RESUMO
Sleep disordered breathing, especially obstructive sleep apnea, are common in cardiovascular disease. Negative hemodynamic effects are mediated by nocturnal ischemia and intrathoracal pressure swings. Therefore "therapy resistant" arterial hypertension and congestive heart failure, as well as atrial fibrillation or sleep associated bradycardia are suggestive of sleep disordered breathing. Further on, clinical course of coronary artery disease seems to be influenced by nocturnal breathing disorders. Application of continuous positive airway pressure (CPAP) is effective in most of the patients and attenuates cardiodepressive hemodynamic effects of obstructive sleep apnea.
Assuntos
Cardiopatias/diagnóstico , Cardiopatias/terapia , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/terapia , Cardiopatias/etiologia , Humanos , Apneia Obstrutiva do Sono/complicaçõesRESUMO
Growing evidence suggests that there may be a strong pathophysiologic link between congestive heart failure (CHF) and nocturnal breathing disorders due to nocturnal oxygen desaturation, intrathoracic pressure swings and sympathetic activation. It seems that sleep apnea contributes to systolic and diastolic heart failure, reduced left and right ventricular function and arrhythmia (e.g. atrial fibrillation). Therefore treatment of sleep apnea might alleviate cardiac symptoms and improve cardiac function. Nevertheless, the exact role of long term treatment of sleep apnea in heart failure patients remains to be elucidated.
