RESUMO
Twenty-eight eyes were followed prospectively by goniophotography after cataract surgery. Ten had no intraocular lens (IOL), ten had the "Azar 91Z" lens implanted and eight had the Cilco "Optiflex" lens inserted. Iris-haptic synechia or burial occurred in 9 of 10 of the "91Z" group and three of eight of the "Optiflex" lenses. These changes developed predominantly in the inferior angle and were seen as soon as 4 weeks postoperatively. Based on this data, preoperative gonioscopy is recommended prior to removal of these IOLs. Cutting buried haptics and leaving them within iris stroma may be a safe surgical alternative which avoids undue trauma to the anterior segment.
Assuntos
Lentes Intraoculares , Seguimentos , Gonioscopia , Humanos , Irite/etiologia , Lentes Intraoculares/efeitos adversos , Fotografação , Estudos Prospectivos , Fatores de TempoRESUMO
Corneal epithelial erosions developed in two patients wearing gas permeable contact lenses (Boston) soon after commencing topical timolol maleate therapy. This prompted the following investigation. Forty rabbit corneas were examined by scanning and transmission electron microscopy after treatment for one month with one of the following: timolol ophthalmic solution, preservative-free timolol, contact lens, contact lens and timolol, contact lens and preservative-free timolol, contact lens and saline, or no treatment. Corneas treated with either timolol or contact lens alone showed mild to moderate edema or degeneration of epithelial and endothelial cells. However, the combined use of a contact lens and timolol produced marked alterations in both the corneal epithelium and endothelium.
Assuntos
Lentes de Contato/efeitos adversos , Córnea/efeitos dos fármacos , Doenças da Córnea/etiologia , Timolol/administração & dosagem , Administração Tópica , Animais , Córnea/ultraestrutura , CoelhosRESUMO
Corneal epithelial dysplasia and carcinoma in situ have not been emphasized as distinct clinical conditions in the literature. Seven cases are presented with their clinicopathological correlation. Six of the patients presented primarily with corneal signs and symptoms consisting of notable visual blurring or foreign body sensations, or both. Biomicroscopic examination revealed a geographic, diffuse, greyish-white haze involving the corneal epithelium, often with; subtle thickening and irregularity of the involved areas and overlying superficial punctate keratitis. Histologic examination showed all degree of corneal epithelial dysplasia up to carcinoma in situ. The diagnosis, course and management of these conditions is discussed.
Assuntos
Carcinoma in Situ/patologia , Doenças da Córnea/patologia , Neoplasias Oculares/patologia , Adulto , Idoso , Doença de Bowen/patologia , Córnea/patologia , Epitélio/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
A tapioca melanoma in a 75-year-old Caucasian man was shown by light microscopy to consist of spindle B cells with abundant vesicular cytoplasm, minimal pigmentation and surface nodularity that correlated with the gross appearance. Electron microscopy showed spindle shaped cells with multiple premelanosomes and melanin granules. Iris angiography demonstrated an irregular crisscrossing vascular network with a papillary configuration and fluorescein leakage confined to the tumour. The clinical appearance of the lesion and the angiographic findings are characteristic of this unusual variant of iris melanoma and help distinguish it from granulomatous iritis and from neurofibroma, leiomyoma and metastatic carcinoma of the iris.
