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1.
BMJ Open ; 12(2): e052778, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-35105577

RESUMO

OBJECTIVE: To explore the relationships between leader support, staff influence over decisions, work pressure and patient satisfaction. DESIGN: A cross-sectional study of large National Health Service (NHS) datasets in England in 2010. SETTING AND PARTICIPANTS: 158 NHS acute hospital trusts in England (n=63 156) from all staff groups. PRIMARY AND SECONDARY OUTCOME MEASURES: Survey data measuring leader support, staff influence over decision making, staff work pressure and objective outcome data measuring patient satisfaction. RESULTS: Multilevel serial mediation analysis showed a significantly positive association between leader support and staff influence over decisions (B=0.74, SE=0.07, p<0.01). Furthermore, staff influence over decisions showed a negative association with staff work pressure (B=-0.84, SE=0.41, p<0.05) which in turn was negatively linked to patient satisfaction (B=-17.50, SE=4.34, p<0.01). Serial mediation showed a positive indirect effect of leader support on patient satisfaction via staff influence over decisions and work pressure (B=10.96, SE=5.55, p<0.05). CONCLUSIONS AND IMPLICATIONS: Our results provide evidence that leader support influences patient satisfaction through shaping staff experience, particularly staff influence over decisions and work pressure. Patients' care is dependent on the health, well-being, and effectiveness of the NHS workforce. That, in turn, is determined by the extent to which leaders are supportive in ensuring that work environments are managed in a way which protects the well-being of staff.


Assuntos
Satisfação do Paciente , Medicina Estatal , Estudos Transversais , Tomada de Decisões , Inglaterra , Humanos
2.
J Organ Behav ; 38(2): 276-303, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28239234

RESUMO

To account for the double-edged nature of demographic workplace diversity (i.e,. relational demography, work group diversity, and organizational diversity) effects on social integration, performance, and well-being-related variables, research has moved away from simple main effect approaches and started examining variables that moderate these effects. While there is no shortage of primary studies of the conditions under which diversity leads to positive or negative outcomes, it remains unclear which contingency factors make it work. Using the Categorization-Elaboration Model as our theoretical lens, we review variables moderating the effects of workplace diversity on social integration, performance, and well-being outcomes, focusing on factors that organizations and managers have control over (i.e., strategy, unit design, human resource, leadership, climate/culture, and individual differences). We point out avenues for future research and conclude with practical implications. © 2015 The Authors. Journal of Organizational Behavior published by John Wiley & Sons, Ltd.

3.
J Appl Psychol ; 102(3): 468-482, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28125256

RESUMO

We review the literature on organizational climate and culture paying specific attention to articles published in the Journal of Applied Psychology (JAP) since its first volume in 1917. The article traces the history of the 2 constructs though JAP has been far more important for climate than culture research. We distinguish 4 main periods: the pre-1971 era, with pioneering work on exploring conceptualization and operationalizations of the climate construct; the 1971-1985 era, with foundational work on aggregation issues, outcome-focused climates (on safety and service) and early writings on culture; the 1986-1999 era, characterized by solidification of a focused climate approach to understanding organizational processes (justice, discrimination) and outcomes (safety, service) and the beginnings of survey approaches to culture; and the 2000-2014 era, characterized by multilevel work on climate, climate strength, demonstrated validity for a climate approach to outcomes and processes, and the relationship between leadership and climate and culture. We summarize and comment on the major theory and research achievements in each period, showing trends observed in the literature and how JAP has contributed greatly to moving research on these constructs, especially climate, forward. We also recommend directions for future research given the current state of knowledge. (PsycINFO Database Record


Assuntos
Liderança , Cultura Organizacional , Publicações Periódicas como Assunto/história , Psicologia Aplicada/história , História do Século XX , História do Século XXI , Humanos
4.
Rev Saude Publica ; 50: 52, 2016 Aug 22.
Artigo em Inglês, Português | MEDLINE | ID: mdl-27556966

RESUMO

OBJECTIVE: To adapt and validate the Team Climate Inventory scale, of teamwork climate measurement, for the Portuguese language, in the context of primary health care in Brazil. METHODS: Methodological study with quantitative approach of cross-cultural adaptation (translation, back-translation, synthesis, expert committee, and pretest) and validation with 497 employees from 72 teams of the Family Health Strategy in the city of Campinas, SP, Southeastern Brazil. We verified reliability by the Cronbach's alpha, construct validity by the confirmatory factor analysis with SmartPLS software, and correlation by the job satisfaction scale. RESULTS: We problematized the overlap of items 9, 11, and 12 of the "participation in the team" factor and the "team goals" factor regarding its definition. The validation showed no overlapping of items and the reliability ranged from 0.92 to 0.93. The confirmatory factor analysis indicated suitability of the proposed model with distribution of the 38 items in the four factors. The correlation between teamwork climate and job satisfaction was significant. CONCLUSIONS: The version of the scale in Brazilian Portuguese was validated and can be used in the context of primary health care in the Country, constituting an adequate tool for the assessment and diagnosis of teamwork. OBJETIVO: Adaptar e validar a escala Team Climate Invetory, de medida do clima de trabalho em equipe, para o idioma português, no contexto da atenção primária à saúde no Brasil. MÉTODOS: Estudo metodológico com abordagem quantitativa de adaptação transcultural (tradução, retrotradução, síntese, comitê de especialistas e pré-teste) e validação com 497 trabalhadores de 72 equipes da Estratégia Saúde da Família no município de Campinas, São Paulo. Verificou-se confiabilidade pelo alfa de Cronbach, validade de construto pela análise fatorial confirmatória pelo software SmartPLS e correlação com escala de satisfação no trabalho. RESULTADOS: Foi problematizado a sobreposição dos itens 9, 11 e 12 do fator participação na equipe e o fator objetivos da equipe no tocante à sua definição. A validação mostrou que não houve sobreposição dos itens e a confiabilidade variou entre 0,92 a 0,93. A análise fatorial confirmatória indicou adequação do modelo proposto com distribuição dos 38 itens nos quatro fatores. A correlação entre clima de trabalho em equipe e satisfação no trabalho foi significativa. CONCLUSÕES: A versão da escala em português falado no Brasil foi validada e pode ser utilizada no contexto da atenção primária à saúde no País, constituindo ferramenta adequada para a avaliação e diagnóstico do trabalho em equipe.


Assuntos
Comparação Transcultural , Equipe de Assistência ao Paciente/organização & administração , Gestão da Segurança , Inquéritos e Questionários , Traduções , Brasil , Humanos , Relações Interpessoais , Satisfação no Emprego , Reprodutibilidade dos Testes
5.
Health Soc Care Community ; 24(3): 309-20, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-25711121

RESUMO

Defining 'effectiveness' in the context of community mental health teams (CMHTs) has become increasingly difficult under the current pattern of provision required in National Health Service mental health services in England. The aim of this study was to establish the characteristics of multi-professional team working effectiveness in adult CMHTs to develop a new measure of CMHT effectiveness. The study was conducted between May and November 2010 and comprised two stages. Stage 1 used a formative evaluative approach based on the Productivity Measurement and Enhancement System to develop the scale with multiple stakeholder groups over a series of qualitative workshops held in various locations across England. Stage 2 analysed responses from a cross-sectional survey of 1500 members in 135 CMHTs from 11 Mental Health Trusts in England to determine the scale's psychometric properties. Based on an analysis of its structural validity and reliability, the resultant 20-item scale demonstrated good psychometric properties and captured one overall latent factor of CMHT effectiveness comprising seven dimensions: improved service user well-being, creative problem-solving, continuous care, inter-team working, respect between professionals, engagement with carers and therapeutic relationships with service users. The scale will be of significant value to CMHTs and healthcare commissioners both nationally and internationally for monitoring, evaluating and improving team functioning in practice.


Assuntos
Serviços Comunitários de Saúde Mental/organização & administração , Transtornos Mentais/terapia , Equipe de Assistência ao Paciente/organização & administração , Inquéritos e Questionários/normas , Comunicação , Continuidade da Assistência ao Paciente/organização & administração , Estudos Transversais , Inglaterra , Humanos , Relações Interprofissionais , Avaliação das Necessidades , Resolução de Problemas , Relações Profissional-Paciente , Psicometria , Reprodutibilidade dos Testes
6.
Rev. saúde pública (Online) ; 50: 52, 2016. tab, graf
Artigo em Inglês | LILACS | ID: biblio-962236

RESUMO

ABSTRACT OBJECTIVE To adapt and validate the Team Climate Inventory scale, of teamwork climate measurement, for the Portuguese language, in the context of primary health care in Brazil. METHODS Methodological study with quantitative approach of cross-cultural adaptation (translation, back-translation, synthesis, expert committee, and pretest) and validation with 497 employees from 72 teams of the Family Health Strategy in the city of Campinas, SP, Southeastern Brazil. We verified reliability by the Cronbach's alpha, construct validity by the confirmatory factor analysis with SmartPLS software, and correlation by the job satisfaction scale. RESULTS We problematized the overlap of items 9, 11, and 12 of the "participation in the team" factor and the "team goals" factor regarding its definition. The validation showed no overlapping of items and the reliability ranged from 0.92 to 0.93. The confirmatory factor analysis indicated suitability of the proposed model with distribution of the 38 items in the four factors. The correlation between teamwork climate and job satisfaction was significant. CONCLUSIONS The version of the scale in Brazilian Portuguese was validated and can be used in the context of primary health care in the Country, constituting an adequate tool for the assessment and diagnosis of teamwork.


RESUMO OBJETIVO Adaptar e validar a escala Team Climate Invetory, de medida do clima de trabalho em equipe, para o idioma português, no contexto da atenção primária à saúde no Brasil. MÉTODOS Estudo metodológico com abordagem quantitativa de adaptação transcultural (tradução, retrotradução, síntese, comitê de especialistas e pré-teste) e validação com 497 trabalhadores de 72 equipes da Estratégia Saúde da Família no município de Campinas, São Paulo. Verificou-se confiabilidade pelo alfa de Cronbach, validade de construto pela análise fatorial confirmatória pelo software SmartPLS e correlação com escala de satisfação no trabalho. RESULTADOS Foi problematizado a sobreposição dos itens 9, 11 e 12 do fator participação na equipe e o fator objetivos da equipe no tocante à sua definição. A validação mostrou que não houve sobreposição dos itens e a confiabilidade variou entre 0,92 a 0,93. A análise fatorial confirmatória indicou adequação do modelo proposto com distribuição dos 38 itens nos quatro fatores. A correlação entre clima de trabalho em equipe e satisfação no trabalho foi significativa. CONCLUSÕES A versão da escala em português falado no Brasil foi validada e pode ser utilizada no contexto da atenção primária à saúde no País, constituindo ferramenta adequada para a avaliação e diagnóstico do trabalho em equipe.


Assuntos
Humanos , Equipe de Assistência ao Paciente/organização & administração , Traduções , Comparação Transcultural , Gestão da Segurança , Brasil , Inquéritos e Questionários , Reprodutibilidade dos Testes , Relações Interpessoais , Satisfação no Emprego
7.
Healthc Policy ; 9(3): 40-54, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24726073

RESUMO

PURPOSE: Evaluate the psychometric properties of the French version of the short 19-item Team Climate Inventory (TCI) and explore the contributions of individual and organizational characteristics to perceived team effectiveness. METHOD: The TCI was completed by 471 of the 618 (76.2%) healthcare professionals and administrative staff working in a random sample of 37 primary care practices in the province of Quebec. RESULTS: Exploratory factor analysis confirmed the original four-factor model. Cronbach's alphas were excellent (from 0.88 to 0.93). Latent class analysis revealed three-class response structure. Respondents in practices with professional governance had a higher probability of belonging to the "High TCI" class than did practices with community governance (36.7% vs. 19.1%). Administrative staff tended to fall into the "Suboptimal TCI" class more frequently than did physicians (36.5% vs. 19.0%). CONCLUSION: Results confirm the validity of our French version of the short TCI. The association between professional governance and better team climate merits further exploration.


Assuntos
Equipe de Assistência ao Paciente/normas , Atenção Primária à Saúde/organização & administração , Psicometria , Inquéritos e Questionários , Adulto , Análise Fatorial , Medicina de Família e Comunidade , Feminino , Humanos , Idioma , Masculino , Pessoa de Meia-Idade , Cultura Organizacional , Garantia da Qualidade dos Cuidados de Saúde , Quebeque , Inquéritos e Questionários/normas
8.
J Trauma Acute Care Surg ; 75(3): 391-7, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23928739

RESUMO

This is a position article from members of the Western Trauma Association (WTA). Because there are no prospective randomized trials on the evaluation and management of peripheral vascular trauma, the algorithm is based on the expert opinion of the WTA members and published observational studies. It may not be applicable at all hospitals caring for injured patients. The algorithm contains letters that correspond to lettered text that is intentionally concise. This Part II algorithm focuses on operative techniques, while the Part I algorithm (J Trauma 2011;70: 1551-1556) emphasized evaluation, diagnosis, and need for operation versus a therapeutic procedure performed in an interventional suite.


Assuntos
Técnicas de Apoio para a Decisão , Procedimentos Cirúrgicos Vasculares/normas , Lesões do Sistema Vascular/cirurgia , Algoritmos , Embolectomia com Balão , Humanos , Procedimentos Cirúrgicos Vasculares/instrumentação , Procedimentos Cirúrgicos Vasculares/métodos , Lesões do Sistema Vascular/diagnóstico
9.
J Health Organ Manag ; 27(1): 134-42, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23734481

RESUMO

PURPOSE: The ubiquity and value of teams in healthcare are well acknowledged. However, in practice, healthcare teams vary dramatically in their structures and effectiveness in ways that can damage team processes and patient outcomes. The aim of this paper is to highlight these characteristics and to extrapolate several important aspects of teamwork that have a powerful impact on team effectiveness across healthcare contexts. DESIGN/METHODOLOGY/APPROACH: The paper draws upon the literature from health services management and organisational behaviour to provide an overview of the current science of healthcare teams. FINDINGS: Underpinned by the input-process-output framework of team effectiveness, team composition, team task, and organisational support are viewed as critical inputs that influence key team processes including team objectives, leadership and reflexivity, which in turn impact staff and patient outcomes. Team training interventions and care pathways can facilitate more effective interdisciplinary teamwork. ORIGINALITY/VALUE: The paper argues that the prevalence of the term "team" in healthcare makes the synthesis and advancement of the scientific understanding of healthcare teams a challenge. Future research therefore needs to better define the fundamental characteristics of teams in studies in order to ensure that findings based on real teams, rather than pseudo-like groups, are accumulated.


Assuntos
Relações Interprofissionais , Equipe de Assistência ao Paciente/organização & administração , Comportamento Cooperativo , Processos Grupais , Humanos , Liderança
10.
J Health Organ Manag ; 27(2): 171-92, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23802397

RESUMO

PURPOSE: The purpose of this paper is to examine the effect of the quality of senior management leadership on social support and job design, whose main effects on strains, and moderating effects on work stressors-to-strains relationships were assessed. DESIGN/METHODOLOGY/APPROACH: A survey involving distribution of questionnaires was carried out on a random sample of health care employees in acute hospital practice in the UK. The sample comprised 65,142 respondents. The work stressors tested were quantitative overload and hostile environment, whereas strains were measured through job satisfaction and turnover intentions. Structural equation modelling and moderated regression analyses were used in the analysis. FINDINGS: Quality of senior management leadership explained 75 per cent and 94 per cent of the variance of social support and job design respectively, whereas work stressors explained 51 per cent of the variance of strains. Social support and job design predicted job satisfaction and turnover intentions, as well as moderated significantly the relationships between quantitative workload/hostility and job satisfaction/turnover intentions. RESEARCH LIMITATIONS/IMPLICATIONS: The findings are useful to management and to health employees working in acute/specialist hospitals. Further research could be done in other counties to take into account cultural differences and variations in health systems. The limitations included self-reported data and percept-percept bias due to same source data collection. PRACTICAL IMPLICATIONS: The quality of senior management leaders in hospitals has an impact on the social environment, the support given to health employees, their job design, as well as work stressors and strains perceived. ORIGINALITY/VALUE: The study argues in favour of effective senior management leadership of hospitals, as well as ensuring adequate support structures and job design. The findings may be useful to health policy makers and human resources managers.


Assuntos
Liderança , Saúde Ocupacional , Administração de Recursos Humanos em Hospitais/normas , Recursos Humanos em Hospital/psicologia , Estresse Psicológico/prevenção & controle , Pessoal Administrativo/psicologia , Pessoal Administrativo/normas , Estudos Transversais , Feminino , Humanos , Relações Interpessoais , Satisfação no Emprego , Masculino , Cultura Organizacional , Administração de Recursos Humanos em Hospitais/métodos , Reorganização de Recursos Humanos , Recursos Humanos em Hospital/normas , Apoio Social , Estresse Psicológico/etiologia , Inquéritos e Questionários , Reino Unido , Carga de Trabalho/psicologia , Carga de Trabalho/normas
11.
J Trauma Acute Care Surg ; 74(5): 1207-12; discussion 1212-4, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23609269

RESUMO

BACKGROUND: The scope of prehospital (PH) interventions has expanded recently--not always with clear benefit. PH crystalloid resuscitation has been challenged, particularly in penetrating trauma. Optimal PH crystalloid resuscitation strategies remain unclear in blunt trauma as does the influence of PH hypotension. The objective was to characterize outcomes for PH crystalloid volume in patients with and without PH hypotension. METHODS: Data were obtained from a multicenter prospective study of blunt injured adults transported from the scene with ISS > 15. Subjects were divided into HIGH (>500 mL) and LOW (≤500 mL) PH crystalloid groups. Propensity-adjusted regression determined the association of PH crystalloid group with mortality and acute coagulopathy (admission International Normalized Ratio, >1.5) in subjects with and without PH hypotension (systolic blood pressure [SBP], <90 mm Hg) after controlling for confounders. RESULTS: Of 1,216 subjects, 822 (68%) received HIGH PH crystalloid and 616 (51%) had PH hypotension. Initial base deficit and ISS were similar between HIGH and LOW crystalloid groups in subjects with and without PH hypotension. In subjects without PH hypotension, HIGH crystalloid was associated with an increase in the risk of mortality (hazard ratio, 2.5; 95% confidence interval [95% CI], 1.3-4.9; p < 0.01) and acute coagulopathy (odds ratio [OR], 2.2; 95% CI, 1.01-4.9; p = 0.04) but not in subjects with PH hypotension. HIGH crystalloid was associated with correction of PH hypotension on emergency department (ED) arrival (OR, 2.02; 95% CI, 1.06-3.88; p = 0.03). The mean corrected SBP in the ED was 104 mm Hg. Each 1 mm Hg increase in ED SBP was associated with a 2% increase in survival in subjects with PH hypotension (OR, 1.02; 95% CI, 1.01-1.03; p < 0.01). CONCLUSION: In severely injured blunt trauma patients, PH crystalloid more than 500 mL was associated with worse outcome in patients without PH hypotension but not with PH hypotension. HIGH crystalloid was associated with corrected PH hypotension. This suggests that PH resuscitation should be goal directed based on the presence or absence of PH hypotension.


Assuntos
Serviços Médicos de Emergência/métodos , Ressuscitação/métodos , Adulto , Soluções Cristaloides , Serviços Médicos de Emergência/estatística & dados numéricos , Feminino , Humanos , Hipotensão/etiologia , Hipotensão/mortalidade , Hipotensão/terapia , Escala de Gravidade do Ferimento , Soluções Isotônicas/uso terapêutico , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Pontuação de Propensão , Modelos de Riscos Proporcionais , Estudos Prospectivos , Soluções para Reidratação/uso terapêutico , Ressuscitação/mortalidade , Ressuscitação/estatística & dados numéricos , Resultado do Tratamento , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/mortalidade , Ferimentos não Penetrantes/terapia
12.
Proc Natl Acad Sci U S A ; 110(9): 3507-12, 2013 Feb 26.
Artigo em Inglês | MEDLINE | ID: mdl-23401516

RESUMO

A cornerstone of modern biomedical research is the use of mouse models to explore basic pathophysiological mechanisms, evaluate new therapeutic approaches, and make go or no-go decisions to carry new drug candidates forward into clinical trials. Systematic studies evaluating how well murine models mimic human inflammatory diseases are nonexistent. Here, we show that, although acute inflammatory stresses from different etiologies result in highly similar genomic responses in humans, the responses in corresponding mouse models correlate poorly with the human conditions and also, one another. Among genes changed significantly in humans, the murine orthologs are close to random in matching their human counterparts (e.g., R(2) between 0.0 and 0.1). In addition to improvements in the current animal model systems, our study supports higher priority for translational medical research to focus on the more complex human conditions rather than relying on mouse models to study human inflammatory diseases.


Assuntos
Genômica , Inflamação/genética , Doença Aguda , Adolescente , Adulto , Animais , Queimaduras/genética , Queimaduras/patologia , Modelos Animais de Doenças , Endotoxemia/genética , Endotoxemia/patologia , Feminino , Regulação da Expressão Gênica , Humanos , Inflamação/patologia , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Transdução de Sinais/genética , Fatores de Tempo , Ferimentos e Lesões/genética , Ferimentos e Lesões/patologia , Adulto Jovem
13.
J Trauma Acute Care Surg ; 73(6): 1395-400, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23064602

RESUMO

BACKGROUND: Acute traumatic coagulopathy (ATC) predicts poor outcome after injury. Females have been demonstrated to be hypercoagulable early in the posttrauma period. It remains unclear whether presence of ATC alters sex-based outcomes after injury. This study's objective was to characterize the sex dimorphism after severe injury in the presence and absence of ATC. METHODS: Data were obtained from a multicenter prospective cohort study of patients with blunt trauma and hemorrhagic shock. ATC was defined as arrival international normalized ratio (INR) of greater than 1.5. Cox regression was used to determine the independent risks of mortality and multiple-organ failure associated with sex in subjects with ATC and without (non-ATC) while controlling for important confounders. The sex mortality differences were characterized over time to determine at what point after injury any differential risks diverge. RESULTS: Of 2,007 enrolled subjects, 1,877 had an arrival INR with 439 (23%) having ATC. There was no difference in incidence of ATC across sex (24% vs. 23%; p = 0.95). In the ATC group, no difference in Injury Severity Score, arrival INR, base deficit, temperature, or 24-hour blood requirements were found across sex. Cox hazard regression revealed that sex was not associated with mortality in non-ATC patients (hazard ratio, 0.94; 95% confidence interval, 0.6-1.5). Female sex was independently associated with mortality only in the ATC group (hazard ratio, 2.04; 95% confidence interval, 1.1-3.9; p = 0.03). These mortality risk differences across sex diverged within the first 24 hours after injury. CONCLUSION: An exaggerated sex dimorphism exists for patients with ATC, with females demonstrating a twofold higher independent risk of mortality. These differential mortality risks across sex diverge early after injury, suggesting that they may be caused by an ongoing hemorrhage. Females who present with ATC at admission have a significantly greater risk of poor outcome. Further studies are warranted to explore the mechanisms responsible for sex dimorphism in the setting of ATC. LEVEL OF EVIDENCE: Prognostic study, level II.


Assuntos
Transtornos da Coagulação Sanguínea/etiologia , Ferimentos não Penetrantes/sangue , Adulto , Transtornos da Coagulação Sanguínea/sangue , Transtornos da Coagulação Sanguínea/epidemiologia , Feminino , Humanos , Escala de Gravidade do Ferimento , Coeficiente Internacional Normatizado , Masculino , Pessoa de Meia-Idade , Insuficiência de Múltiplos Órgãos/etiologia , Insuficiência de Múltiplos Órgãos/mortalidade , Modelos de Riscos Proporcionais , Estudos Prospectivos , Fatores de Risco , Fatores Sexuais , Choque Hemorrágico/sangue , Choque Hemorrágico/etiologia , Choque Hemorrágico/mortalidade , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/mortalidade , Adulto Jovem
15.
Ann Surg ; 255(5): 993-9, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22470077

RESUMO

OBJECTIVE: To determine and compare outcomes with accepted benchmarks in trauma care at 7 academic level I trauma centers in which patients were treated on the basis of a series of standard operating procedures (SOPs). BACKGROUND: Injury remains the leading cause of death for those younger than 45 years. This study describes the baseline patient characteristics and well-defined outcomes of persons hospitalized in the United States for severe blunt trauma. METHODS: We followed 1637 trauma patients from 2003 to 2009 up to 28 hospital days using SOPs developed at the onset of the study. An extensive database on patient and injury characteristics, clinical treatment, and outcomes was created. These data were compared with existing trauma benchmarks. RESULTS: The study patients were critically injured and were in shock. SOP compliance improved 10% to 40% during the study period. Multiple organ failure and mortality rates were 34.8% and 16.7%, respectively. Time to recovery, defined as the time until the patient was free of organ failure for at least 2 consecutive days, was developed as a new outcome measure. There was a reduction in mortality rate in the cohort during the study that cannot be explained by changes in the patient population. CONCLUSIONS: This study provides the current benchmark and the overall positive effect of implementing SOPs for severely injured patients. Over the course of the study, there were improvements in morbidity and mortality rates and increasing compliance with SOPs. Mortality was surprisingly low, given the degree of injury, and improved over the duration of the study, which correlated with improved SOP compliance.


Assuntos
Benchmarking , Avaliação de Resultados em Cuidados de Saúde , Procedimentos Cirúrgicos Operatórios/normas , Ferimentos não Penetrantes/cirurgia , APACHE , Adulto , Estado Terminal , Feminino , Mortalidade Hospitalar , Humanos , Masculino , Insuficiência de Múltiplos Órgãos/epidemiologia , Ferimentos não Penetrantes/mortalidade , Adulto Jovem
16.
Crit Care Med ; 40(4): 1129-35, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22020243

RESUMO

OBJECTIVES: To describe the incidence of postinjury multiple organ failure and its relationship to nosocomial infection and mortality in trauma centers using evidence-based standard operating procedures. DESIGN: Prospective cohort study wherein standard operating procedures were developed and implemented to optimize postinjury care. SETTING: Seven U.S. level I trauma centers. PATIENTS: Severely injured patients (older than age 16 yrs) with a blunt mechanism, systolic hypotension (<90 mm Hg), and/or base deficit (≥6 mEq/L), need for blood transfusion within the first 12 hrs, and an abbreviated injury score ≥2 excluding brain injury were eligible for inclusion. MEASUREMENTS AND MAIN RESULTS: One thousand two patients were enrolled and 916 met inclusion criteria. Daily markers of organ dysfunction were prospectively recorded for all patients while receiving intensive care. Overall, 29% of patients had multiple organ failure develop. Development of multiple organ failure was early (median time, 2 days), short-lived, and predicted an increased incidence of nosocomial infection, whereas persistence of multiple organ failure predicted mortality. However, surprisingly, nosocomial infection did not increase subsequent multiple organ failure and there was no evidence of a "second-hit"-induced late-onset multiple organ failure. CONCLUSIONS: Multiple organ failure remains common after severe injury. Contrary to current paradigms, the onset is only early, and not bimodal, nor is it associated with a "second-hit"-induced late onset. Multiple organ failure is associated with subsequent nosocomial infection and increased mortality. Standard operating procedure-driven interventions may be associated with a decrease in late multiple organ failure and morbidity.


Assuntos
Insuficiência de Múltiplos Órgãos/etiologia , Choque Hemorrágico/etiologia , Ferimentos não Penetrantes/complicações , Adulto , Infecção Hospitalar/epidemiologia , Infecção Hospitalar/etiologia , Feminino , Mortalidade Hospitalar , Humanos , Incidência , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Insuficiência de Múltiplos Órgãos/epidemiologia , Modelos de Riscos Proporcionais , Estudos Prospectivos , Choque Hemorrágico/complicações , Centros de Traumatologia/normas , Centros de Traumatologia/estatística & dados numéricos
17.
J Exp Med ; 208(13): 2581-90, 2011 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-22110166

RESUMO

Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well as in healthy subjects receiving low-dose bacterial endotoxin, and show that these severe stresses produce a global reprioritization affecting >80% of the cellular functions and pathways, a truly unexpected "genomic storm." In severe blunt trauma, the early leukocyte genomic response is consistent with simultaneously increased expression of genes involved in the systemic inflammatory, innate immune, and compensatory antiinflammatory responses, as well as in the suppression of genes involved in adaptive immunity. Furthermore, complications like nosocomial infections and organ failure are not associated with any genomic evidence of a second hit and differ only in the magnitude and duration of this genomic reprioritization. The similarities in gene expression patterns between different injuries reveal an apparently fundamental human response to severe inflammatory stress, with genomic signatures that are surprisingly far more common than different. Based on these transcriptional data, we propose a new paradigm for the human immunological response to severe injury.


Assuntos
Queimaduras/metabolismo , Regulação da Expressão Gênica , Genoma Humano , Leucócitos/metabolismo , Transcrição Gênica , Imunidade Adaptativa , Adulto , Queimaduras/imunologia , Queimaduras/patologia , Estado Terminal , Endotoxinas/administração & dosagem , Feminino , Humanos , Imunidade Inata , Inflamação/imunologia , Inflamação/metabolismo , Inflamação/patologia , Leucócitos/imunologia , Masculino , Índices de Gravidade do Trauma
18.
Health Serv Manage Res ; 24(4): 203-12, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22040948

RESUMO

Membership in well-structured teams, which show clarity in team and individual goals, meet regularly, and recognize diverse skills of their members, is known to reduce stress. This study examined how membership of well-structured teams was associated with lower levels of strain, when testing a work stressors-to-strains relationship model across the three levels of team structure, namely well-structured, poorly structured (do not fulfill all the criteria of well-structured teams) and no team. The work stressors tested, were quantitative overload and hostile environment, whereas strains were measured through job satisfaction and intention to leave job. This investigation was carried out on a random sample of 65,142 respondents in acute/specialist National Health Service hospitals across the UK. Using multivariate analysis of variance, statistically significant differences between means across the three groups of team structure, with mostly moderate effect sizes, were found for the study variables. Those in well-structured teams have the highest levels of job satisfaction and the least intention to leave job. Multigroup structural equation modelling confirmed the model's robustness across the three groups of team structure. Work stressors explained 45%, 50% and 65% of the variance of strains for well-structured, poorly structured and no team membership, respectively. An increase of one standard deviation in work stressors, resulted in an increase in 0.67, 0.70 and 0.81 standard deviations in strains for well-structured, poorly structured and no team membership, respectively. This investigation is an eye-opener for hospitals to work towards achieving well-structured teams, as this study shows weaker stressor-to-strain relationships for members of these teams.


Assuntos
Comportamento Cooperativo , Exposição Ocupacional/prevenção & controle , Recursos Humanos em Hospital , Estresse Psicológico/prevenção & controle , Adulto , Feminino , Humanos , Satisfação no Emprego , Masculino , Pessoa de Meia-Idade , Medicina Estatal , Inquéritos e Questionários , Reino Unido
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