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Catheter Cardiovasc Interv ; 80(4): 539-45, 2012 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-22311896

RESUMO

OBJECTIVES: To investigate rates of and reasons for second and subsequent stent procedures in an unselected, "real-world" population. BACKGROUND: Repeat stenting is the primary difference reported in clinical trials of alternative revascularization strategies. The incidence, indication, and outcome for repeat stenting in contemporary practice outside the more selective populations of trials and registries has not been described. METHOD: All patients undergoing a first percutaneous coronary intervention (PCI) procedure with stenting from January 2001 to August 2009 (10,509) from a large UK tertiary referral and district general hospital were identified. Mortality and the incidence, timing, and indication for repeat revascularization in this population were investigated from patient records. RESULTS: Of 10,509 patients undergoing a first PCI and stent implant 23.5% underwent repeat angiography of which 11.2% required repeat PCI and 2% coronary artery bypass grafting (median follow-up of 3.8 years). A total of 1.3% went on to a third PCI. The commonest indication for repeat stenting was disease progression remote from the original stent (46%) and planned staged PCI (23%); 21% had a stent-related indication. Functional assessment before repeat stenting was used in one-third of stable patients. Mortality was 2.5% per annum. CONCLUSIONS: In contemporary practice, patients undergoing a first stenting procedure have a low subsequent mortality, and the substantial majority (86.4%) requires no further revascularization over a median 3.8 year follow-up. For those who do require repeat stenting, this is most commonly at a site remote from the first stent.


Assuntos
Ponte de Artéria Coronária , Doença da Artéria Coronariana/terapia , Reestenose Coronária/terapia , Trombose Coronária/terapia , Intervenção Coronária Percutânea , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença da Artéria Coronariana/mortalidade , Doença da Artéria Coronariana/cirurgia , Reestenose Coronária/etiologia , Reestenose Coronária/mortalidade , Reestenose Coronária/cirurgia , Trombose Coronária/etiologia , Trombose Coronária/mortalidade , Trombose Coronária/cirurgia , Progressão da Doença , Inglaterra , Feminino , Hospitais de Distrito , Hospitais Gerais , Humanos , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Intervenção Coronária Percutânea/efeitos adversos , Intervenção Coronária Percutânea/instrumentação , Intervenção Coronária Percutânea/mortalidade , Modelos de Riscos Proporcionais , Retratamento , Stents , Centros de Atenção Terciária , Fatores de Tempo , Resultado do Tratamento
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