[An attempt to precise indications for treatment with systemic cryotherapy of patients with rheumatoid arthritis]. / Próba sprecyzowania wskazan dla leczenia krioterapia ogólnoustrojowa chorych na reumatoidalne zapalenie stawów.

The prospective studies included 178 patients (43 men and 135 women) aged 30 to 68 years, treated because of rheumatoid arthritis (R.A.). All of them were subjected to systemic cryotherapy, considerin the total antioxidant states in the serum registered before and after the cryotherapic treatment. Fluctuations of serum antioxidants were referred to selected clinical factors such as: sex, age, duration and progression of the disease. It was confirmed that among patients with R.A., the most beneficial clinical effects obtained through systemic cryotherapy may be expected in women aged up to 49 years, in whom the disease lasted no longer than 3 years and is in the Ist of IInd period (phase).

[Real profits of CKMBmass determination in early differentiation of acute coronary syndrome in patients admitted to the emergency unit]. / Praktyczne wykorzystanie oznaczania CKMBmass we wczesnym róznicowaniu postaci ostrego zespolu wiencowego u chorych zglaszajacych sie do Izby Przyjec Oddzialu Ratunkowego.

The aim of this study was to evaluate actual diagnostic profits of CKMBmass concentration in diagnosis of acute myocardial infarction (AMI) in the group of patients admitted to the Emergency Unit with stenocardia and comparison to CKMB activity test. The study carried out in a group of 53 patients admitted to the Emergency Unit of 5-th Military Hospital in Krakow. The study group consisted of 28 (52.8%) of patients with acute myocardial infarction and 25 (47.2%) with unstable angina pectoris. It was found that diagnostic sensitivity of both parameters (CKMBmass 70.8% and CKMB 67.8%) are equivalent for early diagnosis of acute coronary syndrome in the Emergency Unit.

[The chronic DIC associated with the neoplastic disease in patients of an advanced age]. / Przewlekly DIC towarzyszacy chorobie nowotworowej u chorych w starszym wieku.

The analysis included 80 patients (48 men and 32 women) aged 65 to 87 years, treated because of cancer of the stomach (34 causes) or of the large bowel (46 causes). In all the patients as well as in a control group made up of persons who were treated because of non-neoplastic diseases of the gastrointestinal tract the determinations were conducted of selected coagulological parameters: fibrinogen and D-dimer concentration, antithrombin III (AT III) activity, kaolin-cephalin index (APTT), prothrombin (PT), thrombin time (TT) and number of thrombocytes in the blood. The analysis of the results obtained showed that hemostasis disturbances of a chronic DIC character occur in 82.5% of persons of an advanced age ill with a cancer of the stomach or of the large bowel.

[The efficacy of the Helicobacter pylori eradication in people of an advanced age]. / Skutecznosc eradykacji zakazenia Helicobacter pylori u ludzi w starszym wieku.

In a group of 112 patients aged 65 to 72 years with chronic gastritis (48 persons), a peptic ulcer (30 persons), a duodenal ulcer (34 persons) bacteriological examinations were conducted aiming at determining the sensitivity to antibiotics of Helicobacter pylori (H. pylori) strains isolated from the month (gingival pockets), the stomach or duodenal mucous, from stool samples and from the skin of the hands. The sensitivity to antibiotics was tested with the diffusive-disc method taking into consideration 23 chemotherapeutic agents. It was shown that with the use of single antibiotics the chance of efficiently elimination the H. pylori infection from the area of the whole alimentary canal (month, stomach, duodenum, large bowel) amounted to 14.3-35.7% depending on the chemotherapeutics used, where with the use of a two-medicine therapy (metronidazol + amoxycillin) it increased to 42.9%. This means that in people of an advanced age the chemotherapy carried out with the aim of liquidating the infection in the stomach or duodenum mucousa creates possibilities for the H. pylori infection to persist in other parts of the alimentary canal ranging from 64.3 to 85.7%. This way the patient treated may then undergo self-infection as well as be a source of infection for other persons.

Comparative diagnostic value of the breath test and the urine test with 14C-urea in the detection of the Helicobacter pylori infection.

Among 92 patients with chronic gastritis we conducted a synchronous diagnosis of the Helicobacter pylori (H. pylori) infection using a culture and a serological test (IFP), in conjunction with breath and urine tests involving (14)C-urea (BTU-C14 and UTU-C14). The infection was confirmed by isolation in 71 persons (77.2%), the presence of specific IgG in the blood serum was found in 75 (81.5%). In comparison, the BTU-C14 indicated a group of 77 people (83.7%) as infected, and the UTU-C14 a group of 76 (82.6%). In order to determine the diagnostic value (sensitivity, specificity and efficiency) of the latter tests, the results were compared with those of the culture and of the serological tests. It was found that the BTU-C14 test used showed a 100% sensitivity, a 89.5% specificity and a 97.9% efficiency. The UTU-C14 test showed a 100.0% sensitivity, a 94.4% specificity and a 98.9% efficiency in the detection of the H. pylori infection.