Dance for Multiple Sclerosis: A Systematic Review.

BACKGROUND: Evidence of the benefits of dance for people with Parkinson disease is well established, but only recently has dance been investigated for people with multiple sclerosis (MS). The purpose of this review was to identify and evaluate the feasibility and effectiveness of dance interventions to improve functional, psychosocial, and participation outcomes in people with MS. METHODS: Eight databases and gray literature sources were searched from inception to March 2022. Quantitative, mixed-methods, and qualitative studies evaluating dance interventions for adults with MS were included. Included studies were critically appraised using the Mixed Methods Appraisal Tool, and results were analyzed through a parallel-results convergent synthesis. RESULTS: Thirteen studies were included, with a total of 174 participants. Various dance genres were investigated, and only 1 mild adverse event was reported. Four to 12 weeks of twice-weekly, 60-minute dance sessions were feasible in those with mild to moderate relapsing-remitting MS. Positive effects were identified mainly in motor outcomes, with qualitative themes indicating psychological and social benefits. CONCLUSIONS: A variety of dance interventions are likely feasible and potentially beneficial for people with mild to moderate relapsing-remitting MS, but studies were generally of low-moderate quality. High-quality studies are needed to determine the effectiveness of dance interventions for people with MS, including those with progressive forms of MS and higher levels of disability.

PSTPIP1-associated myeloid-related proteinaemia inflammatory (PAMI) syndrome; a case presenting as a perinatal event with early central nervous system involvement?

BACKGROUND: We report a three-year-old girl with a potentially unique phenotype of perinatal onset and neurovascular features who was found to have PAMI syndrome. We also compare her case to those previously reported and review the differences between the PSTPIP1-associated inflammatory diseases (PAID) phenotypes and genotypes. CASE PRESENTATION: The patient was found to have a heterozygous pathogenic variant in PSTPIP1 (c.748G > A p.E250K). This variant was shown to be absent in both parents and therefore de novo in the patient. A literature review was carried out through multiple databases using the terms PSTPIP1, PAID, PAPA syndrome and PAMI syndrome. This information was collected and used to form comparisons between the current literature and our reported case. CONCLUSIONS: Our case contributes to the literature on PAMI syndrome whilst providing an example of a potentially unique clinical phenotype, giving insight into the pre-symptomatic phase of the condition. We highlight the importance of considering PAMI syndrome in the differential for early onset unexplained inflammation. In addition, we explore the possibility that perinatal neurovascular events could be an early feature of PAMI syndrome.

Movement for multiple sclerosis: a multi-site partnership for practice and research.

While dance programs for people with Parkinson's disease (PD) have been developed globally over the past two decades, dance programs for people with multiple sclerosis (MS) are just emerging. This article introduces three dance for MS programs and a multi-site partnership that was developed to evaluate and advance a model for dance for MS programs. The program partners convened over 2 days to share program models, consider current and planned program evaluations, and identify unique challenges and promising practices for delivering safe and effective dance for MS programs. This paper presents the findings of this convening and recommendations for dance for MS programs.Background:While dance programs for people with Parkinson's disease (PD) have been developed globally over the past two decades, dance programs for people with multiple sclerosis (MS) are just emerging. This article introduces three dance for MS programs and a multi-site partnership that was developed to evaluate and advance a model for dance for MS programs.Methods: The program partners convened over 2 days to share program models, consider current and planned program evaluations, and identify unique challenges and promising practices for delivering safe and effective dance for MS programs.Results:A set of promising practices for dance for MS programs, including recommendations for partnership, dance and movement approaches, and environmental, physical and psychosocial considerations, was developed by the program partners.Conclusions: These programs suggest that dance may be a useful modality for people with MS. Recommendations are offered to guide safe and evidence-based dance for MS practices.