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1.
Sci Rep ; 10(1): 1872, 2020 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-32024892

RESUMO

A polarisation-division-multiplexing (PDM)-based four-level pulse amplitude modulation (PAM4) fibre-free-space optical (FSO) convergent system with optical band-pass filters (OBPFs) for polarisation de-multiplexing is feasibly demonstrated for the first time. In a PDM scenario with PAM4 modulation, the transmission capacity of fibre-FSO convergent systems is enhanced four times with an aggregate channel capacity of 128 Gb/s (64 Gb/s PAM4/polarisation × 2 polarisations). With an OBPF, polarisation-tracking free de-multiplexing is attained by eliminating other optical carrier with orthogonal polarisation. An OBPF is a simple polarisation de-multiplexing scheme in which the polarisation-orthogonal carrier can be effectively de-multiplexed and the cross-polarisation interference can be nearly eliminated. Compared with traditional PDM-based fibre-FSO convergent systems with sophisticated polarisation-tracking mechanism and elaborate digital signal processing (DSP) approach, it reveals a noteworthy one with the advantage of simplicity. Through 25 km single-mode fibre transport and 500 m FSO link, sufficiently low bit error rate and qualified PAM4 eye diagrams are attained. This proposed polarisation-tracking free PDM-based fibre-FSO convergent system is notable because it not only incorporates the fibre backbone and optical wireless feeder, but it also simplifies the framework since complicated polarisation-tracking mechanism and DSP approach are not involved.

2.
Sci Rep ; 9(1): 8605, 2019 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-31197214

RESUMO

We have, so far as we know, proposed and demonstrated the first 30 Gb/s four-level pulse amplitude modulation (PAM4) underwater wireless laser transmission (UWLT) system with an optical beam reducer/expander over 12.5-m piped underwater channel/2.5-m high-turbidity harbour underwater channel. In piped underwater links, the performances of PAM4 UWLT systems get better with beam reduction given a small amount of light absorbed by the piped water. In highly turbid harbour underwater links, the performances of PAM4 UWLT systems get better with beam expansion given a large amount of scattered light received by the optical receiver. The effect of high-turbidity harbour water that induces scattering angle (beam divergence) on beam diameter is analyzed and optimised to enhance the transmission performances. This proposed PAM4 UWLT system, which uses an optical beam reducer/expander, provides a practical choice for high transmission capacity and considerably develops clarity and high-turbidity scenarios. It presents promising features for affording a high-transmission-rate underwater optical wireless transmission and opening an access to accelerate wide applications of UWLT systems.

3.
Opt Express ; 25(9): 9743-9754, 2017 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-28468354

RESUMO

A bidirectional fiber-invisible laser light communication (IVLLC) and fiber-wireless convergence system with two orthogonally polarized optical sidebands for hybrid cable television (CATV)/millimeter-wave (MMW)/baseband (BB) signal transmission is proposed and experimentally demonstrated. Two optical sidebands generated by a 60-GHz MMW signal are orthogonally polarized and separated into different polarizations. These orthogonally polarized optical sidebands are delivered over a 40-km single-mode fiber (SMF) transport to effectually reduce the fiber dispersion induced by a 40-km SMF transmission and the distortion caused by the parallel polarized optical sidebands. To the best of our knowledge, this work is the first to adopt two orthogonally polarized optical sidebands in a bidirectional fiber-IVLLC and fiber-wireless convergence system to reduce fiber dispersion and distortion effectually. Good carrier-to-noise ratio, composite second order, composite triple beat, and bit error rate (BER) are achieved for downlink transmission at a 40-km SMF operation and a 100-m free-space optical (FSO) link/3-m RF wireless transmission. For up-link transmission, good BER performance is acquired over a 40-km SMF transport and a 100-m FSO link. The approach presented in this work signifies the advancements in the convergence of SMF-based backbone and optical/RF wireless-based feeder.

4.
Opt Express ; 20(9): 9919-24, 2012 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-22535084

RESUMO

A wavelength-division-multiplexing (WDM) visible light communiction (VLC) system employing red and green laser pointer lasers (LPLs) with directly modulating data signals is proposed and experimentally demonstrated. With the assistance of preamplifier and adaptive filter at the receiving sites, low bit error rate (BER) at 10 m/500 Mbps operation is obtained for each wavelength. The use of preamplifier and adaptive filter offer significant improvements for free-space transmission performance. Improved performance of BER of <10(-9), as well as better and clear eye diagram were achieved in our proposed WDM VLC systems. LPL features create a new category of good performance with high-speed data rate, long transmission length (>5m), as well as easy handling and installation. This proposed WDM VLC system reveals a prominent one to present its advancement in simplicity and convenience to be installed.


Assuntos
Amplificadores Eletrônicos , Lasers , Telecomunicações/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Micro-Ondas
5.
Am J Physiol Cell Physiol ; 296(5): C1133-9, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19279235

RESUMO

This article reports on a study of the effect of trichostatin A (TSA), an inhibitor of histone deacetylase, on lipopolysaccharide (LPS)-induced expression of inducible nitric oxide synthase (iNOS) in RAW 264.7 macrophages and its underlying mechanisms. TSA pretreatment potently diminishes LPS-stimulated nitric oxide (NO) release and both mRNA and protein levels of iNOS in macrophages. The effects of TSA and LPS on transcription factors binding to two LPS-responsive elements within the iNOS promoter, one binding the NF-kappaB site and the other the octamer element, were investigated. Results show that TSA did not alter the LPS-activated NF-kappaB activity demonstrated by the nuclear translocation of p50 and p65 and by a NF-kappaB-driven reporter gene expression system. In addition, neither TSA nor LPS changed the expression of Oct-1, a ubiquitously expressed octamer binding protein. However, TSA suppressed the LPS-induced expression of Oct-2, another octamer binding protein, at both mRNA and protein levels. Chromatin immunoprecipitation assays revealed that binding of Oct-2 to the iNOS promoter was enhanced by LPS treatment; however, pretreatment with TSA resulted in loss of this binding. Moreover, forced expression of Oct-2 by transfection of pCG-Oct-2 plasmid restored the TSA-suppressed iNOS expression elevated by LPS stimulation, further indicating that Oct-2 activation is a crucial step for transcriptional activation of the iNOS gene in response to LPS stimulation in macrophages. This study demonstrates that TSA diminishes iNOS expression in LPS-treated macrophages by inhibiting Oct-2 expression and thus reducing the production of NO.


Assuntos
Inibidores Enzimáticos/farmacologia , Ácidos Hidroxâmicos/farmacologia , Lipopolissacarídeos/farmacologia , Macrófagos/fisiologia , Óxido Nítrico Sintase Tipo II/genética , Fator 2 de Transcrição de Octâmero/metabolismo , Animais , Western Blotting , Linhagem Celular , Expressão Gênica/efeitos dos fármacos , Expressão Gênica/imunologia , Macrófagos/citologia , Macrófagos/efeitos dos fármacos , Camundongos , Óxido Nítrico/metabolismo , Óxido Nítrico Sintase Tipo II/metabolismo , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Transfecção
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