlates with the total cumulative free fatty acid (FFA) bioaccessibility, whereby the striploin cooked to 60 °C presents the maximum lipid bioaccessibility (15.8 ± 1.0%), rate constant (ka) for FFA hydrolysis (0.087 ± 0.003 min-1), and greatest actin denaturation enthalpy (-0.57 ± 0.06 ΔH). Thus, thermal treatments above 60 °C significantly decrease the kinetics of lipolysis (70 °C = 0.042 ± 0.002 min-1 and 80 °C = 0.047 ± 0.002 min-1) and the resultant total lipid bioaccessibility (70 °C = 8.6 ± 0.7 and 80 °C = 8.3 ± 0.5%). This research highlights the potential to manipulate the physical food structure to alter digestion kinetics, supporting the need to understand supramolecular structures in food and their nutritional outcomes.
Assuntos
Culinária , Lipídeos , Animais , Bovinos , Músculos , TemperaturaRESUMO
Giant congenital melanocytic naevi remain a challenge to clinicians and histopathologists with respect to observation for malignant change and interpretation of histology findings, respectively. We report a 5-year-old boy with a giant bathing trunk naevus who, after multiple previous skin biopsies, developed lymphadenopathy. Biopsy from the lymph nodes demonstrated collections of naevomelanocytes within the lymph node. Interpretation of these findings and subsequent management is discussed.
Assuntos
Nevo Pigmentado/patologia , Neoplasias Cutâneas/patologia , Transformação Celular Neoplásica , Pré-Escolar , Humanos , Metástase Linfática/patologia , Masculino , Nevo Pigmentado/congênito , Neoplasias Cutâneas/congênitoAssuntos
Complicações do Diabetes/tratamento farmacológico , Inibidores Enzimáticos/uso terapêutico , Imunossupressores/uso terapêutico , Metotrexato/uso terapêutico , Necrobiose Lipoídica/tratamento farmacológico , Pentoxifilina/uso terapêutico , Quimioterapia Combinada , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
The use of KDP as a polarization rotator has been limited to small field of view instruments. To investigate this limitation, the index ellipsoid is used to describe the optical properties of KDP and to calculate the retardance and fast axis as a function of the angle of incidence and voltage. Computed converging light patterns are then compared with observed intensity patterns formed by KDP. Finally, computed intensity patterns are used to demonstrate how the field of view of KDP can be increased when properly aligned with a positive uniaxial crystal.
