Reduction of nitro group on derivative of 1,8-napthalimide for quantitative detection of hydrogen sulfide.

A fluorescence "turn-on" sensor (HSS) for detection of H2S was developed on the basis of NO2-NH2 reduction. HSS showed a high affinity and sensitivity to H2S over other reducing reagents, particularly for biothiols. Also, the short responding time and high linear dependence between fluorescence enhancement and H2S concentration had HSS behave as a rapid sensor for quantitatively detection of H2S in the biological level.

Investigation of desilylation in the recognition mechanism to fluoride by a 1,8-naphthalimide derivative.

A reaction-based chemosensor (AF-1) was designed, synthesized and applied as an optical approach for quantitative measurement of F(-) in MeCN. In the presence of F(-), selective fluoride-assisted desilylation instantly gave colorimetric and fluorogenic signals, providing a dual-optical channel for the detection of F(-). (1)H NMR titration was carried out to investigate the desilylation process, revealing F(-) triggered rapid cleavage of Si-O bond in trimethylsilyl ether. AF-1 exhibited high sensitivity and selectivity to F(-) over other anions. The detection limit to F(-) was calculated to be 0.05 ppm.