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Genet Epidemiol ; 6(5): 619-24, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2591731

RESUMO

A complex segregation analysis of acid phosphatase activity in 50 British families showed that the essential features of the acid phosphatase polymorphism, i.e., a major gene with three alleles, is retrieved by using the biallelic mixed model. The estimates of gene frequency and displacement obtained from segregation analysis were in agreement with those obtained from electrophoretic studies. In addition, there was evidence for a multifactorial component.


Assuntos
Fosfatase Ácida/genética , Alelos , Mapeamento Cromossômico , Genética Populacional , Inglaterra , Eritrócitos/enzimologia , Humanos , Modelos Genéticos , Fenótipo , Polimorfismo Genético
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