Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition.

OBJECTIVE: The objective was to investigate the impact of a verbal memory training task on psychiatric symptoms and cognition in schizophrenia. METHOD: As part of a larger, 6-month cognitive remediation program, 57 patients with schizophrenia were randomly assigned to receive performance-based, hierarchical training on a verbal memory task based on a dichotic listening (DL) with distracter paradigm. These patients were compared with 68 patients who had been randomly assigned to a control condition. RESULTS: Training on the DL task was not associated with changes in general psychopathology or auditory hallucinations (AH) specifically. Training was associated with improvements in verbal memory, but not attention. CONCLUSION: The current investigation adds to the growing literature on the effectiveness of cognitive remediation training and indicates that training on the DL task enhances verbal episodic memory. The results do not support the use of DL training as a method for reducing AH.

Memory and executive function impairments in deficit syndrome schizophrenia.

The relationship between deficit syndrome schizophrenia, as determined by the Schedule for the Deficit Syndrome, and impairments in memory and executive function was investigated by administering the Wisconsin Card Sorting Test, the Wechsler Adult Intelligence Test, and the Wechsler Memory Scales to outpatients with deficit (n=33) and non-deficit (n=57) syndrome. A factor analysis of test variables revealed three factors: executive functioning; simple verbal memory; and semantic verbal memory. Results indicated that the deficit group performed significantly worse on the executive functioning factor, but not on either of the verbal memory factors. These findings support the hypothesis that deficit syndrome schizophrenia represents a specific cognitive impairment in executive processing and not necessarily graver global cognitive impairment.