Current status of bone graft options for anterior interbody fusion of the cervical and lumbar spine.

Anterior cervical discectomy and fusion (ACDF) and anterior lumbar interbody fusion (ALIF) are common surgical procedures for degenerative disc disease of the cervical and lumbar spine. Over the years, many bone graft options have been developed and investigated aimed at complimenting or substituting autograft bone, the traditional fusion substrate. Here, we summarise the historical context, biological basis and current best evidence for these bone graft options in ACDF and ALIF.

Cervical myelopathy associated with congenital C2/3 canal stenosis and deficiencies of the posterior arch of the atlas and laminae of the axis: case report and review of the literature.

STUDY DESIGN: A case report of a young male suffering progressive neurologic dysfunction associated with a previously unreported combination of structural bony abnormalities. A review of the literature is also presented. OBJECTIVE: To describe a unique presentation of cervical myelopathy related to posterior deficiencies of the atlas and axis, and to report on the successful management of this case. SUMMARY OF BACKGROUND DATA: Cervical myelopathy from congenital canal stenosis is an uncommon presentation in the adolescent age group, especially affecting the C2/3 level. Aplasia of the atlas is a rare, although well-reported phenomena. Defects of the posterior elements of the axis are similarly uncommon. A combination of the 2 defects in the 1 patient has not previously been recorded. METHODS: A 14-year-old Caucasian male with no history of trauma or neck pain presented with progressive cervical myelopathy over a 2-year period. Plain radiograph and computed tomography revealed congenital aplasia of the posterior arch of the atlas and bilateral cleft defects of the laminae of the axis resulting in a free floating C2 spinous process. Magnetic resonance imaging showed T1 and T2 signal abnormality at the C2-C3 level, with C2/3 congenital canal stenosis and mild disc protrusion. RESULTS: The patient underwent a posterior decompression and lateral mass fixation at the C2/3 articulation to preserve maximal motion segments. At 12-month follow-up, the patient's cervical myelopathy had improved in terms of gait dysfunction and hemiparesis. Fusion was evident across the posterior lateral mass on radiologic investigation. CONCLUSION: Posterior deficiencies of the atlas and axis are rare occurrences in isolation, let alone in the 1 patient. This report broadens the radiographic differential diagnosis of patients presenting with cervical myelopathy, which has been associated with congenital posterior C2 anomalies in only a handful of patients. Surgery is an appropriate option for these patients faced with progressive neurologic dysfunction.