RESUMO
It presents information on incidence and mortality from cancer in the European Union, allows access to cancer database (EUCAN), and allows downloads of recommendations for cancer registries.
Assuntos
Neoplasias/epidemiologia , Neoplasias/mortalidade , Organização Mundial da SaúdeRESUMO
It provides links on TP53 mutation: Meetings and events, definitions and function, clinical information, sequencing methods, Other TP53 mutation databases and resources, related proteins and information on cancer and tumor genes.
Assuntos
Genes p53 , Mutação , Mutação em Linhagem GerminativaRESUMO
Downloadable database which provides a description of the mutation, an identification of the biological sample in which it was found, informations on the individual from whom the sample has been isolated and references the publication in which the mutation was originally described. Microsoft Access or File Maker Pro are needed.
Assuntos
Genes p53 , MutaçãoRESUMO
It presents lists of polymorphisms which do alter and do not alter the amino acid sequence of P53, and polymorphisms in non coding regions of the P53 gene.
Assuntos
Polimorfismo Genético , Genes p53 , MutaçãoRESUMO
It examines the scientific basis for possible species differences in mechanisms by which thyroid follicular-cell tumours in mice and rats, renal tubule-cell tumours in male rats and urinary bladder tumours in rats may be produced.
Assuntos
Neoplasias Renais/etiologia , Neoplasias Urológicas/etiologia , Ratos , Animais de Laboratório , Toxicologia , OncologiaRESUMO
It evaluates the use of short- and medium-term assays with end-points of neoplasia or lesions that are precursors to neoplasia, and attempts to define the role of data from genetic toxicology in the prediction of carcinogenic hazard.
Assuntos
Testes de Carcinogenicidade , Carcinógenos/toxicidade , ToxicologiaRESUMO
It addresses the strengths, weaknesses and gaps in the present knowledge on genotoxicity, fibre characterization, cell proliferation and activation, and animal studies, and provides answers to specific questions on the relevance of mechanistic data from in-vitro and in-vivo assays in the assessment of the carcinogenic risk of fibres to humans.
Assuntos
Mutagênicos , Carcinógenos , Testes de Mutagenicidade , Testes de Carcinogenicidade , ToxicologiaRESUMO
It discusses the characteristics of peroxisome proliferation, hepatocarcinogenicity in experimental animals, peroxisome proliferation as a biological marker for hepatocarcinogenesis, and peroxisome proliferators, human response and hazard.
Assuntos
Proliferadores de Peroxissomos/efeitos adversos , Peroxissomos , CarcinógenosRESUMO
It presents 104 abstracts of projects (randomised intervention trials covering areas of primary prevention, chemoprevention and secondary prevention) carried out in 31 countries.
Assuntos
Neoplasias/prevenção & controle , Pesquisa , Oncologia , ProjetosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of polychlorinated dibenzo-para-dioxins and dibenzofurans.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Dioxinas/efeitos adversosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of some viruses.
Assuntos
Testes de Carcinogenicidade , Herpesvirus Humano 4/patogenicidade , Herpesvirus Humano 8/patogenicidade , Neoplasias/virologiaRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of some organic chemicals, hydrazine and hydrogen peroxide.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Compostos Orgânicos/efeitos adversos , Hidrazinas/efeitos adversos , Peróxido de Hidrogênio/efeitos adversosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and experimental animals of oral contraceptives, progestogens, and oestrogen.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Estrogênios/efeitos adversos , Terapia de Reposição de Estrogênios/efeitos adversosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and experimental animals of some chemical compounds.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Isotiocianatos/efeitos adversos , Atrazina/efeitos adversos , Clorofórmio/efeitos adversos , Ciclamatos/efeitos adversos , Ácido Nitrilotriacético/efeitos adversos , Acetaminofen/efeitos adversos , Quercetina/efeitos adversos , Sacarina/efeitos adversosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and experimental animals of surgical implants and other foreign bodies.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Próteses e Implantes/efeitos adversos , Corpos EstranhosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of ionizing radiation.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Radiação IonizanteRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of some antiviral and antineoplastic drugs.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Antivirais/efeitos adversos , Hidroxiureia/efeitos adversos , Fenolftaleína/efeitos adversos , Vitamina K/efeitos adversosRESUMO
It presents data reported and results of carcinogenicity evaluation for humans and animals of some industrial chemicals.
Assuntos
Testes de Carcinogenicidade , Toxicologia , Carcinógenos , Dietilexilftalato/efeitos adversos , Cumarínicos/efeitos adversos , Toluidinas/efeitos adversos , Piridinas/efeitos adversosRESUMO
It presents updating of the IARC carcinogenicity evaluations for several chemical compounds (from Acetamide to Vinyl chloride).