Decoding and comprehension skills mediate the link between a small-group reading programme and English national literacy assessments.

BACKGROUND: Despite the fact that literacy instruction is a main focus of primary education, many children struggle to meet nationally set standards. AIMS: We aimed to test which components of a comprehensive reading programme (ABRACADABRA: https://eur03.safelinks.protection. OUTLOOK: com/?url=https%3A%2F%2Fdoi.org%2F10.1186%2FISRCTN18254678&data=04%7C01%7Cjanet.vousden%40ntu.ac.uk%7C880280e0b00749df855308d94068a0bb%7C8acbc2c5c8ed42c78169ba438a0dbe2f%7C1%7C0%7C637611640381216902%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=%2B4U9sGfofkyCPEY7lWz8n3TPoMOAeJMXyFwdhW6EpUw%3D&reserved=0) mediated the effect of the programme on nationally assessed literacy outcomes. SAMPLE: Following blind allocation, 516 Year 1 pupils from 40 schools were randomized to the programme group, and 908 Year 1 pupils, to a control condition. METHODS: Pupils in the programme completed 20 weeks of instruction in grapheme/phoneme knowledge, decoding, and comprehension. Control children received regular classroom instruction. RESULTS: Children in the programme group were significantly better at these taught skills after the programme finished (effect sizes: grapheme/phoneme knowledge, ß = .33, 95% CI [0.09-0.57]; decoding, ß = .26, 95% CI [0.09-0.43]; and comprehension, ß = .26, 95% CI [0.05-0.47]). Improvements in the programme group's decoding and comprehension skills fully mediated the improvements in national literacy assessments serving as a delayed post-test 12 months after the programme. Programme group pupils were 2.3 (95% CI [1.4-4.1]) times more likely to achieve/exceed the expected standard in reading, and 1.8 (95% CI [1.2-2.6]) times more likely to achieve/exceed the expected standard in writing due to an increase in the trained skills. CONCLUSIONS: These results provide strong evidence that a programme that incorporates decoding and comprehension instruction for typically developing beginning readers improves distal educational outcomes in reading and writing through increasing proficiencies targeted by the reading programme.

Orthographic Knowledge and Clue Word Facilitated Spelling in Children With Developmental Language Disorder.

Purpose This study investigated the orthographic knowledge and how orthographic and phonological information could support children with developmental language disorder (DLD) to make more accurate spelling attempts. Method Children with DLD (N = 37) were matched with chronological age-matched (CAM) children and language age-matched children. These children completed specific and general orthographic knowledge tasks as well as spelling task conditions with either no clue word (pretest), a phonological clue word, or an orthographic clue word. Results Children with DLD were significantly less accurate in their specific orthographic knowledge, compared with CAM children, but had similar scores for general orthographic knowledge to CAM children. Children with DLD and both controls had significantly higher spelling scores in the orthographic clue word condition compared with a pretest pseudoword spelling task. Conclusions Children with DLD acquire the general knowledge of a written language's orthography but, possibly through less print exposure, have less well-represented word-specific orthographic knowledge. Moreover, children with DLD are able to extract the orthographic features of a clue word and employ these to produce more accurate spellings. These findings offer support for a spelling intervention approach based on orthography.

Respiratory surveillance in mineral dust-exposed workers.

Recently, there has been a worldwide resurgence in pneumoconiosis, or pulmonary fibrosis due to occupational mineral dust exposure. In Queensland, Australia, there has been a re-emergence of coal workers' pneumoconiosis and silicosis. Some coal mining communities have experienced a resurgence of progressive massive fibrosis in the USA and a worldwide epidemic is occurring of accelerated silicosis due to exposure to artificial stone. These diseases are all preventable and should not be occurring in the 21st century. Best practice prevention includes reduction of exposure to mineral dusts or, ideally, prevention of exposure altogether. However, where dust exposure has occurred, respiratory surveillance can provide a strategy for early disease detection. It is important to identify early signs of occupational lung disease at a stage where intervention may be beneficial, though it must be acknowledged that progression may occur even after cessation of exposure to dusts. Respiratory surveillance should be distinguished from population screening and case finding, which are different methods used for disease investigation and control. Designing an ideal respiratory surveillance programme is challenging, as there is no single test that accurately identifies early disease. Several different respiratory disorders may occur related to the same exposure(s). Physicians organising and interpreting tests used in respiratory surveillance must be aware of the broad range of potential work-related respiratory conditions, complexities in diagnosis, and appropriate interpretation of the exposure history, as well as current management options. A working knowledge of the compensation and medicolegal avenues available to workers in individual jurisdictions is also useful. KEY POINTS: Mineral dust exposure causes a number of conditions, including those specific to dust exposures, such as the pneumoconioses (or pulmonary fibroses due to mineral dust exposure), and others that may additionally be related to other causes, such as COPD.Identification of multiple conditions using respiratory investigations requires expert interpretation and understanding of the range of potential conditions.The frequency and content of a respiratory surveillance programme will vary according to the relevant occupational exposures, and be affected by both medical and nonmedical factors, including the background prevalence of local diseases. A programme will also need to consider other factors such as local legislation, availability of resources, worker convenience and cost. EDUCATIONAL AIMS: To identify the large range of respiratory diseases caused by exposure to mineral dusts and identify the range of tests that may be used in a surveillance programme for occupational respiratory disorders.To highlight difficulties that might be experienced by medical practitioners in designing and operating an effective surveillance programme, while incorporating rapidly advancing medical technology and practice.

Supplement Use and Behaviors of Athletes Affiliated With an Australian State-Based Sports Institute.

The authors aimed to update knowledge of the use of supplements among Australian athletes at a state-based sports institute. The authors conducted a cross-sectional survey using an online questionnaire to assess the influence of age, sports category, and scholarship category on supplement use. Of 94 completed questionnaires, 82 (87%) indicated supplements in the previous 12 months (mean = 4.9 ± 3.3). No significant difference in supplement usage rate was identified when considering age, scholarship category, or sport category. The most frequently used supplements were sports drinks (70%), caffeine (48%), protein powder (42%), and sports bars (42%). Recovery (63%), health maintenance (59%), and improved energy (50%) were the most frequently reported rationale to use supplements. Allied health professionals and credible online resources were the predominant sources of influence regarding use. However, athletes from lower scholarship categories were more likely to have social media, parents, and siblings influence usage, and age was inversely related to increased influence from parents, social media, physicians not associated with the institute, the Internet, and siblings. Older athletes and those on higher scholarships were more likely to source supplements from training facilities and sports nutrition staff outside of the institute or direct from a supplier, whereas those on lower scholarships tended to rely more on family and friends for their supplements. Findings from this study show a high prevalence of supplement use and are the first to show an influence of social media, particularly in younger athletes. Opportunities exist to optimize how athletes are informed regarding supplement use and organizational and supplement policy.

Developing a Visual Attention Assessment for Children at School Entry.

Whereas young children's visual attention has been explored in a number of previous studies, so far it has not been investigated by an assessment based on Bundesen's Theory of Visual Attention (TVA). TVA is a prominent visual attention model that has been widely used as foundation in studies targeting older children, adolescents or adults. In this paper we explore the utility of adopting TVA to explore the visual attention of 4- to 5- year olds and present the development of a simplified adapted version of a TVA-based assessment designed for this age group. Key assessment alterations included the substitution of letter stimuli with black and white symbols and the reduction of assessment duration. The suitability of the assessment for the target age group was subsequently tested in two consecutive studies (Study I: N = 43; Study II: N = 24). Study results show that measuring visual attention based on a simplified TVA-based assessment appears feasible in such a young age group, provided that the study design takes into account the capabilities of these young children. The authors argue that by adopting this kind of visual attention assessment the relationship between visual attention development and early learning could be better understood.

Successful Heart Transplant after Ten Hours Out-of-body Time using the TransMedics Organ Care System.

OBJECTIVE: We report the successful transplantation of a heart following an out-of-body time of 611 minutes into a recipient with dilated cardiomyopathy and left ventricular assist device implant. PATIENTS: Our patient was urgently waiting for a cardiac transplant whilst receiving LVAD support. Recurrent VF and repeated AICD shocks necessitated this action. RESULTS: Although requiring ECMO and inotropic support in the first 17 hours post-transplant, the patient was discharged from hospital on day 15 post-transplant with normal cardiac function. CONCLUSION: We report some of the salient points of the process and discuss the utility of this technology to an Australian transplant unit.

Deservingness and gratitude in the context of heart transplantation.

Heart transplantation is now routinely offered as a treatment for end-stage heart failure, and the "gift-of-life" metaphor has become pervasive in this context, forming the foundation on which transplantation discourses rest. In this article, we question organ-as-gift understandings of transplantation. One can also legitimately think of the transplanted organ as a donation, with distinct implications in terms of the transplantation experience for the recipient. We explored the transplantation experience of 13 heart recipients in Australia. We conducted semistructured interviews, and our interpretative phenomenological analysis of the data resulted in three themes: deservingness, nuances of gratitude, and giving forward. Our results indicate that differences between organ-as-gift and organ-as-donation understandings of transplantation are more than merely semantic. Organ-as-donation understandings raise the issue of deservingness, with recipients' assessments of their worthiness influencing their posttransplant experience of gratitude and, ultimately, the meaning(s) gleaned from their transplant experiences.

Exploring the longitudinal relationships between the use of grammar in text messaging and performance on grammatical tasks.

Research has demonstrated that use of texting slang (textisms) when text messaging does not appear to impact negatively on children's literacy outcomes and may even benefit children's spelling attainment. However, less attention has been paid to the impact of text messaging on the development of children's and young people's understanding of grammar. This study therefore examined the interrelationships between children's and young adults' tendency to make grammatical violations when texting and their performance on formal assessments of spoken and written grammatical understanding, orthographic processing and spelling ability over the course of 1 year. Zero-order correlations showed patterns consistent with previous research on textism use and spelling, and there was no evidence of any negative associations between the development of the children's performance on the grammar tasks and their use of grammatical violations when texting. Adults' tendency to use ungrammatical word forms ('does you') was positively related to performance on the test of written grammar. Grammatical violations were found to be positively associated with growth in spelling for secondary school children. However, not all forms of violation were observed to be consistently used in samples of text messages taken 12 months apart or were characteristic of typical text messages. The need to differentiate between genuine errors and deliberate violation of rules is discussed, as are the educational implications of these findings.

Sensitivity to the acoustic correlates of lexical stress and their relationship to reading in skilled readers.

The role of suprasegmental information in reading processes is a growing area of interest, and sensitivity to lexical stress has been shown to explain unique variance in reading development. However, less is known about its role in skilled reading. This study aimed to investigate the acoustic features of suprasegmental information using a same/different cross-modal matching task. Sixty-four adult participants completed standardized measures of reading accuracy, reading speed, and comprehension and performed an experimental task. The experimental task required the participants to identify whether non-speech acoustic sequences matched the characteristics of written words. The findings indicated differences in responses depending on where the lexical stress was required for the word. Moreover, evidence was found to support the view that amplitude information is part of the word knowledge retrieval process in skilled reading. The findings are discussed relative to models of reading and the role of lexical stress in lexical access.

A longitudinal study of children's text messaging and literacy development.

Recent studies have shown evidence of positive concurrent relationships between children's use of text message abbreviations ('textisms') and performance on standardized assessments of reading and spelling. This study aimed to determine the direction of this association. One hundred and nineteen children aged between 8 and 12 years were assessed on measures of general ability, reading, spelling, rapid phonological retrieval, and phonological awareness at the beginning and end of an academic year. The children were also asked to provide a sample of the text messages that they sent over a 2-day period. These messages were analyzed to determine the extent to which textisms were used. It was found that textism use at the beginning of the academic year was able to predict unique variance in spelling performance at the end of the academic year after controlling for age, verbal IQ, phonological awareness, and spelling ability at the beginning of the year. When the analysis was reversed, reading and spelling ability were unable to predict unique variance in textism usage. These data suggest that there is some evidence of a causal contribution of textism usage to spelling performance in children aged 8-12 years. However, when the measure of rapid phonological retrieval (rapid picture naming) was controlled in the analysis, the relationship between textism use and spelling ability just failed to reach statistical significance, suggesting that phonological access skills may mediate some of the relationship between textism use and spelling performance.

Use of text message abbreviations and literacy skills in children with dyslexia.

This small-scale study compared 10 to 13-year-old dyslexic children's use of text message abbreviations with that of reading age- and chronological age-matched controls. There were no significant differences in the proportion of textisms used between the dyslexic children and the two control groups, although a preference for non-phonetic text abbreviations was observed in the dyslexic group. Unlike the controls, there was little evidence of an association between phonological awareness and textism use in children with dyslexia. These results are discussed in relation to strategy use by dyslexic children when decoding text.

Children's patterns of reasoning about reading and addition concepts.

Children's reasoning was examined within two educational contexts (word reading and addition) so as to understand the factors that contribute to relational reasoning in the two domains. Sixty-seven 5- to 7-year-olds were given a series of related words to read or single-digit addition items to solve (interspersed with unrelated items). The frequency, accuracy, and response times of children's self-reports on the conceptually related items provided a measure of relational reasoning, while performance on the unrelated addition and reading items provided a measure of procedural skill. The results indicated that the children's ability to use conceptual relations to solve both reading and addition problems enhanced speed and accuracy levels, increased with age, and was related to procedural skill. However, regression analyses revealed that domain-specific competencies can best explain the use of conceptual relations in both reading and addition. Moreover, a cluster analysis revealed that children differ according to the academic domain in which they first apply conceptual relations and these differences are related to individual variation in their procedural skills within these particular domains. These results highlight the developmental significance of relational reasoning in the context of reading and addition and underscore the importance of concept-procedure links in explaining children's literacy and arithmetical development.

Exploring the relationship between children's knowledge of text message abbreviations and school literacy outcomes.

This paper presents a study of 88 British 10-12-year-old children's knowledge of text message (SMS) abbreviations ('textisms') and how it relates to their school literacy attainment. As a measure of textism knowledge, the children were asked to compose text messages they might write if they were in each of a set of scenarios. Their text messages were coded for types of text abbreviations (textisms) used, and the ratio of textisms to total words was calculated to indicate density of textism use. The children also completed a short questionnaire about their mobile phone use. The ratio of textisms to total words used was positively associated with word reading, vocabulary, and phonological awareness measures. Moreover, the children's textism use predicted word reading ability after controlling for individual differences in age, short-term memory, vocabulary, phonological awareness and how long they had owned a mobile phone. The nature of the contribution that textism knowledge makes to children's word reading attainment is discussed in terms of the notion of increased exposure to print, and Crystal's (2006a) notion of ludic language use.

Hassler and Dieckmann's seminal paper on stereotactic thalamotomy for Gilles de la Tourette syndrome: translation and critical reappraisal.

Papers concerning the use of deep brain stimulation to the thalamus for relief of symptoms of Tourette syndrome have frequently cited a paper by Hassler and Dieckmann, published in 1970. We present a translation of this paper and discussion in English.

Successful treatment of rotary pump thrombus with the glycoprotein IIb/IIIa inhibitor tirofiban.

Despite advances in blood pump technology, thrombus formation within left ventricular assist devices (LVADs) is a life-threatening complication with few therapeutic options. A 38-year-old woman who underwent rotary LVAD implantation as a bridge to cardiac transplant developed labile flows (4 to >10 liters), associated with power spikes (4 to 12 watts) and an increase in plasma free hemoglobin (0.86 g/liter), consistent with pump thrombus at Day 140 post-LVAD implantation, despite thromboprophylaxis with aspirin and warfarin. Within 12 hours of commencing an intravenous infusion of tirofiban at a rate of 0.1 mug/kg/min, there were signs of improvement of pump dysfunction, and complete resolution was evident at Day 4 with, stable flows, power consumption and normalization of plasma free hemoglobin. Tirofiban may be considered as an alternative thrombolytic treatment strategy in rotary pump thrombus to avoid the need for LVAD replacement.

First successful bridge to myocardial recovery with a HeartWare HVAD.

In this report we describe the first successful bridge to myocardial recovery with the HeartWare HVAD. Assessment for explantation included serial echocardiography, hemodynamic monitoring, metabolic analysis and manipulation of pump speed, both at rest and during exercise. A protocol for assessing the degree of myocardial recovery without stopping the device is described.

Sensitivity to visual and auditory stimuli in children with developmental dyslexia.

This study considered the extent to which 23 children with dyslexia differed from 23 reading age (RA) and 23 chronological age (CA) matched controls in their ability to make temporal judgements about auditory and visual sequences of stimuli, and in the speed of their reactions to the onsets and offsets of visual and auditory stimuli. The children with dyslexia were slower (p = 0.039) than the CA controls in their reactions to non-verbal auditory onsets (tones), were less able to recognize the first stimulus of a sequence of tones (p = 0.022), and were less accurate in identifying the initial phoneme of a sequence of three (p < 0.001). These characteristics may be manifestations of an impaired temporal processing system for rapid auditory stimuli. CA controls responded more quickly to tone onsets than to tone offsets (p = 0.025), but the dyslexic and RA groups showed no significant difference (p > 0.05) in their reaction times to onsets and offsets of these non-verbal auditory stimuli. Dyslexic readers showed impairment compared with CA controls in responding to the last of a sequence of three non-verbal visual stimuli (shapes), p = 0.02. Reaction times in the visual and auditory onset and offset tasks were richly intercorrelated in the control groups, but the dyslexic group did not show as many significant correlations in reaction times between the auditory and visual domains, or between the onset and offset RTs within each modality. These results suggest that there may be a less integrated cross-modal and intra-modal temporal system in children with dyslexia than in controls. In many of the measures in this study, the performance of the dyslexic group resembled that of the RA control group but differed from CA controls, which implies a developmental delay. The possibility that such a cognitive delay may be related to an underlying neurological disorder is discussed.

Effect of carbohydrate intake on half-marathon performance of well-trained runners.

Eighteen highly-trained runners ran two half marathons in mild environmental conditions, 3 wk apart, consuming either 426 +/- 227 mL of a flavored placebo drink (PLACEBO) or an equivalent volume of water (386 +/- 185 mL) and a commercial gel (GEL) supplying 1.1 +/- 0.2 g/kg body mass (BM) carbohydrate (CHO). Voluntary consumption of this fluid was associated with a mean BM change of approximately 2.4%. Runners performed better in their second race by 0.9% or 40 s (P = 0.03). Three runners complained of gastrointestinal discomfort in GEL trial, which produced a clear impairment of half-marathon performance by 2.4% or 105 s (P=0.03). The effect of GEL on performance was trivial: time was improvedby 0.3% or 14 s compared with PLACEBO (P = 0.52). Consuming the gel was associated with a 2.4% slower time through the 2 x 200 m feed zone; adding a trivial approximately 2 s to race time. Although benefits to half marathon performance were not detected, the theoretical improvement during 1-h exercise with CHO intake merits further investigation.