Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Aging Dis ; 13(4): 1005-1014, 2022 Jul 11.
Artigo em Inglês | MEDLINE | ID: mdl-35855337

RESUMO

Acarbose can extend the life span of mice through a process involving the gut microbiota. Several factors affect the life span, including mitochondrial function, cellular senescence, telomere length, immune function, and expression of longevity-related genes. In this review, the effects of acarbose-regulated gut microbiota on the life span-influencing factors have been discussed. In addition, a novel theoretical basis for improving our understanding of the mechanisms by which acarbose extends the life span of mice has been suggested.

2.
Hunan Yi Ke Da Xue Xue Bao ; 27(2): 143-5, 2002 Apr 28.
Artigo em Chinês | MEDLINE | ID: mdl-12575343

RESUMO

OBJECTIVE: To analyse the clinical characteristics of fatty livers of patients with the insulin resistance syndrome. METHODS: With echographic histogram, the acoustic intensity (AV) in six different areas of each fatty liver was measured in 61 patients with the insulin resistance syndrome. The relationship between the average value of AV and some clinical or biochemical parameters were analysed. RESULTS: There were significant differences in AV between the area near the portal venous and the area near the gall bladder, and between males and females as well. AV was positively related to the body mass ratio (BMI), waist circle (W) and hip circle (H); AV was positively related to the waist-hip ratio (WHR) or insulin sensitive index (ISI) in trend; and AV was negatively related to high density lipoprotein cholesterin (HDL-C). CONCLUSION: In patients with the insulin resistance syndrome, fatty density of livers is higher near the portal venous than near the gall bladder. The fatty liver is more serious in females than in males. BMI, W, H and serum HDL-C levels are useful parameters in evaluating the severity of fatty livers.


Assuntos
Fígado Gorduroso/diagnóstico por imagem , Síndrome Metabólica/diagnóstico por imagem , Adulto , Índice de Massa Corporal , HDL-Colesterol/sangue , Fígado Gorduroso/etiologia , Feminino , Humanos , Fígado/diagnóstico por imagem , Masculino , Síndrome Metabólica/complicações , Pessoa de Meia-Idade , Ultrassonografia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...